Patents by Inventor Sharee Otten

Sharee Otten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing doxorubicin
    Patent number: 5955319
    Abstract: The present invention concerns a process for improving doxorubicin production by means of a recombinant Streptomyces peucetius strain bearing a mutation in the gene dnrU coding for a protein involved in the metabolism of daunorubicin.
    Type: Grant
    Filed: July 28, 1997
    Date of Patent: September 21, 1999
    Assignee: Pharmacia & Upjohn, S.p.A.
    Inventors: Silvia Filippini, Umberto Breme, Anna Luisa Colombo, Natasha Lomovskaya, Leonid Fonstein, Sharee Otten, Charles R. Hutchinson
  • Daunorubin 14-hydroxylase
    Patent number: 5786190
    Abstract: The ability to convert daunorubicin to doxorubicin can be conferred on a host cell by transformation with a recombinant vector comprising DNA encoding daunorubicin 14-hydroxylase. The host cell can then be used to produce doxorubicin.
    Type: Grant
    Filed: December 3, 1996
    Date of Patent: July 28, 1998
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Augusto Solari Inventi, Umberto Breme, Anna Luisa Colombo, Charles Richard Hutchinson, Sharee Otten, Claudio Scotti
  • DNA encoding daunorubicin 14-hyroxylase and method for preparing doxorubicin
    Patent number: 5695966
    Abstract: The ability to convert daunorubicin to doxorubicin can be conferred on a host cell by transformation with a recombinant vector comprising DNA encoding daunorubicin 14-hydroxylase. The host cell can then be used to produce doxorubicin.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: December 9, 1997
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Augusto Solari Inventi, Umberto Breme, Anna Luisa Colombo, Charles Richard Hutchinson, Sharee Otten, Claudio Scotti