Abstract: A mouth operated input system that includes a controller and a mouth operated input device that is operably coupled to at least one device so as to provide input control thereof. The mouth operated input device includes a joystick module and an activation module operably coupled thereto. The activation module includes an activation module control board and further has mounted thereto a first actuator and a second actuator. The first actuator is mounted to be engaged by a user's mouth. The second actuator is mounted to the housing of the activation module and is configured as an optical switch. The activation module is movable in all directions so as to provide movement of the joystick operably coupled thereto. The controller of the present invention includes a database that stores input data from the joystick module and the first and second actuators. Multiple modes of operation are provided by the controller.