Patents by Inventor Shannon J. Turley

Shannon J. Turley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF CELL SURFACE PROTEIN INTERACTIONS AND METHODS AND COMPOSITIONS RELATED TO SAME
    Publication number: 20220119490
    Abstract: Provided herein are methods for identifying modulators of cell surface protein interactions and activities, as well as modulators of cell surface protein interactions and activities.
    Type: Application
    Filed: September 29, 2021
    Publication date: April 21, 2022
    Inventors: Nadia MARTINEZ-MARTIN, Shannon J. TURLEY, Erik VERSCHUEREN
  • ISOLATION AND USE OF HUMAN LYMPHOID ORGAN-DERIVED SUPPRESSIVE STROMAL CELLS
    Publication number: 20200061118
    Abstract: A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided.
    Type: Application
    Filed: August 12, 2019
    Publication date: February 27, 2020
    Applicants: The General Hospital Corporation d/b/a Massachusettes General Hospital, Dana-Farber Cancer Institute, Inc.
    Inventors: Anne Fletcher, Shannon J. Turley, Biju Parekkadan
  • Isolation and use of human lymphoid organ-derived suppressive stromal cells
    Patent number: 10420801
    Abstract: A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 24, 2019
    Assignees: The General Hospital Corporation, Dana-Farber Cancer Institute, Inc.
    Inventors: Anne Fletcher, Shannon J. Turley, Biju Parekkadan
  • ISOLATION AND USE OF HUMAN LYMPHOID ORGAN-DERIVED SUPPRESSIVE STROMAL CELLS
    Publication number: 20150050298
    Abstract: A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided.
    Type: Application
    Filed: March 13, 2013
    Publication date: February 19, 2015
    Inventors: Anne Fletcher, Shannon J. Turley, Biju Parekkadan
  • METHODS AND COMPOSITIONS FOR MODULATING IMMUNOLOGICAL TOLERANCE
    Publication number: 20110150845
    Abstract: The invention provides compositions and methods for modulating immune responses using mesenchymal stem cells. The invention further provides methods for inducing tolerance to self antigens using mesenchymal stem cells.
    Type: Application
    Filed: May 1, 2009
    Publication date: June 23, 2011
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Biju Parekkadan, Martin Leon Yarmush, Shannon J. Turley