Patents by Inventor Sergei Pouhov

Sergei Pouhov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process
    Patent number: 6689911
    Abstract: An integrated process for preparing &agr;-(2,4-disulfophenyl)-N-tert-butylnitrone and its salts is disclosed in which N-tert-butylhydroxylamine acid addition salt is incompletely neutralised so as to leave catalytic amounts of acid and the neutralisation product is condensed with an appropriate aldehyde.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: February 10, 2004
    Assignees: Centaur Pharmaceuticals, Inc., AstraZeneca AB
    Inventors: Henry Kruk, John McGinley, Sergei Pouhov, John Vajda, Allan Wilcox, Jörgen Blixt, Ulf Larsson
  • Novel process for the preparation of alpha-(2-4-disulfophenyl)-n-tert-butylnitrone and pharmaceutically acceptable salts thereof
    Publication number: 20030069442
    Abstract: An integrated process for preparing &agr;-(2,4-disulfophenyl)-N-tert-butylnitrone and its salts is disclosed in which N-tert-butylhydroxylamine acid addition salt is incompletely neutralised so as to leave catalytic amounts of acid and the neutralisation product is condensed with an appropriate aldehyde.
    Type: Application
    Filed: April 5, 2001
    Publication date: April 10, 2003
    Inventors: Henry Kruk, John McGinley, Sergei Pouhov, John Vajda, Allan Wilcox, Jorgen Blixt, Ulf Larsson
  • Process for the preparation of &agr;-(2-4-disulfophenyl)-N-tert-burtylnitrone and pharmaceutically acceptable salts thereof
    Patent number: 6479697
    Abstract: A process for the preparation of &agr;-(2,4-disulfophenyl)-N-tert-butylnitrone diacids and pharmaceutically acceptable salts thereof by the reaction of the corresponding disulfophenyl aldehyde with N-tert-butylhydroxylammonium acetate is disclosed.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: November 12, 2002
    Assignee: AstraZeneca AB
    Inventors: Henry Kruk, John McGinley, Sergei Pouhov, John Vajda, Jörgen Blixt
  • NOVEL PROCESS FOR THE PREPARATION OF ALPHA-(2-4-DISULFOPHENYL)-N-TERT-BURTYLNITRONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
    Publication number: 20020128318
    Abstract: A process for the preparation of &agr;-(2,4-disulfophenyl)-N-tert-butylnitrone diacids and pharmaceutically acceptable salts thereof by the reaction of the corresponding disulfophenyl aldehyde with N-tert-butylhydroxylammonium acetate is disclosed.
    Type: Application
    Filed: April 5, 2001
    Publication date: September 12, 2002
    Inventors: Henry Kruk, John McGinley, Sergei Pouhov, John Vajda, Jorgen Blixt
  • Method for the purification of aryl sulfonic acids and salts
    Publication number: 20020022743
    Abstract: Solid aryl sulfonates are purified by preferentially dissolving impurities into an aqueous liquid phase.
    Type: Application
    Filed: January 5, 2001
    Publication date: February 21, 2002
    Inventors: Sergei Pouhov, Gene Jamieson, John Vajda, Henry Kruk, John McGinley