Patents by Inventor Sergei Vitalievich Grachev

Sergei Vitalievich Grachev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and device for forming an no-containing gas flow for affecting a biological object
    Patent number: 7498000
    Abstract: A method and apparatus for forming NO-containing gas flow to treat a biologic object are disclosed. The NO-containing gas flow is formed from a source gas comprising at least oxygen and nitrogen in a housing (1) comprising at least two electrodes (2,3) insulated from each other, a stationary dc arc discharge being generated and maintained between the electrodes. The NO-containing gas flow is formed from the source gas in the area between the electrodes (2,3) under the effect of the arc discharge and withdrawn through a cooled channel, enabling nitrogen oxide to be fixed in the flow and the temperature of the flow and the NO content therein to be brought to values required to provide efficient therapy of a biologic object.
    Type: Grant
    Filed: February 1, 2002
    Date of Patent: March 3, 2009
    Inventors: Aleksandr Valerievich Pekshev, Andrei Borisovich Vagapov, Sergei Vitalievich Grachev, Nikolai Pavlovich Kozlov, Anatoly Borukhovich Shekhter
  • Method for therapy of liver tumors
    Patent number: 7220425
    Abstract: A method for regional administration of preparations during the therapy of liver tumor, comprising administering a preparation into a branch of the portal vein with the simultaneous occlusion of afferent and efferent lobe vessels (branches of the portal vein proximal the place of puncture, branches of the hepatic artery and lobar hepatic vein) for 5–15 minutes. During catalytic therapy, it is preferable to use Teraphtalum as the preparation and to administer ascorbic acid after termination of occlusion. During photodynamic therapy, it is preferable to use photosens as the preparation and to carry out irradiation of the tumor after 10–35 minutes. This method of administration provides for the predominant accumulation of the preparations in the target lobe (tumor carrier lobe) of the liver, their low penetration into the systemic blood flow, which makes it possible to reduce the dose of the preparation and its general toxicity.
    Type: Grant
    Filed: November 26, 2001
    Date of Patent: May 22, 2007
    Assignees: Federalnoe Gosudarstvennoe Unitarnoe Predpriyatie Gosudarstvenny Nauchny Tsentr “Nauchno-Issledovatelsky Institut Organicheskikh Poluproduktov I Krasitelei” (FGUP GNTTS “Niopik”), Gosudarstevennoe Obrazovatelnoe Uchrezhdenie Vysshego Professionalnogo Obrazovaniya Moskovskaya Meditsinskaya Akademiya IM. I.M. Sechenova RF (Gouvpo MMA IM. I.M. Sechenova MZ RF)
    Inventors: Georgy Nikolaevich Vorozhtsov, Eduard Izrailevich Galperin, Roman Sergeevich Goloschapov, Sergei Vitalievich Grachev, Tatyana Gennadievna Dyuzheva, Natalya Ivanovna Kazachkina, Oleg Leonidovich Kalia, Yury Mikhailovich Luzhkov, Evgeny Antonovich Lukyanets, Vadim Romanovich Nakhamiyaev
  • Method and device for forming an no-containing gas flow for affecting a biological object
    Publication number: 20050218007
    Abstract: A method and apparatus for forming NO-containing gas flow to teat a biologic object are disclosed. The NO-containing gas flow is formed from a source gas comprising at least oxygen and nitrogen in a housing (1) comprising at least two electrodes (2,3) insulated from each other, a stationary dc arc discharge being generated and maintained between the electrodes. The NO-containing gas flow is formed from the source gas in the area between the electrodes (2,3) under the effect of the arc discharge and withdrawn through a cooled channel, this enabling nitrogen oxide to be fixed in the flow and the temperature of the flow and the NO content therein to be brought to values required to provide efficient therapy of a biologic object.
    Type: Application
    Filed: February 1, 2002
    Publication date: October 6, 2005
    Inventors: Aleksandr Pekshev, Andrei Vagapov, Sergei Vitalievich Grachev, Nikolai Kozlov, Anatoly Shekhter
  • Method for regional administration of preparations during therapy of liver tumors
    Publication number: 20030166713
    Abstract: A method for regional administration of preparations during the therapy of liver tumor, comprising administering a preparation into a branch of the portal vein with the simultaneous occlusion of afferent and efferent lobe vessels (branches of the portal vein proximal the place of puncture, branches of the hepatic artery and lobar hepatic vein) for 5-15 minutes.
    Type: Application
    Filed: January 31, 2003
    Publication date: September 4, 2003
    Inventors: Georgy Nikolaevich Vorozhtsov, Eduard Izrailevich Galperin, Roman Sergeevich Goloschapov, Sergei Vitalievich Grachev, Tatyana Gennadievna Dyuzheva, Natalya Ivanova Kazachkina, Oleg Leonidovich Kalia, Yury Mikhailovich Luzhkov, Evgeny Antonovich Lukyantes, Vadim Romanovich Nakhamiyaev