Patents by Inventor Sergio Merli

Sergio Merli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biosynthetic anthracyclines related to daunorubicin
    Patent number: 4942155
    Abstract: The novel compounds are provided with good antibacterial and antitumour activity.
    Type: Grant
    Filed: March 9, 1987
    Date of Patent: July 17, 1990
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Giuseppe Cassinelli, Arpad Grein, Sergio Merli, Giovanni Rivola
  • New antitumor agent obtained by microbial stereoselective reduction of 4'-deoxy-4'-iododoxorubicin
    Patent number: 4895933
    Abstract: 4'-Deoxy-13(S)-dihydro-4'-iododoxorubicin having the formula (II): ##STR1## and pharmaceutically acceptable salts thereof are anti-tumor agents.
    Type: Grant
    Filed: January 19, 1988
    Date of Patent: January 23, 1990
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Giuseppe Cassinelli, Teresa Bordoni, Sergio Merli, Giovanni Rivola
  • Antitumor antibiotics
    Patent number: 4421851
    Abstract: Anthracycline glycosides W, X, Y and Z which are prepared by the fermentation of mutant F.I. 416 of Streptomyces peucetius var. caesius. The new compounds are useful against both gram positive and gram negative bacteria and as antitumor agents.
    Type: Grant
    Filed: November 16, 1981
    Date of Patent: December 20, 1983
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Giuseppe Cassinelli, Arpad Grein, Sergio Merli, Giovanni Rivola
  • Preparation of II-deoxy anthracycline antibiotics
    Patent number: 4411834
    Abstract: Anthracycline antibiotics of the formula: ##STR1## wherein R is --CO--CH.sub.2 OH, --CHOH--CH.sub.3, --CO--CH.sub.3 or --CH.sub.2 --CH.sub.3 having antitumor and antibacterial activity are prepared by culturing a new mutant strain of microorganism designated as Micromonospora peucetica sp. nova and which has been deposited with the American Type Culture Collection under number No. 31366 ATCC.
    Type: Grant
    Filed: September 2, 1981
    Date of Patent: October 25, 1983
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Giuseppe Cassinelli, Arpad Grein, Sergio Merli, Giovanni Rivola
  • 11-Deoxy-carminomycin compounds
    Patent number: 4370474
    Abstract: Anthracycline glycosides W, X, Y and Z which are prepared by the fermentation of mutant F.I. 416 of Streptomyces peucetius var. caesius. The new compounds are useful against both gram positive and gram negative bacteria and as antitumor agents.
    Type: Grant
    Filed: November 15, 1979
    Date of Patent: January 25, 1983
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Giuseppe Cassinelli, Arpad Grein, Sergio Merli, Giovanni Rivola
  • Preparation of 11-deoxy anthracycline antibiotics
    Patent number: 4309503
    Abstract: Anthracycling antibiotics of the formula: ##STR1## wherein R is --CO--CH.sub.2 OH, --CHOH--CH.sub.3, --CO--CH.sub.3 or --CH.sub.2 --CH.sub.3 having antitumor and antibacterial activity are prepared by culturing a new mutant strain of microorganism designated as Macromonospora peucetica sp. nova and which has been deposited with the American Type Culture Collection under numbr No. 31366 ATCC.
    Type: Grant
    Filed: October 5, 1979
    Date of Patent: January 5, 1982
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Giuseppe Cassinelli, Arpad Grein, Sergio Merli, Giovanni Rivola
  • 11-Deoxy anthracycline antibiotics, their preparation and use
    Patent number: 4247545
    Abstract: Anthracycline antibiotics of the formula: ##STR1## wherein R is --CO--CH.sub.2 OH, --CHOH--CH.sub.3, --CO--CH.sub.3 or --CH.sub.2 --CH.sub.3 having antitumor and antibacterial activity are prepared by culturing a new mutant strain of microorganism designated as Micromonospora peucetica sp. nova and which has been deposited with the American Type Culture Collection under number No. 31366 ATCC.
    Type: Grant
    Filed: February 5, 1979
    Date of Patent: January 27, 1981
    Inventors: Giuseppe Cassinelli, Arpad Grein, Sergio Merli, Giovanni Rivola