Abstract: An endotracheal tube comprises a main lumen for delivering a breathing gas into a lung of a patient, and a cuff, mounted at a distal end of the endotracheal tube, to be located in the subglottal region of the patient. The endotracheal tube also comprises a cuff inflation lumen for inflating the cuff, and at least three additional lumens, other than the main lumen and the cuff inflation lumen, configured for delivering liquid to the subglottal region, for suctioning liquid from the subglottal region, and for venting the subglottal region.

Abstract: A system for controlling and monitoring flow in a cuffed endotracheal tube device is disclosed. The system comprises: a connector panel having at least three connectors adapted for establishing fluid communication with proximal ends of at least a first fluid line, a second fluid line and a cuff inflation line of the endotracheal tube device. The system can further comprise a processing unit and a control unit, wherein the processing unit is configured to instruct the control unit to execute various operations, including at least a rinsing procedure, a suctioning procedure, a cuff inflation procedure, a leak detection procedure and a venting procedure, and to select any of the first and the second fluid lines for any of the rinsing, suctioning, leak detection and venting procedures. In some embodiments, the system exploits the cuff as sensor to sense pulmonary data.

Abstract: A system for controlling and monitoring flow in a cuffed endotracheal tube device is disclosed. The system comprises: a connector panel having at least three connectors adapted for establishing fluid communication with proximal ends of at least a first fluid line, a second fluid line and a cuff inflation line of the endotracheal tube device. The system can further comprise a processing unit and a control unit, wherein the processing unit is configured to instruct the control unit to execute various operations, including at least a rinsing procedure, a suctioning procedure, a cuff inflation procedure, a leak detection procedure and a venting procedure, and to select any of the first and the second fluid lines for any of the rinsing, suctioning, leak detection and venting procedures. In some embodiments, the system exploits the cuff as sensor to sense pulmonary data.

Abstract: A system for controlling and monitoring flow in a cuffed endotracheal tube device is disclosed. The system comprises: a connector panel having at least three connectors adapted for establishing fluid communication with proximal ends of at least a first fluid line, a second fluid line and a cuff inflation line of the endotracheal tube device. The system can further comprise a processing unit and a control unit, wherein the processing unit is configured to instruct the control unit to execute various operations, including at least a rinsing procedure, a suctioning procedure, a cuff inflation procedure, a leak detection procedure and a venting procedure, and to select any of the first and the second fluid lines for any of the rinsing, suctioning, leak detection and venting procedures. In some embodiments, the system exploits the cuff as sensor to sense pulmonary data.

Abstract: In an alerting and controlling system, there is a measuring device and a controller. The measuring device is connectable to an endotracheal tube associated with a cuff inflatable below the vocal cords of a subject, for measuring at least one measure being indicative of the presence of leakage of secretions from above the cuff to the lungs of the subject. The controller adjusts inflation of the cuff responsively to the level of the at least one measure such as to reduce or prevent leakage of secretions from above the cuff to the lungs, and alerts that the endotracheal tube is malpositioned in the airway of the subject if an inflation pressure of the cuff exceeds a predetermined threshold.

Abstract: An endotracheal tube comprises a main lumen for delivering a breathing gas into a lung of a patient, and a cuff, mounted at a distal end of the endotracheal tube, to be located in the subglottal region of the patient. The endotracheal tube also comprises a cuff inflation lumen for inflating the cuff, and at least three additional lumens, other than the main lumen and the cuff inflation lumen, configured for delivering liquid to the subglottal region, for suctioning liquid from the subglottal region, and for venting the subglottal region.

Abstract: An endotracheal tube for mechanically ventilating patients is disclosed. The endotracheal tube comprises a distal end for insertion into the patient's airway, past the vocal chords, through the subglottal region, and into the patient's lung; and a proximal end for connection to a mechanical ventilator. The endotracheal tube further comprises a cuff at the distal end of the endotracheal tube to be located in the subglottal region of the patient below the vocal chords, an inflating lumen for inflating the cuff, and a suction lumen having a suction inlet port leading from the outer surface of the endotracheal tube, and to be located in the subglottal region, for evacuating secretions and/or rinsing fluid from the subglottal region during the mechanical ventilation of the patient.

Abstract: A method of monitoring tracheal pressure of a subject is disclosed. The subject is ventilated with breathing gas flowing via an endotracheal tube having an inflatable cuff. The method comprises monitoring sealing of the trachea by the cuff using a close loop control, varying a ventilation pressure thereby varying flow level of the breathing gas, monitoring a response pressure within the cuff in response to the variation, and calculating the tracheal pressure using the ventilation pressure variations, the cuff response pressure and the flow level. In some embodiments, an under-pressure is applied for suctioning fluid carrying secretions, synchronously with variations in the tracheal pressure.

Abstract: A method of intubating a subject is disclosed. The method comprises inserting an endotracheal tube into the tracheal airway of the subject; inflating a cuff associated with the endotracheal tube within the airway below the vocal cords; measuring a level of at least one measure being indicative of leakage of secretion past the cuff to the lungs; comparing the level of the measure with an optimal level of the measure; and adjusting inflation of the cuff based on the comparison so as to generally minimize leakage of secretion from above the cuff to the lungs, while minimizing pressure associated damages to the airway. The measure(s) can be carbon dioxide concentration, a proxy measure from which such concentration can be inferred, or the level of one or more additives delivered to a subject during intubation.

Abstract: A method of intubating a subject is disclosed. The method comprises inserting an endotracheal tube into the tracheal airway of the subject; inflating a cuff associated with the endotracheal tube within the airway below the vocal cords; measuring a level of at least one measure being indicative of leakage of secretion past the cuff to the lungs; comparing the level of the measure with an optimal level of the measure; and adjusting inflation of the cuff based on the comparison so as to generally minimize leakage of secretion from above the cuff to the lungs, while minimizing pressure associated damages to the airway. The measure(s) can be carbon dioxide concentration, a proxy measure from which such concentration can be inferred, or the level of one or more additives delivered to a subject during intubation.

Abstract: A system for controlling and monitoring flow in a cuffed endotracheal tube device is disclosed. The system comprises: a connector panel having at least three connectors adapted for establishing fluid communication with proximal ends of at least a first fluid line, a second fluid line and a cuff inflation line of the endotracheal tube device. The system can further comprise a processing unit and a control unit, wherein the processing unit is configured to instruct the control unit to execute various operations, including at least a rinsing procedure, a suctioning procedure, a cuff inflation procedure, a leak detection procedure and a venting procedure, and to select any of the first and the second fluid lines for any of the rinsing, suctioning, leak detection and venting procedures. In some embodiments, the system exploits the cuff as sensor to sense pulmonary data.

Abstract: A method of intubating a subject is disclosed. The method comprises inserting an endotracheal tube into the tracheal airway of the subject; inflating a cuff associated with the endotracheal tube within the airway below the vocal cords; measuring a level of at least one measure being indicative of leakage of secretion past the cuff to the lungs; comparing the level of the measure with an optimal level of the measure; and adjusting inflation of the cuff based on the comparison so as to generally minimize leakage of secretion from above the cuff to the lungs, while minimizing pressure associated damages to the airway. The measure(s) can be carbon dioxide concentration, a proxy measure from which such concentration can be inferred, or the level of one or more additives delivered to a subject during intubation.

Abstract: A method of monitoring tracheal pressure of a subject is disclosed. The subject is ventilated with breathing gas flowing via an endotracheal tube having an inflatable cuff. The method comprises monitoring sealing of the trachea by the cuff using a close loop control, varying a ventilation pressure thereby varying flow level of the breathing gas, monitoring a response pressure within the cuff in response to the variation, and calculating the tracheal pressure using the ventilation pressure variations, the cuff response pressure and the flow level. In some embodiments, an under-pressure is applied for suctioning fluid carrying secretions, synchronously with variations in the tracheal pressure.

Abstract: A method of intubating a subject is disclosed. The method comprises inserting an endotracheal tube into the tracheal airway of the subject; inflating a cuff associated with the endotracheal tube within the airway below the vocal cords; measuring a level of at least one measure being indicative of leakage of secretion past the cuff to the lungs; comparing the level of the measure with an optimal level of the measure; and adjusting inflation of the cuff based on the comparison so as to generally minimize leakage of secretion from above the cuff to the lungs, while minimizing pressure associated damages to the airway. The measure(s) can be carbon dioxide concentration, a proxy measure from which such concentration can be inferred, or the level of one or more additives delivered to a subject during intubation.

Abstract: A method of intubating a subject is disclosed. The method comprises inserting an endotracheal tube into the tracheal airway of the subject; inflating a cuff associated with the endotracheal tube within the airway below the vocal cords; measuring a level of at least one measure being indicative of leakage of secretion past the cuff to the lungs; comparing the level of the measure with an optimal level of the measure; and adjusting inflation of the cuff based on the comparison so as to generally minimize leakage of secretion from above the cuff to the lungs, while minimizing pressure associated damages to the airway. The measure(s) can be carbon dioxide concentration, a proxy measure from which such concentration can be inferred, or the level of one or more additives delivered to a subject during intubation.

Abstract: An endotracheal tube for mechanically ventilating patients is disclosed. The endotracheal tube comprises a distal end for insertion into the patient's airway, past the vocal chords, through the subglottal region, and into the patient's lung; and a proximal end for connection to a mechanical ventilator. The endotracheal tube further comprises a cuff at the distal end of the endotracheal tube to be located in the subglottal region of the patient below the vocal chords, an inflating lumen for inflating the cuff, and a suction lumen having a suction inlet port leading from the outer surface of the endotracheal tube, and to be located in the subglottal region, for evacuating secretions and/or rinsing fluid from the subglottal region during the mechanical ventilation of the patient.

Abstract: An intubation method and system including the insertion of an endotracheal tube into a patient airway, inflating an cuff associated with the endotracheal tube at a location in the patient airway below the vocal cords, monitoring carbon dioxide concentration in the patient airway at a carbon dioxide monitoring location between the cuff and the vocal cords and adjusting inflation of the cuff based at least in part on the monitoring in order that the cuff inflation generally prevents leakage of carbon dioxide past the cuff.

Abstract: An intubation method and system including the insertion of an endotracheal tube into a patient airway, inflating an cuff associated with the endotracheal tube at a location in the patient airway below the vocal cords, monitoring carbon dioxide concentration in the patient airway at a carbon dioxide monitoring location between the cuff and the vocal cords and adjusting inflation of the cult based at least in part on the monitoring in order that the cuff inflation generally prevents leakage of carbon dioxide past the cuff.