Abstract: The present invention relates to water-soluble binuclear cationic nitrosyl iron complexes with natural aliphatic thiolyls of general formula [Fe2(SR)2(NO)4]SO4, wherein R is sulfur-containing aliphatic ligands of natural origin, preferably, cystamine or penicillamine, to a method for the preparation thereof, to use thereof as an anticancer agent, to an apoptosis inducer, to a pharmaceutical composition comprising said complexes in an effective amount, and to a kit useful for the treatment of cancer diseases.

Abstract: The present invention relates to water-soluble binuclear cationic nitrosyl iron complexes with natural aliphatic thiolyls of general formula [Fe2(SR)2(NO)4]SO4, wherein R is sulfur-containing aliphatic ligands of natural origin, preferably, cystamine or penicillamine, to a method for the preparation thereof, to use thereof as an anticancer agent, to an apoptosis inducer, to a pharmaceutical composition comprising said complexes in an effective amount, and to a kit useful for the treatment of cancer diseases.

Abstract: The invention relates to dicarbonic acid derivatives and concerns dicarbonic acid monooxydamines and dioxydamides, which are physiologically active substances and can be used as low-toxic and non-toxic agents for enhancing the anti-tumor and anti-metastasis effects of known cytostatics (cyclophosphane and cisplatin) in cytostatic chemotherapy of tumors. The object of the present invention is to broaden the assortment of agents affecting a live organism in order to enhance anti-tumor and anti-metastasis effects of known cytostatics. This object is resolved by the properties of dicarbonic acid monooxydamines and dioxydamides. The essence of the invention consists in that dicarbonic acid derivatives, the formulas of which are presented in the specification, are proposed as agents for enhancing anti-tumor and anti-metastasis effects of cytostatics.

Abstract: The present invention discloses a class of metallocene catalyst systems suitable for the homogeneous polymerisation of ethylene or alpha olefins that does not require the addition of aluminoxane or perfluorophenylborates as activating agent.

Abstract: The invention relates to a method for the preparation of the polyolefinic bases of synthetic oils by the cationic oligomerization of olefinic feedstock and can be used in the petrochemical industry. A new method for the preparation of the polyolefinic bases of synthetic oils has been developed, which comprises the steps of conditioning olefinic feedstock, preparing and dosing in a reactor, solutions and suspension of the components of a catalytic system Al(O)—HCl-TBCh, isomerizing alpha-olefins and oligomerizing higher olefins and mixtures thereof under the action of the catalytic system Al(O)—HCl-TBCh, separating spent catalyst, dividing an oligomerizate into fractions and hydrogenating the fractions separated under the action of a catalyst Pd(0.2% w)/A1203+NaOH. The invention provides the improvement of all steps of the method elaborated.

Abstract: The invention relates to dicarbonic acid derivatives and concerns dicarbonic acid monooxydamines and dioxydamides, which are physiologically active substances and can be used as low-toxic and non-toxic agents for enhancing the anti-tumor and anti-metastasis effects of known cytostatics (cyclophosphane and cisplatin) in cytostatic chemotherapy of tumors. The object of the present invention is to broaden the assortment of agents affecting a live organism in order to enhance anti-tumor and anti-metastasis effects of known cytostatics. This object is resolved by the properties of dicarbonic acid monooxydamines and dioxydamides. The essence of the invention consists in that dicarbonic acid derivatives, the formulas of which are presented in the specification, are proposed as agents for enhancing anti-tumor and anti-metastasis effects of cytostatics.