Patents by Inventor Serge P. Lichtsteiner

Serge P. Lichtsteiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Producing telomerase activators and inhibitors by screening with purified telomerase
    Patent number: 7067283
    Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: June 27, 2006
    Assignee: Geron Corporation
    Inventors: Scott L. Weinrich, Edward M. Atkinson, III, Serge P. Lichtsteiner, Alain P. Vasserot, Ronald A. Pruzan
  • Using purified telomerase to identify telomerase activators and inhibitors
    Patent number: 6787133
    Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: September 7, 2004
    Assignee: Geron Corporation
    Inventors: Scott L. Weinrich, Edward M. Atkinson, III, Serge P. Lichtsteiner, Alain P. Vasserot, Ronald A. Pruzan
  • Telomerase promoter driving expression of therapeutic gene sequences
    Patent number: 6777203
    Abstract: The present invention is related to novel nucleic acids comprising telomerase reverse transcriptase (TERT) cis-acting transcriptional control sequences, including TERT human and mouse promoter sequences. The present invention is further directed to methods of using these cis-acting transcriptional control sequences, for example, to drive heterologous gene sequences; to modulate the level of transcription of TERT or to isolate novel trans-acting regulatory factors which bind to and modulate the activity of a TERT promoter.
    Type: Grant
    Filed: February 4, 1999
    Date of Patent: August 17, 2004
    Assignee: Geron Corporation
    Inventors: Gregg B. Morin, Serge P. Lichtsteiner, Alain P. Vasserot, Robert R. Adams, William H. Andrews
  • Telomerase reverse transcriptase transcriptional regulatory sequences and methods of using
    Publication number: 20040072787
    Abstract: The present invention is related to novel nucleic acids comprising telomerase reverse transcriptase (TERT) cis-acting transcriptional control sequences, including TERT human and mouse promoter sequences. The present invention is further directed to methods of using these cis-acting transcriptional control sequences, for example, to drive heterologous gene sequences; to modulate the level of transcription of TERT or to isolate novel trans-acting regulatory factors which bind to and modulate the activity of a TERT promoter.
    Type: Application
    Filed: September 29, 2003
    Publication date: April 15, 2004
    Applicant: Geron Corporation
    Inventors: Gregg B. Morin, Serge P. Lichtsteiner, Alain P. Vasserot, Robert R. Adams, William H. Andrews
  • Using purified telomerase to identify telomerase activators and inhibitors
    Publication number: 20030186282
    Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
    Type: Application
    Filed: December 24, 2002
    Publication date: October 2, 2003
    Inventors: Scott L. Weinrich, Edward M. Atkinson, Serge P. Lichtsteiner, Alain P. Vasserot, Ronald A. Pruzan
  • Methods for purifying telomerase
    Patent number: 6545133
    Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: April 8, 2003
    Assignee: Geron Corporation
    Inventors: Scott L. Weinrich, Edward M. Atkinson, III, Serge P. Lichtsteiner, Alain P. Vasserot, Ronald A. Pruzan
  • Purified telomerase
    Patent number: 6517834
    Abstract: This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive charges, intermediate-selectivity matrices, methods that separate molecules based on their size, shape, or buoyant density, and by affinity purification.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: February 11, 2003
    Assignee: Geron Corporation
    Inventors: Scott L. Weinrich, Edward M. Atkinson, III, Serge P. Lichtsteiner, Alain P. Vasserot, Ronald A. Pruzan
  • Purified telomerose
    Patent number: 6261556
    Abstract: This invention provides purified human telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of a first matrix that binds molecules bearing negative charges, a matrix that binds molecules bearing positive charges, a second matrix that binds molecules bearing negative charges, an affinity purification step and a matrix that separates molecules according to their size.
    Type: Grant
    Filed: October 18, 1999
    Date of Patent: July 17, 2001
    Assignee: Geron Corporation
    Inventors: Scott L. Weinrich, Edward M. Atkinson, III, Serge P. Lichtsteiner, Alain P. Vasserot, Ronald A. Pruzan, James T. Kealey
  • Purified telomerase
    Patent number: 5968506
    Abstract: This invention provides purified human telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of a first matrix that binds molecules bearing negative charges, a matrix that binds molecules bearing positive charges, a second matrix that binds molecules bearing negative charges, an affinity purification step and a matrix that separates molecules according to their size.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: October 19, 1999
    Assignee: Geron Corporation
    Inventors: Scott L. Weinrich, Edward M. Atkinson, III, Serge P. Lichtsteiner, Alain P. Vasserot, Ronald A. Pruzan, James T. Kealey