Abstract: A dust removal system for a laser cleaning machine, including: a filter, a gas pump, a gas pipe and a dustproof nozzle. The dustproof nozzle is fixed on a laser cleaning head provided with a laser cleaning head gas inlet and a laser cleaning head gas outlet; one end of the gas pump is connected to the filter, and the other end thereof is connected to the laser cleaning head gas inlet through the gas pipe; a dustproof nozzle gas inlet is provided on both sides of the dustproof nozzle, a dustproof nozzle gas outlet is provided on the front end of the dustproof nozzle; and the laser cleaning head gas outlet is connected to the dustproof nozzle gas inlet through a pipeline assembly. The present disclosure has the advantages of keeping a lens clean, prolonging service life of the lens, reducing time for replacing the lens, and reducing costs.