Patents by Inventor Seiichi Araki

Seiichi Araki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7579325
    Abstract: The present invention provides medicines for preventing or treating infectious diseases, sepsis and/or septic shock, which exhibit excellent immunostimulating effects. More specifically, the invention provides medicines for immunostimulation and infection-protection and -treatment, and/or for preventing or treating sepsis and septic shock, which comprise reduced riboflavin and/or reduced riboflavin derivative or pharmacologically acceptable salt thereof. Also provided are methods for using them in the prevention and/or treatment of infectious disorders such as sepsis and septic shock.
    Type: Grant
    Filed: March 19, 2002
    Date of Patent: August 25, 2009
    Assignee: Eisai R & D Management Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Yoshiki Sugihara, Toshio Toyosawa
  • Patent number: 7416745
    Abstract: A preventive or remedy for infection, an anti-endotoxin agents, a vaccine adjuvants and a growth promoter each comprising a sugar cane-derived extract as an active ingredient which agent is safe to man and animals. Also presented are foods and feeds comprising these agents.
    Type: Grant
    Filed: November 1, 2006
    Date of Patent: August 26, 2008
    Assignee: Mitsui Sugar Co. Ltd
    Inventors: Takeo Mizutani, Kenji Koge, Yukie Nagai, Hiroshi Murakami, Toshikazu Kawai, Jun Kashimura, Takeo Shimizu, Seiichi Araki, Mamoru Suzuki
  • Patent number: 7368136
    Abstract: A preventive or remedy for infection, an anti-endotoxin agents, a vaccine adjuvants and a growth promoter each comprising a sugar cane-derived extract as an active ingredient which agent is safe to man and animals. Also presented are foods and feeds comprising these agents.
    Type: Grant
    Filed: November 1, 2006
    Date of Patent: May 6, 2008
    Assignee: Mitsui Sugar Co., Ltd.
    Inventors: Takeo Mizutani, Kenji Koge, Yukie Nagai, Hiroshi Murakami, Toshikazu Kawai, Jun Kashimura, Takeo Shimizu, Seiichi Araki, Mamoru Suzuki
  • Publication number: 20070128206
    Abstract: A preventive or remedy for infection, an anti-endotoxin agents, a vaccine adjuvants and a growth promoter each comprising a sugar cane-derived extract as an active ingredient which agent is safe to man and animals. Also presented are foods and feeds comprising these agents.
    Type: Application
    Filed: November 1, 2006
    Publication date: June 7, 2007
    Applicant: MITSUI SUGAR CO., LTD.
    Inventors: SEIICHI ARAKI, MAMORU SUZUKI, TAKEO MIZUTANI, KENJI KOGE, YUKIE NAGAI, HIROSHI MURAKAMI, TOSHIKAZU KAWAI, JUN KASHIMURA, TAKEO SHIMIZU
  • Publication number: 20070059389
    Abstract: A preventive or remedy for infection, an anti-endotoxin agents, a vaccine adjuvants and a growth promoter each comprising a sugar cane-derived extract as an active ingredient which agent is safe to man and animals. Also presented are foods and feeds comprising these agents.
    Type: Application
    Filed: November 1, 2006
    Publication date: March 15, 2007
    Applicant: MITSUI SUGAR CO., LTD.
    Inventors: SEIICHI ARAKI, MAMORU SUZUKI, TAKEO MIZUTANI, KENJI KOGE, YUKIE NAGAI, HIROSHI MURAKAMI, TOSHIKAZU KAWAI, JUN KASHIMURA, TAKEO SHIMIZU
  • Patent number: 7150885
    Abstract: A preventive or remedy for infection, an anti-endotoxin agents, a vaccine adjuvants and a growth promoter each comprising a sugar cane-derived extract as an active ingredient which agent is safe to man and animals. Also presented are foods and feeds comprising these agents.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: December 19, 2006
    Assignee: Mitsui Sugar Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Takeo Mizutani, Kenji Koge, Yukie Nagai, Hiroshi Murakami, Toshikazu Kawai, Jun Kashimura, Takeo Shimizu
  • Publication number: 20050208124
    Abstract: A medicament is provided containing as an active ingredient at least one of riboflavin, a riboflavin derivative or a pharmacologically acceptable salt thereof, which has the action of suppressing IL-1?, IL-6, IL-10, INF-?, TNF-?, GM-CSF, IL-8, MCP-1 and other cytokines. Moreover, a preventative or therapeutic agent for inflammatory diseases accompanied by hypercytokinemia is provided which has excellent cytokine suppression effect.
    Type: Application
    Filed: March 11, 2003
    Publication date: September 22, 2005
    Applicant: EISAI Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Kohtarou Kodama, Toshio Toyosawa
  • Publication number: 20040106562
    Abstract: Preventives and remedies with an excellent immunopotentiating effect for infections, sepsis and/or septic shock. More specifically, immunopotentiators/preventitives and remedies for infections and remedies for sepsis and septic shock comprising as the active ingredient reduced riboflavin and/or reduced riboflavin derivatives or pharmacologically acceptable salts thereof.
    Type: Application
    Filed: September 19, 2003
    Publication date: June 3, 2004
    Inventors: Seiichi Araki, Mamoru Suzuki, Yoshiki Sugihara, Toshio Toyosawa
  • Publication number: 20030147978
    Abstract: A preventive or remedy for infection, an anti-endotoxin agents, a vaccine adjuvants and a growth promoter each comprising a sugar cane-derived extract as an active ingredient which agent is safe to man and animals. Also presented are foods and feeds comprising these agents.
    Type: Application
    Filed: June 20, 2001
    Publication date: August 7, 2003
    Inventors: Seiichi Araki, Mamoru Suzuki, Takeo Mizutani, Kenji Koge, Yukie Nagai, Hiroshi Murakami, Toshikazu Kawai, Jun Kashimura, Takeo Shimizu
  • Publication number: 20030143265
    Abstract: It has unexpectedly been found that the administration of high doses of riboflavin or derivatives thereof (including, but not limited to salts and prodrugs), results in an effective treatment for sepsis. Thus, the present invention provides methods for treating sepsis by administering to a subject in need thereof a high dose of a composition comprising riboflavin or derivatives thereof.
    Type: Application
    Filed: December 19, 2001
    Publication date: July 31, 2003
    Inventors: Seiichi Araki, Akira Kato, Katsumi Onai
  • Patent number: 6288128
    Abstract: A &bgr;,&ggr;-dihydropolyprenyl alcohol derivative having the formula: wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group, is new and useful as a prophylactic therapeutic agent for human and animal immuno-deficiency deseases and phylactic agent against human and animal infectious deseases. Another disclosed polyprenyl compound is also useful as the same agent.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: September 11, 2001
    Assignee: Eisai Co., Ltd.
    Inventors: Masaichi Yamamoto, Seiichi Araki, Hiroshi Yamamoto, Isao Yamatsu, Takeshi Suzuki, Akiharu Kajiwara, Yoshikazu Suzuki, Haruyoshi Arai
  • Patent number: 6111131
    Abstract: A .beta.,.gamma.-dihydropolyprenyl alcohol derivative having the formula: ##STR1## wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group, is new and useful as a prophylactic therapeutic agent for human and animal immuno-deficiency deseases and phylactic agent against human and animal infectious deseases. Another disclosed polyprenyl compound is also useful as the same agent.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: August 29, 2000
    Assignee: Eisai Co., Ltd.
    Inventors: Masaichi Yamamoto, Seiichi Araki, Hiroshi Yamamoto, Isao Yamatsu, Takeshi Suzuki, Akiharu Kajiwara, Yoshikazu Suzuki, Haruyoshi Arai
  • Patent number: 5945420
    Abstract: An immunopotentiating and infection protective agent comprising riboflavin and/or a riboflavin derivative, which is safe for the human, animals or the like, an immunopotentiating and infection protective agent comprising riboflavin and/or a riboflavin derivative and (1) proline and/or glutamine, (2) an antibiotic, or (3) a water-soluble polymer or lecithin, which is safe for the human, animals or the like, and a process for the production thereof.
    Type: Grant
    Filed: April 15, 1998
    Date of Patent: August 31, 1999
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto
  • Patent number: 5814632
    Abstract: An immunopotentiating and infection protective agent comprising riboflavin and/or a riboflavin derivative, which is safe for the human, animals or the like, an immunopotentiating and infection protective agent comprising riboflavin and/or a riboflavin derivative and (1) proline and/or glutamine, (2) an antibiotic, or (3) a water-soluble polymer or lecithin, which is safe for the human, animals or the like, and a process for the production thereof.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: September 29, 1998
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto
  • Patent number: 5741494
    Abstract: Synergistic compositions of egg white and Bacillus subtilis, Bacillus celleus, Lactobacillus lactis, Lactobacillus casei, Bifidobacterium bifidum or Clostridium and optionally also containing garlic for treating and preventing infections and other uses are described.
    Type: Grant
    Filed: October 31, 1995
    Date of Patent: April 21, 1998
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto
  • Patent number: 5658958
    Abstract: Various .beta.,.gamma.-dihydropolyprenyl alcohol derivatives having the formula: ##STR1## wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group are effective at pritigating stress in animals.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: August 19, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Masaichi Yamamoto, Seiichi Araki, Hiroshi Yamamoto, Isao Yamatsu, Takeshi Suzuki, Akiharu Kajiwara, Yoshikazu Suzuki, Haruyoshi Arai
  • Patent number: 5628998
    Abstract: A method for improving amoxicillin absorption in mammals such as pigs by administering the amoxicillin to the mammal in combination with one or more of the following plant substances: Rosa roxburghii, Artemisiae argyi folium and Brassica oleracea var. capitata L. The plant substance is administered in its natural state, dried, or as an extract.
    Type: Grant
    Filed: May 10, 1995
    Date of Patent: May 13, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto, Tadashi Ueki
  • Patent number: 5624671
    Abstract: A pharmaceutical composition or feed, which is useful for immunopotentiating and protecting an animal from infectious diseases, regulating a function of the digestive tract, improving antibiotic absorption, accelerating growth of an animal or improving egg production rate, egg weight, egg quality or eggshell strength of an animal, comprising a pharmaceutically effective amount of a substance selected from the group consisting of Rosa roxburghii, Artemisiae argyi folium and Brassica oleracea var. capitata L. and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: May 10, 1995
    Date of Patent: April 29, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto, Tadashi Ueki
  • Patent number: 5556625
    Abstract: A method of reducing the symptoms of diarrhea by administering to an animal a composition containing Rosa roxburghii, Artemisiae argyi folium, and Brassica oleracea var. capitata L.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: September 17, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto, Tadashi Ueki
  • Patent number: 5556624
    Abstract: A method for immunopotentiating and protecting an animal from an infection caused by E. coli is described. The method comprises administering a composition containing Rosa roxburghii, Artemisiae argyi folium, and Brassica oleracea var. capitata L. to the animal.
    Type: Grant
    Filed: November 1, 1994
    Date of Patent: September 17, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto, Tadashi Ueki