Patents by Inventor Sharanabasappa Patil

Sharanabasappa Patil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spiro-fused cyclic ureas as inhibitors of rock
    Patent number: 10787450
    Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: September 29, 2020
    Assignee: Bristol-Myers Squibb Company
    Inventors: Rajeev S. Bhide, Mandar Shrikrishna Bodas, Pravin Sudhakar Shirude, Sharanabasappa Patil, Tarun Kumar Maishal, Kamalraj Thiyagarajan, Kumaresan Chinnakotti, Peter W. Glunz
  • SPIRO-FUSED CYCLIC UREAS AS INHIBITORS OF ROCK
    Publication number: 20190300528
    Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
    Type: Application
    Filed: July 6, 2017
    Publication date: October 3, 2019
    Inventors: Rajeev S. Bhide, Mandar Shrikrishna Bodas, Pravin Sudhakar Shirude, Sharanabasappa Patil, Tarun Kumar Maishal, Kamalraj Thiyagarajan, Kumaresan Chinnakotti, Peter W. Glunz
  • Cyclic ureas as inhibitors of rock
    Patent number: 10123993
    Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: November 13, 2018
    Assignee: Bristol-Myers Squibb Company
    Inventors: Peter W. Glunz, Doree F. Sitkoff, Navnath Dnyanoba Yadav, Mandar Shrikrishna Bodas, Rajeev S. Bhide, Sharanabasappa Patil, Kumaresan Chinnakotti, Prasanna Savanor Maddu Rao, Jeevan Prakash Shetty
  • Lactams as inhibitors of rock
    Patent number: 10112929
    Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: October 30, 2018
    Assignee: Bristol-Myers Squibb Company
    Inventors: Peter W. Glunz, Doree F. Sitkoff, Mandar Shrikrishna Bodas, Navnath Dnyanoba Yadav, Sharanabasappa Patil, Prasanna Savanor Maddu Rao
  • Tricyclic pyrido-carboxamide derivatives as rock inhibitors
    Patent number: 9914740
    Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: March 13, 2018
    Assignee: Bristol-Myers Squibb Company
    Inventors: Mimi L. Quan, Zilun Hu, Cailan Wang, Sharanabasappa Patil
  • LACTAMS AS INHIBITORS OF ROCK
    Publication number: 20180044326
    Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
    Type: Application
    Filed: March 8, 2016
    Publication date: February 15, 2018
    Applicant: Bristol-Myers Squibb Comapany
    Inventors: Peter W. Glunz, Doree F. Sitkoff, Mandar Shrikrishna Bodas, Navnath Dnyanoba Yadav, Sharanabasappa Patil, Prasanna Savanor Maddu Rao
  • CYCLIC UREAS AS INHIBITORS OF ROCK
    Publication number: 20180000788
    Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
    Type: Application
    Filed: January 8, 2016
    Publication date: January 4, 2018
    Inventors: Peter W. Glunz, Doree F. Sitkoff, Navnath Dnyanoba, Mandar Shrikrishna Bodas, Rajeev S. Bhide, Sharanabasappa Patil, Kumaresan Chinnakotti, Prasanna Savanor Maddu Rao
  • LXR modulators
    Patent number: 9834542
    Abstract: The present invention provides compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as modulators of liver X receptors (LXR), compositions comprising any of such novel compounds, methods of using these compounds or compositions as medicaments for prevention or treatment of diseases or disorders related to liver X receptor (LXR), as well as methods of preparing these LXR modulators and using them in the manufacture of medicaments.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 5, 2017
    Assignees: Bristo-Myers Squibb Company, Exelixis Patent Company LLC
    Inventors: Ellen K. Kick, Mandar Bodas, Raju Mohan, Meriah Valente, Nicholas Wurtz, Sharanabasappa Patil
  • LXR MODULATORS
    Publication number: 20160304499
    Abstract: The present invention provides compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as modulators of liver X receptors (LXR), compositions comprising any of such novel compounds, methods of using these compounds or compositions as medicaments for prevention or treatment of diseases or disorders related to liver X receptor (LXR), as well as methods of preparing these LXR modulators and using them in the manufacture of medicaments.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 20, 2016
    Applicants: BRISTOL-MYERS SQUIBB COMPANY, EXELIXIS PATENT COMPANY LLC
    Inventors: Ellen K. Kick, Mandar Bodas, Raju Mohan, Meriah Valente, Nicholas Wurtz, Sharanabasappa Patil
  • TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS
    Publication number: 20160152628
    Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
    Type: Application
    Filed: July 1, 2014
    Publication date: June 2, 2016
    Inventors: Mimi L. Quan, Zilun Hu, Cailan Wang, Sharanabasappa Patil