Abstract: The present invention relates to a method for prenatal diagnosis using digital PCR, and more particularly to a method for providing information for diagnosis of chromosomal aneuploidy in a fetus, comprising: (a) extracting DNAs from pregnant woman's blood; (b) classifying the DNAs according to size to obtain DNAs having a size of 1,000 bp or less; (c) performing digital PCR using the obtained DNAs of step (b), for a control gene located on a chromosome not associated with chromosomal aneuploidy and a target gene located on a chromosome associated with chromosomal aneuploidy; (d) calculating a ratio of a quantitative digital PCR value of the target gene to a quantitative digital PCR value of the control gene; and (e) determining that when the ratio calculated in step (d) is 0.70-1.14, a chromosome number of the fetus is normal.

Abstract: Provided is a mixed reality-based experience simulator including an imaging part including first and second cameras installed on an experience object to capture images of different viewpoints from the experience object, a display part worn by a participant and configured to display a mixed reality image of the experience object to the participant, and an image processing unit configured to provide the mixed reality image to the display part and configured to generate the mixed reality image such that images captured by the first and second cameras are included in the mixed reality image. The mixed reality-based experience simulator according to the present invention generates a mixed reality image on the basis of images captured by a plurality of cameras installed on an experience object and provides the generated mixed reality image to a participant so that a more realistic experience is provided.

Abstract: A gravure printing plate includes a convex portion and two or more polygonal cells partitioned by the convex portion, and including at least one protruding portion disposed at an edge of each of the at least two polygonal cells and extending toward a central portion of the corresponding cell therefrom.

Abstract: A method of identifying potential lesions in mammographic images may include operations executed by an image processing device including receiving first image data of a first type, receiving second image data of a second type, registering the first image data and the second image data by employing a CNN using pixel level registration or object level registration, determining whether a candidate detection of a lesion exists in both the first image data and the second image data based on the registering of the first image data and the second image data, and generating display output identifying the lesion.

Abstract: A semi-submersible marine structure is described. The structure includes a hull including a pontoon, a deck disposed above the pontoon, and a plurality of columns supporting the deck from the pontoon. The structure also includes a plurality of tendons supporting the hull from a seabed. The pontoon has the shape of a circular ring, and the plurality of tendons are arranged at regular intervals along an external circumferential surface of the pontoon.

Abstract: The present invention relates to a method for prenatal diagnosis using digital PCR, and more particularly to a method for providing information for diagnosis of chromosomal aneuploidy in a fetus, comprising: (a) extracting DNAs from pregnant woman's blood; (b) classifying the DNAs according to size to obtain DNAs having a size of 1,000 bp or less; (c) performing digital PCR using the obtained DNAs of step (b), for a control gene located on a chromosome not associated with chromosomal aneuploidy and a target gene located on a chromosome associated with chromosomal aneuploidy; (d) calculating a ratio of a quantitative digital PCR value of the target gene to a quantitative digital PCR value of the control gene; and (e) determining that when the ratio calculated in step (d) is 0.70-1.14, a chromosome number of the fetus is normal.

Abstract: A semi-submersible marine structure is described. The structure includes a hull including a pontoon, a deck disposed above the pontoon, and a plurality of columns supporting the deck from the pontoon. The structure also includes a plurality of tendons supporting the hull from a seabed. The pontoon has the shape of a circular ring, and the plurality of tendons are arranged at regular intervals along an external circumferential surface of the pontoon.

Abstract: A pattern wheel driver is provided. The pattern wheel driver includes a rotatable pattern wheel with patterned regions repeatedly formed on the pattern wheel. Each of the patterned regions has a plurality of patterns. Each of the plurality of patterns has a different width. The pattern wheel driver also includes a detector for detecting the plurality of patterns, mounted at a position where the patterned regions of the pattern wheel pass when the pattern wheel rotates. The pattern wheel driver also includes an encoder for producing a signal indicating whether the pattern wheel rotates in a forward direction or a reverse direction based on signals produced by the detector.

Abstract: Provided are a solar cell and a method of manufacturing the same. The method of manufacturing the solar cell includes stacking a solar cell device layer containing GaN on a sacrificial substrate, etching the solar cell device layer to expose the sacrificial substrate, thereby forming one or more solar cell devices comprising the solar cell device layer, anisotropically etching the exposed sacrificial substrate, contacting the solar cell devices to a stamping processor to remove the solar cell devices from the sacrificial substrate, and transferring the solar cell devices onto a receiving substrate. A high temperature semiconductor process may be performed on a substrate such as a silicon substrate to transfer the solar cell devices onto the substrate, thereby manufacturing flexible solar cells. Also, a large number of solar cells may be excellently aligned on a large area. In addition, economical solar cells may be manufactured.

Abstract: Provided are a phase-change memory device using insulating nanoparticles, a flexible phase-change memory device and a method for manufacturing the same. The phase-change memory device includes an electrode, and a phase-change layer in which a phase change occurs depending on heat generated from the electrode, wherein insulating nanoparticles formed from a self-assembled block copolymer are provided between the electrode and the phase-change layer undergoing crystallization and amorphization.

Abstract: Provided are a solar cell and a method of manufacturing the same. The method of manufacturing the solar cell includes stacking a solar cell device layer containing GaN on a sacrificial substrate, etching the solar cell device layer to expose the sacrificial substrate, thereby forming one or more solar cell devices comprising the solar cell device layer, anisotropically etching the exposed sacrificial substrate, contacting the solar cell devices to a stamping processor to remove the solar cell devices from the sacrificial substrate, and transferring the solar cell devices onto a receiving substrate. A high temperature semiconductor process may be performed on a substrate such as a silicon substrate to transfer the solar cell devices onto the substrate, thereby manufacturing flexible solar cells. Also, a large number of solar cells may be excellently aligned on a large area. In addition, economical solar cells may be manufactured.

Abstract: A method of manufacturing LED display is provided. The method provides a sacrificial substrate on which RGB LED device layers are formed, respectively. The method etches and patterns the LED device layer to manufacture RGB LED devices, respectively. The method removes the sacrificial substrate in a lower side of the LED device. The method contacts a stamping processor to the RGB LED devices to separate the RGB LED devices from the sacrificial substrate. The method transfers the LED device, which is attached to the stamping processor, to a receiving substrate.

Abstract: Provided are a phase-change memory device using insulating nanoparticles, a flexible phase-change memory device and a method for manufacturing the same. The phase-change memory device includes an electrode, and a phase-change layer in which a phase change occurs depending on heat generated from the electrode, wherein insulating nanoparticles formed from a self-assembled block copolymer are provided between the electrode and the phase-change layer undergoing crystallization and amorphization.

Abstract: Disclosed herein are rhodanine derivatives, a method for the preparation thereof, and a pharmaceutical composition containing the same. The rhodanine derivatives have inhibitory activity against protein phosphatases (PPase) such as PTP1B, Prl-3, LAR, CD45, Cdc25A, Cdc25B, Cdc25C, Yop, PP1 and VHR, and can be applied for the prevention and treatment of PPase-caused diseases, including autoimmune diseases, diabetes, impaired glucose intolerance, insulin resistance, obesity, cancers, etc. when the inhibitory activity thereof is modulated.

Abstract: The present invention relates to a crystal structure of PRL-1 (Phospatase of Regenerating Liver) protein and a method of crystallization thereof. It has been found that the PRL-1 protein has a tertiary structure having 5 strands of beta-sheet surrounded by 6 alpha-helices and well-arranged active site with closed P-loop, and monomers form a trimer through farnesylation site in the C-terminus of said protein. Thus intra-cellular migration and membrane localization can be achieved. The said crystal structure of PRL-1 protein of the present invention is very useful for the development the agent which inhibits carcinogenesis and metastasis of the cancer.

Abstract: An optimal resource allocation strategy for OFDMA multi-hop wireless networks is disclosed. The system allocates one or more resources in a multi-hop network by solving one or more higher-layer sub-problem; solving one or more physical layer and media access control (PHY/MAC) layer sub-problems per tone per time slot with one of cooperative relaying of radio signals or spatial reusing of radio spectrum; updating prices; and allocating radio resources based on the PHY/MAC layer sub-problems.

Abstract: Provided are a solar cell and a method of manufacturing the same. The method of manufacturing the solar cell includes stacking a solar cell device layer containing GaN on a sacrificial substrate, etching the solar cell device layer to expose the sacrificial substrate, thereby forming one or more solar cell devices comprising the solar cell device layer, anisotropically etching the exposed sacrificial substrate, contacting the solar cell devices to a stamping processor to remove the solar cell devices from the sacrificial substrate, and transferring the solar cell devices onto a receiving substrate. A high temperature semiconductor process may be performed on a substrate such as a silicon substrate to transfer the solar cell devices onto the substrate, thereby manufacturing flexible solar cells. Also, a large number of solar cells may be excellently aligned on a large area. In addition, economical solar cells may be manufactured.

Abstract: A method of manufacturing LED display is provided. The method provides a sacrificial substrate on which RGB LED device layers are formed, respectively. The method etches and patterns the LED device layer to manufacture RGB LED devices, respectively. The method removes the sacrificial substrate in a lower side of the LED device. The method contacts a stamping processor to the RGB LED devices to separate the RGB LED devices from the sacrificial substrate. The method transfers the LED device, which is attached to the stamping processor, to a receiving substrate.

Abstract: Provided are a flexible biosensor using a gold binding substance and a method for manufacturing the same. The flexible biosensor includes: a flexible substrate; a silicon substrate which is formed on the flexible substrate and on which source and drain regions doped with a first type impurity are formed with a predetermined gap; and source, drain and gate electrodes which are formed on the silicon substrate and comprise gold, wherein, on the gate electrode, a fused protein which is formed by fusion with a gold binding substance specifically binding to gold is immobilized. Since the biosensor is embodied on a flexible substrate, it may effectively overcome the limitation of the existing biosensor embodied on a silicon substrate.

Abstract: The present invention relates to protein tyrosine phosphatase (PTP) and a method for preparing the same, precisely, a method for expressing PTP active domain with high activity and stability without help of a fusion protein, by using computer based protein structure prediction technique. PTP prepared by the method of the present invention can be effectively used as a protein for high efficiency drug screening for the development of a novel drug, as an antigen protein for the construction of a selective antibody and as a protein for the studies of PTP structure and functions.