Patents by Inventor Sham N. Redkar
Sham N. Redkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7683042Abstract: A stabilized glucosamine base composition comprising a glucosamine base having a purity level of at least 99.0 wt. % and a maximum halide content of about 0.01 wt. % coated with at least one pharmaceutically acceptable polymer comprising a water-soluble, water-immiscible and/or water-swellable homopolymer and/or copolymer. The resultant coated glucosamine base composition will be stable at ambient temperatures and upon exposure to the atmosphere. Suitable polymers include carboxypolymethylene homopolymers and copolymers; polyethylene glycol homopolymers and copolymers; polypropylene glycol homopolymers and copolymers; ethylcellulose; povidone homopolymers and copolymers; polyacrylic acid homopolymers and copolymers; polyacrylamide homopolymers and copolymers; polysaccharides; and mixtures of two or more of the foregoing polymers.Type: GrantFiled: September 9, 2005Date of Patent: March 23, 2010Assignee: JFC Technologies, LLCInventors: Vilas M. Chopdekar, Sham N. Redkar
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Patent number: 7622576Abstract: A glucosamine base having a pure level of at least about 99.0 wt. % and a maximum halide content of 0.01 wt. %. The pure glucosamine base is prepared by reacting a glucosamine halide, e.g., glucosamine hydrochloride, with a lithium base in the presence of a C1-C4 alcohol to thereby generate a C1-C4 alcohol solution of a lithium halide and an insoluble halide-free glucosamine base and thereafter separating the insoluble halide-free glucosamine base from the C1-C4 alcohol solution of the lithium halide. Preferably, the lithium base comprises anhydrous lithium hydroxide and the preferable alcohol comprises methanol.Type: GrantFiled: September 9, 2005Date of Patent: November 24, 2009Assignee: JFC Technologies, LLCInventors: Vilas M. Chopdekar, Sham N. Redkar
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Patent number: 7511134Abstract: A method for preparing n-acetylglucosamine starting from glucosamine base having a purity level of at least about 99 wt. % and a maximum halide content of about 0.01 wt %. The glucosamine base is slurried in a diluent comprising a C1-C4 straight or branched-chain alcohol, e.g., isopropyl alcohol, sec. butyl alcohol, tert. butyl alcohol, etc. Thereafter, an acylating agent, e.g., acetic anhydride, present in at least a stoichiometric amount, is slowly added to the slurry while maintaining the reaction mixture at a temperature below about 20° C. The n-acetylglucosamine prepared by the process of the invention will be quite pure, e.g., it will have a purity of at least 98%, as measured by HPLC, a melting point in the range of 196-205° C. and a specific rotation, measured at room temperature after standing in water for several hours, of [?]D=39-43°.Type: GrantFiled: September 9, 2005Date of Patent: March 31, 2009Assignee: JFC TechnologiesInventors: Sham N. Redkar, Vilas M. Chopdekar
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Patent number: 7388001Abstract: Glucosamine sulfate having a purity of at least about 99 wt. %, and a maximum halide content of about 0.01 wt. %. Preferably, the glucosamine sulfate is stabilized by coating it with at least one pharmaceutically acceptable polymer comprising a water-soluble, water-immiscible and/or water-swellable homopolymer and/or copolymer. Suitable polymers include carboxypolymethylene homopolymers and copolymers; polyethylene glycol homopolymers and copolymers; polypropylene glycol homopolymers and copolymers; ethylcellulose; povidone homopolymers and copolymers; polyacrylic acid homopolymers and copolymers; polyacrylamide homopolymers and copolymers; polysaccharides; and mixtures of two or more of the foregoing polymers. The resultant coated glucosamine sulfate composition will be stable at ambient temperatures and upon exposure to the atmosphere.Type: GrantFiled: September 9, 2005Date of Patent: June 17, 2008Assignee: JFC Technolries, LLCInventors: Vilas M. Chopdekar, Michelle Y. McGough, Hemant S. Desai, James G. Schleck, Sham N. Redkar
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Patent number: 7388000Abstract: Glucosamine phosphate having a purity of at least about 99 wt. %, and a maximum halide content of about 0.01 wt. %. Preferably, the glucosamine phosphate is stabilized by coating it with at least one pharmaceutically acceptable polymer comprising a water-soluble, water-immiscible and/or water-swellable homopolymer and/or copolymer. Suitable polymers include carboxypolymethylene hompolymers and copolymers; polyethylene glycol homopolymers and copolymers; polypropylene glycol homopolymers and copolymers; ethylcellulose; povidone homopolymers and copolymers; polyacrylic acid homopolymers and copolymers; polyacrylamide homopolymers and copolymers; polysaccharides; and mixtures of two or more of the foregoing polymers. The resultant coated glucosamine phosphate composition will be stable at ambient temperatures and upon exposure to the atmosphere.Type: GrantFiled: September 9, 2005Date of Patent: June 17, 2008Assignee: JFCT Technologies, LLCInventors: Sham N. Redkar, Vilas M. Chopdekar
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Patent number: 7001886Abstract: The invention pertains to a method for preparing diphenhydramine tannate by reacting diphenhydramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The diphenhydramine free base may be obtained by reacting a commercially available diphenhydramine salt such as diphenhydramine maleate with a base such as aqueous sodium hydroxide. The resultant diphenhydramine tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.Type: GrantFiled: April 16, 2004Date of Patent: February 21, 2006Assignee: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Raja G. Achari, James R. Schleck, Vilas M. Chopdekar
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Patent number: 6939856Abstract: The invention pertains to a method for preparing dexchlorpheniramine (“dexchlor”) tannate by reacting dexchlorpheniramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The dexchlorpheniramine free base may be obtained by reacting a commercially available dexchlorpheniramine salt such as dexchlorpheniramine maleate with a base such as aqueous sodium hydroxide. The resultant dexchlor tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.Type: GrantFiled: August 14, 2003Date of Patent: September 6, 2005Assignee: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Raja G. Achari, Angelo R. Mellozzi, Vilas M. Chopdekar
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Patent number: 6881744Abstract: The invention pertains to carbinoxamine tannate and to a method for preparing carbinoxamine tannate by reacting carbinoxamine free base at a temperature of about 50 to about 150° C. with tannic acid neat or as an aqueous slurry containing about 5 to about 30 wt. % water.Type: GrantFiled: December 20, 2002Date of Patent: April 19, 2005Assignee: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Dina Donatiello, Timothy N. Truong, Vilas M. Chopdekar
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Patent number: 6833360Abstract: The invention pertains to a method for preparing pseudoephedrine tannate by reacting pseudoephedrine free base at a temperature of about 70 to about 110° C. with tannic acid neat or as an aqueous slurry containing about 5 to about 30 wt. % water.Type: GrantFiled: December 20, 2002Date of Patent: December 21, 2004Assignee: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, James R. Schleck, Vilas M. Chopdekar
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Publication number: 20040198667Abstract: The invention pertains to a method for preparing diphenhydramine tannate by reacting diphenhydramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The diphenhydramine free base may be obtained by reacting a commercially available diphenhydranine salt such as diphenhydramine maleate with a base such as aqueous sodium hydroxide. The resultant diphenhydramine tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.Type: ApplicationFiled: April 16, 2004Publication date: October 7, 2004Applicant: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Raja G. Achari, James R. Schleck, Vilas M. Chopdekar
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Publication number: 20040157784Abstract: A composition comprising the tannate of an opioid. Suitable opioids include alfentanil, buprenorphine, butorphanol, carfentanil, cocaine, codeine, dezocine, diacetylmorphine, dihydrocodeine, dihydromorphine, diphenoxylate, diprenorphine, etorphine, fentanyl, heroin, hydrocodone, hydromorphone, &bgr;-hydroxy-3-methylfentanyl, levo-&agr;-acetylmethadol, levorphanol, lofentanil, meperidine, methadone, morphine, nalbuphine, nalmefene, o-methylnaltrexone, naloxone, naltrexone, oxycodone, oxymorphone, pentazocine, pethidine, propoxyphene, remifentanil, sufentanil, tilidine and tramadol. The opioid tannate may be readily prepared by reacting an opioid free base with tannic acid, either neat or in the presence of up to about 30 wt. % water, at a temperature of about 60 to about 150° C. and thereafter recovering the resultant opioid tannate. The opioid tannate may also be prepared by an alternative process that involves reacting the opioid free base with water at a temperature such that not more than about 10 wt.Type: ApplicationFiled: December 12, 2003Publication date: August 12, 2004Applicant: Jame Fine Chemicals, Inc.Inventors: Vilas M. Chopdekar, Sham N. Redkar, James R. Schlek
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Publication number: 20040033966Abstract: The invention pertains to a method for preparing dexchlorpheniramine (“dexchlor”) tannate by reacting dexchlorpheniramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The dexchlorpheniramine free base may be obtained by reacting a commercially available dexchlorpheniramine salt such as dexchlorpheniramine maleate with a base such as aqueous sodium hydroxide. The resultant dexchlor tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.Type: ApplicationFiled: August 14, 2003Publication date: February 19, 2004Applicant: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Raja G. Achari, Angelo R. Mellozzi, Vilas M. Chopdekar
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Publication number: 20030114535Abstract: The invention pertains to a novel composition comprising dextrochlorpheniramine tannate and to a method for preparing such tannate by reacting dextrochlorpheniramine free base at a temperature of about 60 to about 150° C. with tannic acid preferably neat or as an aqueous slurry containing about 5 to about 30 wt. % water. The dextrochlorpheniramine tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.Type: ApplicationFiled: July 27, 2002Publication date: June 19, 2003Applicant: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Raja G. Achari, Angelo R. Mellozzi, Vilas M. Chopdekar
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Publication number: 20030114392Abstract: The invention pertains to a method for preparing pseudoephedrine tannate by reacting pseudoephedrine free base at a temperature of about 70 to about 110° C. with tannic acid neat or as an aqueous slurry containing about 5 to about 30 wt. % water.Type: ApplicationFiled: December 20, 2002Publication date: June 19, 2003Applicant: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, James R. Schleck, Vilas M. Chopdekar
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Publication number: 20030114391Abstract: The invention pertains to carbinoxamine tannate and to a method for preparing carbinoxamine tannate by reacting carbinoxamine free base at a temperature of about 50 to about 150° C. with tannic acid neat or as an aqueous slurry containing about 5 to about 30 wt. % water.Type: ApplicationFiled: December 20, 2002Publication date: June 19, 2003Applicant: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Dina Donatiello, Timothy N. Truong, Vilas M. Chopdekar