Patents by Inventor Shelby K. Doyle

Shelby K. Doyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecule modulators of the androgen receptor
    Patent number: 10961216
    Abstract: Provided herein are compounds useful for modulating the activity of an androgen receptor, or a variant thereof, and related compositions and methods. Compounds of the invention are useful for antagonizing the androgen receptor splice variant AR-v7, and for the treatment of castration-resistant prostate cancer.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: March 30, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: David Freeman, Nicholas B. Struntz, Shelby K. Doyle, Andre Richters, Angela N. Koehler
  • SMALL MOLECULE MODULATORS OF THE ANDROGEN RECEPTOR
    Publication number: 20190202800
    Abstract: Provided herein are compounds useful for modulating the activity of an androgen receptor, or a variant thereof, and related compositions and methods. Compounds of the invention are useful for antagonizing the androgen receptor splice variant AR-v7, and for the treatment of castration-resistant prostate cancer.
    Type: Application
    Filed: November 21, 2018
    Publication date: July 4, 2019
    Inventors: David Freeman, Nicholas B. Struntz, Shelby K. Doyle, Andre Richters, Angela N. Koehler