Abstract: An actuation assembly for a tissue recruiting device for recruiting tissue and closing a defect. The actuation assembly includes one or more control actuators operable to control the position and rotation of an actuation element coupled to a grasping device. The grasping device is configured to grasp tissue. The actuation assembly is operable by a user to deploy the grasping device via the actuation element to grasp tissue. The actuation assembly may independently deploy multiple grasping devices, such as on opposite sides of a defect. The actuation assembly may also deploy a closure mechanism configured to circumferentially surround the deployed grasping devices to close the defect.

Abstract: A tissue recruiting device for treating and closing a defect and methods of using the same. The tissue recruiting device includes a tissue recruiting assembly with two grasping devices and a shroud. An actuation assembly couples control actuators to the grasping devices via actuation elements. The grasping devices may be maneuvered to grasp tissue from different locations by actuation of the control actuators. The grasping devices may be retracted into a shroud to substantially close the defect. The grasping devices and the shroud may be decoupled from the remainder of the tissue recruiting assembly to maintain closure of the defect.

Abstract: A tissue clipping device for clipping tissue and methods of using the same. The device includes a tissue clipping assembly for clipping tissue and a drive assembly operable to control the operation of the tissue clipping assembly. The tissue clipping assembly includes a distal arm that is linearly extendable and retractable to clip tissue. The tissue clipping assembly may be decoupled from the drive assembly after tissue is clipped. Additional clipping assemblies may be deployed with the drive assembly to close larger defects.

Abstract: A tissue recruiting device for treating and closing a defect and methods of using the same. The grasping device includes a grasping portion and a coupling portion. The grasping portion includes a plurality of helical coils. The coupling portion is operably coupled with an actuation element. An actuation assembly is operable to translate and rotate the actuation element such that the grasping device pierces into and grasps target tissue.

Abstract: An endoscopic resection assembly includes an adaptor configured to adapt to an endoscopic device. A pusher is disposed on the adaptor by inserting the adaptor into the central opening defined by the pusher. A cutting device includes a snare loop and a snare drive cable, and is removably coupled to the pusher. The cutting device is configured to resect a tissue when the snare loop is contracted by activation of the snare driver. A clip for engaging onto the tissue can be loaded onto the adaptor at a position distal to the pusher.

Abstract: An endoscopic resection assembly includes an adaptor configured to adapt to an endoscopic device. A pusher is disposed on the adaptor by inserting the adaptor into the central opening defined by the pusher. A cutting device includes a snare loop and a snare drive cable, and is removably coupled to the pusher. The cutting device is configured to resect a tissue when the snare loop is contracted by activation of the snare driver. A clip for engaging onto the tissue can be loaded onto the adaptor at a position distal to the pusher.