Patents by Inventor Shan-Rong Shi

Shan-Rong Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quantifiable internal reference standards for immunohistochemistry and uses thereof
    Patent number: 8785150
    Abstract: Methods for identifying Quantifiable Internal Reference Standards (QIRS) for immunohistochemistry (IHC). Also disclosed are methods for using QIRS to quantify test antigens in IHC.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: July 22, 2014
    Assignee: University of Southern California
    Inventors: Clive R. Taylor, Shan Rong Shi
  • Quantifiable Internal Reference Standards For Immunohistochemistry And Uses Thereof
    Publication number: 20110306064
    Abstract: Methods for identifying Quantifiable Internal Reference Standards (QIRS) for immunohistochemistry (IHC). Also disclosed are methods for using QIRS to quantify test antigens in IHC.
    Type: Application
    Filed: June 30, 2011
    Publication date: December 15, 2011
    Inventors: Clive R. Taylor, Shan Rong Shi
  • Enhancement of immunochemical staining in aldehyde-fixed tissues
    Patent number: 5578452
    Abstract: A method for restoring immunoreactivity of a tissue, particularly decalcified tissue, fixed width an aldehyde fixative agent and embedded in an embedding medium, usually comprising celloidin, the method comprising the steps of contacting the tissue with an aldehyde releasing reagent solution comprising a solvent and an aldehyde releasing reagent and removing aldehyde released by the aldehyde releasing reagent from contact with the tissue by reacting the aldehyde in a substantially irreversible manner to form a non-aldehyde derivative, and removing excess base from the tissue. A preferred solution for celloidin-embedded decalcified tissue comprises methanolic sodium hydroxide at about one-third saturation.
    Type: Grant
    Filed: April 7, 1994
    Date of Patent: November 26, 1996
    Assignee: Biogenex Laboratories
    Inventors: Shan-Rong Shi, Atul K. Tandon, Krishan L. Kalra, Nagesh Malhotra, Sheng-Hui Su, Cheng-Zhi Yu
  • Antigen retrieval in formalin-fixed tissues using microwave energy
    Patent number: 5244787
    Abstract: A method of immunologically staining a formalin-fixed tissue preparation, which comprises (a) subjecting a formalin-fixed tissue preparation to microwave energy while the tissue preparation is submersed in water for a time sufficient to increase immunostaining efficiency; (b) removing the tissue preparation from the water and cooling; and (c) contacting the tissue preparation with an immunological staining reagent.
    Type: Grant
    Filed: January 31, 1991
    Date of Patent: September 14, 1993
    Assignee: Biogenex Laboratories
    Inventors: Marc E. Key, Shan-Rong Shi, Krishan L. Kalra
  • Enhancement of immunochemical staining in aldehyde-fixed tissue
    Patent number: RE40835
    Abstract: A method for restoring immunoreactivity of a tissue, particularly decalcified tissue, fixed width an aldehyde fixative agent and embedded in an embedding medium, usually comprising celloidin, the method comprising the steps of contacting the tissue with an aldehyde releasing reagent solution comprising a solvent and an aldehyde releasing reagent and removing aldehyde released by the aldehyde releasing reagent from contact with the tissue by reacting the aldehyde in a substantially irreversible manner to form a non-aldehyde derivative, and removing excess base from the tissue. A preferred solution for celloidin-embedded decalcified tissue comprises methanolic sodium hydroxide at about one-third saturation.
    Type: Grant
    Filed: August 12, 1993
    Date of Patent: July 7, 2009
    Assignee: BioGenx Laboratories, Inc.
    Inventors: Shan-Rong Shi, Atul K. Tandon, Krishan L. Kalra, Nagesh Malhotra, Sheng-Hui Su, Cheng-Zhi Yu