Patents by Inventor Sergio G. Duron

Sergio G. Duron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING AUTISM
    Publication number: 20130096115
    Abstract: Provided herein are PAK inhibitors. Also provided herein are compositions and methods for treating an individual suffering from autism.
    Type: Application
    Filed: December 21, 2010
    Publication date: April 18, 2013
    Applicant: AFRAXIS, INC.
    Inventors: Jay Lichter, David Campbell, Benedikt Vollrath, Sergio G. Durón
  • Controlled release ion channel modulator compositions and methods for the treatment of otic disorders
    Patent number: 8399018
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with ion channel modulators. In these methods, the ion channel modulator compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the ion channel modulator compositions and formulations onto the auris interna target areas, or via perfusion into the auris interna structures.
    Type: Grant
    Filed: July 21, 2009
    Date of Patent: March 19, 2013
    Assignees: Otonomy, Inc., The Regents of The University of California
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris
  • METHODS FOR TREATING MILD COGNITIVE IMPAIRMENT
    Publication number: 20130059824
    Abstract: Provided herein are PAK inhibitors. Also provided herein are compositions and methods for treating an individual suffering from Mild Cognitive Impairment.
    Type: Application
    Filed: November 23, 2010
    Publication date: March 7, 2013
    Applicant: AFRAXis, Inc.
    Inventors: Jay Lichter, David Campbell, Benedikt Vollrath, Sergio G. Durón
  • 8-ethyl-6-(aryl)pyrido[2,3-D]pyrimidin-7(8H)-ones for the treatment of CNS disorders
    Patent number: 8372970
    Abstract: Provided herein are PAK inhibitors and methods of utilizing PAK inhibitors for the treatment of CNS disorders such as neuropsychiatric disorders.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: February 12, 2013
    Assignee: Afraxis, Inc.
    Inventors: Benedikt Vollrath, David Campbell, Sergio G. Durón, Warren Wade
  • PYRROLOPYRAZOLES FOR TREATING CNS DISORDERS
    Publication number: 20120283296
    Abstract: Provided herein are methods of utilizing PAK inhibitors for the treatment of CNS disorders.
    Type: Application
    Filed: October 6, 2010
    Publication date: November 8, 2012
    Applicant: aFRAXis, Inc.
    Inventors: David Campbell, Sergio G. Durón, Benedikt Vollrath
  • 8-ETHYL-6-(ARYL)PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS
    Publication number: 20120270866
    Abstract: Provided herein are PAK inhibitors and methods of utilizing PAK inhibitors for the treatment of CNS disorders such as neuropsychiatric disorders.
    Type: Application
    Filed: October 8, 2010
    Publication date: October 25, 2012
    Applicant: aFRAXis Inc.
    Inventors: Benedikt Vollrath, Daivd Campbell, Sergio G. Durón, Warren Wade
  • METHODS FOR TREATING ALZHEIMER'S DISEASE
    Publication number: 20120270844
    Abstract: Provided herein arc PAK inhibitors. Also provided herein are compositions and methods for treating an individual suffering from Alzheimer's disease.
    Type: Application
    Filed: October 8, 2010
    Publication date: October 25, 2012
    Applicant: aFRAXis, Inc.
    Inventors: Jay Lichter, Benedikt Vollrath, David Campbell, Sergio G. Durón
  • Controlled-Release CNS Modulating Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20120190671
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: March 20, 2012
    Publication date: July 26, 2012
    Applicants: The Regents of the University of California, Otonomy, Inc.
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris
  • METHODS FOR TREATING SCHIZOPHRENIA
    Publication number: 20120184547
    Abstract: Provided herein are PAK inhibitors. Also provided herein are compositions and methods for treating an individual suffering from schizophrenia.
    Type: Application
    Filed: July 16, 2010
    Publication date: July 19, 2012
    Applicant: aFRAXis, Inc.
    Inventors: Jay Lichter, David Campbell, Benedikt Vollrath, Sergio G. Durón
  • COMPOUNDS FOR TREATING NEUROPSYCHIATRIC CONDITIONS
    Publication number: 20120046283
    Abstract: Provided herein are PAK inhibitors and methods of utilizing PAK inhibitors for the treatment of neuropsychiatric conditions.
    Type: Application
    Filed: December 18, 2009
    Publication date: February 23, 2012
    Applicant: AFRAXIS INC.
    Inventors: David Campbell, Sergio G. Durón, Benedikt Vollrath, Warren Wade
  • Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20110319374
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 25, 2011
    Publication date: December 29, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, OTONOMY, INC.
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Durón, Michael Christopher Scaife, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Andrew M. Trammel, Jeffrey P. Harris
  • Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20110319375
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 25, 2011
    Publication date: December 29, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, OTONOMY, INC.
    Inventors: Jay Lichter, Benedikt Vollrath, Sergio G. Durón, Michael Christopher Scaife, Fabrice Piu, Qiang Ye, Luis A. Dellamary, Carl Lebel, Andrew M. Trammel, Jeffrey P. Harris
  • Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20110319377
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 25, 2011
    Publication date: December 29, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, OTONOMY, INC.
    Inventors: Jay Lichter, Benedikt Vollrath, Andrew M. Trammel, Sergio G. Durón, Fabrice Piu, Luis A. Dellamary, Qiang Ye, Carl Lebel, Michael Christopher Scaife, Jeffrey P. Harris
  • Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
    Publication number: 20110319373
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal, NSAID, and/or ATPase compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 25, 2011
    Publication date: December 29, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, OTONOMY, INC.
    Inventors: Jay Lichter, Benedikt Vollrath, Andrew M. Trammel, Sergio G. Durón, Fabrice Piu, Luis A. Dellamary, Qiang Ye, Carl Lebel, Michael Christopher Scaife, Jeffrey P. Harris
  • Sulfonyl-substituted bicyclic compounds as modulators of PPAR
    Patent number: 7915253
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: March 29, 2011
    Assignee: Kalypsys, Inc
    Inventors: Stewart A. Noble, Guy Oshiro, James W. Malecha, Cunxiang Zhao, Carmen K. Robinson, Sergio G. Duron, Michael Sertic, Andrew K. Lindstrom, Andrew K. Shiau, Christopher D. Bayne, Mehmet Kahraman, Boliang Lou, Steve P. Govek
  • METHODS FOR TREATING NEUROPSYCHIATRIC CONDITIONS
    Publication number: 20100317715
    Abstract: Provided herein are compositions and methods for treating a subject suffering from Fragile X syndrome, autism, Down's syndrome, mental retardation, or a neuropsychiatric condition (e.g., schizophrenia). The methods include systemic administration of a a therapeutically effective amount of a PAK inhibitor in combination with a Group I mGluR antagonist (e.g., an mGluR5 antagonist). The PAK inhibitor and mGluR antagonist can be administered together, e.g., in one pharmacological composition, or they can be administered separately.
    Type: Application
    Filed: December 19, 2008
    Publication date: December 16, 2010
    Inventors: Benedikt Vollrath, Jay Lichter, Sergio G. Duron, Petpiboon Peppi Prasit
  • Sulfonyl-substituted bicyclic compounds as modulators of PPAR
    Patent number: 7834004
    Abstract: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: November 16, 2010
    Assignee: Kalypsys, Inc
    Inventors: Stewart A. Noble, Guy Oshiro, James W. Malecha, Cunxiang Zhao, Carmen Robinson, Sergio G. Duron, Michael Sertic, Andrew K. Lindstrom, Andrew K. Shiau, Christopher D Bayne, Mehmet Kahraman, Boliang Lou, Steven P. Govek
  • CONTROLLED RELEASE ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100036000
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 20, 2009
    Publication date: February 11, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
  • CONTROLLED-RELEASE OTIC STRUCTURE MODULATING AND INNATE IMMUNE SYSTEM MODULATING COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS
    Publication number: 20100021416
    Abstract: Disclosed herein are compositions and methods for the treatment of otic disorders with otic structure modulating compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 20, 2009
    Publication date: January 28, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt VOLLRATH, Sergio G. DURON, Carl LEBEL, Fabrice PIU, Qiang YE, Luis A. DELLAMARY, Andrew M. TRAMMEL, Michael Christopher SCAIFE, Jeffrey P. HARRIS
  • CONTROLLED RELEASE COMPOSITIONS FOR MODULATING FREE-RADICAL INDUCED DAMAGE AND METHODS OF USE THEREOF
    Publication number: 20100022661
    Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
    Type: Application
    Filed: July 21, 2009
    Publication date: January 28, 2010
    Applicants: OTONOMY, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay LICHTER, Benedikt Vollrath, Sergio G. Duron, Carl Lebel, Febrice Plu, Qiang Ye, Luis A. DELLAMARY, Andrew M. Trammel, Michael Christopher Scaife, Jeffrey P. Harris