Patents by Inventor Serjan D. Nikolic
Serjan D. Nikolic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10307147Abstract: Partitioning devices that may be secured and sealed within a heart chamber for separating a patient's heart chamber into a productive portion and a non-productive portion are described herein. The partitioning devices described herein may include a membrane with a plurality of inflatable elements. The membrane may include a valve disposed in a central region of the membrane with a plurality of inflation channels extending radially from the valve. These devices may be secured within the heart chamber by sealing them to the wall of the heart chamber, for example, by inflating the plurality of inflatable elements on the periphery of the device. The non-productive portion may be filled with a material, including occlusive materials. Sealing and/or filling the non-productive portion formed by the devices described herein may help prevent leakage from the non-productive region.Type: GrantFiled: March 7, 2017Date of Patent: June 4, 2019Assignee: Edwards Lifesciences CorporationInventors: Alexander Khairkhahan, Serjan D. Nikolic, Hugh R. Sharkey
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Patent number: 10307253Abstract: Partitioning devices that may be secured and sealed within a heart chamber for separating a patient's heart chamber into a productive portion and a non-productive portion are described herein. The partitioning devices described herein may include a reinforced membrane with outwardly biased members. The reinforced membrane may have a central hub with a distally extending support stem with a plurality of feet which extend radially from a centerline axis and preferably have ends that are aligned in a common plane. These devices may be secured within the heart chamber by sealing them to the wall of the heart chamber, for example, by inflating an inflatable element on the periphery of the device. The non-productive portion may be filled with a material, including occlusive materials. Sealing and/or filling the non-productive portion formed by the devices described herein may help prevent leakage from the non-productive region.Type: GrantFiled: February 21, 2013Date of Patent: June 4, 2019Assignee: Edwards Lifesciences CorporationInventors: Alexander Khairkhahan, Serjan D. Nikolic, Hugh R. Sharkey
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Patent number: 10251750Abstract: A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.Type: GrantFiled: June 22, 2017Date of Patent: April 9, 2019Assignee: Edwards Lifesciences CorporationInventors: Miles D. Alexander, Matthew L. Pease, Barry L. Templin, Serjan D. Nikolic
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Patent number: 10064696Abstract: Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.Type: GrantFiled: April 19, 2016Date of Patent: September 4, 2018Inventors: Michael P. Boutillette, James R. Kermode, Miles D. Alexander, Alexander Khairkhahan, Serjan D. Nikolic
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Publication number: 20170290664Abstract: A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.Type: ApplicationFiled: June 22, 2017Publication date: October 12, 2017Inventors: Miles D. ALEXANDER, Matthew L. PEASE, Barry L. TEMPLIN, Serjan D. NIKOLIC
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Patent number: 9694121Abstract: A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.Type: GrantFiled: February 25, 2014Date of Patent: July 4, 2017Assignee: CardioKinetix, Inc.Inventors: Miles D. Alexander, Matthew L. Pease, Barry L Templin, Serjan D. Nikolic
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Publication number: 20170172742Abstract: Partitioning devices that may be secured and sealed within a heart chamber for separating a patient's heart chamber into a productive portion and a non-productive portion are described herein. The partitioning devices described herein may include a membrane with a plurality of inflatable elements. The membrane may include a valve disposed in a central region of the membrane with a plurality of inflation channels extending radially from the valve. These devices may be secured within the heart chamber by sealing them to the wall of the heart chamber, for example, by inflating the plurality of inflatable elements on the periphery of the device. The non-productive portion may be filled with a material, including occlusive materials. Sealing and/or filling the non-productive portion formed by the devices described herein may help prevent leakage from the non-productive region.Type: ApplicationFiled: March 7, 2017Publication date: June 22, 2017Inventors: Alexander KHAIRKHAHAN, Serjan D. NIKOLIC, Hugh R. SHARKEY
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Patent number: 9592123Abstract: Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.Type: GrantFiled: July 31, 2014Date of Patent: March 14, 2017Assignee: CardioKinetix, Inc.Inventors: Serjan D. Nikolic, Alexander Khairkhahan
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Publication number: 20160302924Abstract: Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.Type: ApplicationFiled: April 19, 2016Publication date: October 20, 2016Inventors: Michael P. BOUTILLETTE, James R. KERMODE, Miles D. ALEXANDER, Alexander KHAIRKHAHAN, Serjan D. NIKOLIC
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Publication number: 20150265405Abstract: Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.Type: ApplicationFiled: June 4, 2015Publication date: September 24, 2015Inventors: Michael P. BOUTILLETTE, James R. KERMODE, Miles D. ALEXANDER, Alexander KHAIRKHAHAN, Serjan D. NIKOLIC
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Patent number: 9078660Abstract: Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.Type: GrantFiled: September 29, 2010Date of Patent: July 14, 2015Assignee: CardioKinetix, Inc.Inventors: Michael P. Boutillette, James R. Kermode, Miles D. Alexander, Alexander Khairkhahan, Serjan D. Nikolic
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Publication number: 20140343356Abstract: Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.Type: ApplicationFiled: July 31, 2014Publication date: November 20, 2014Inventors: Serjan D. NIKOLIC, Alexander KHAIRKHAHAN
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Patent number: 8827892Abstract: Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.Type: GrantFiled: August 22, 2013Date of Patent: September 9, 2014Assignee: CardioKinetix, Inc.Inventors: Serjan D. Nikolic, Alexander Khairkhahan
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Publication number: 20140179993Abstract: A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.Type: ApplicationFiled: February 25, 2014Publication date: June 26, 2014Inventors: Miles D. ALEXANDER, Matthew L. PEASE, Barry L TEMPLIN, Serjan D. NIKOLIC
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Patent number: 8747454Abstract: A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge.Type: GrantFiled: May 7, 2007Date of Patent: June 10, 2014Assignee: CardioKinetix, Inc.Inventors: Alexander Khairkhahan, Hugh R. Sharkey, Serjan D. Nikolic
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Patent number: 8672827Abstract: Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.Type: GrantFiled: January 21, 2010Date of Patent: March 18, 2014Assignee: CardioKinetix, Inc.Inventors: Serjan D. Nikolic, Alexander Khairkhahan
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Patent number: 8657873Abstract: A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge.Type: GrantFiled: May 7, 2007Date of Patent: February 25, 2014Assignee: CardioKinetix, Inc.Inventors: Alexander Khairkhahan, Hugh R. Sharkey, Serjan D. Nikolic
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Publication number: 20130338695Abstract: Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.Type: ApplicationFiled: August 22, 2013Publication date: December 19, 2013Inventors: Serjan D. NIKOLIC, Alexander KHAIRKHAHAN
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Patent number: 8529430Abstract: Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.Type: GrantFiled: May 29, 2008Date of Patent: September 10, 2013Assignee: CardioKinetix, Inc.Inventors: Serjan D. Nikolic, Alexander Khairkhahan
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Patent number: 8500795Abstract: Removable cardiac implants, applicators for inserting, repositioning and/or removing them, and methods of using them are described. In particular, removable or repositionable ventricular partitioning devices are described. Systems including removable implants and applicators for inserting and/or removing them are also described.Type: GrantFiled: August 25, 2008Date of Patent: August 6, 2013Assignee: CardioKinetix, Inc.Inventors: Alexander Khairkhahan, Serjan D. Nikolic, Hugh R. Sharkey