Patents by Inventor Sheng-Wan Tsao

Sheng-Wan Tsao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilization of aminosteroids for topical ophthalmic and other applications
    Patent number: 5538721
    Abstract: The invention provides methods for stabilizing amino-substituted steroid therapeutic agents in topical ophthalmic and other pharmaceutical formulations using effective stabilizing amounts of lightly cross-linked carboxy-containing polymers; and methods for stabilizing and solubilizing amino-substituted steroid therapeutic agents in such pharmaceutical formulations using effective stabilizing amounts of lightly cross-linked carboxy-containing polymers and amounts of selected cyclodextrin derivatives sufficient to at least partially solubilize the therapeutic agents. The cyclodextrin derivatives are selected from the group consisting of the hydroxypropyl, hydroxyethyl, glucosyl, maltosyl and maltotriosyl derivatives of .beta.- and .gamma.-cyclodextrin. Stabilized and stabilized/solubilized pharmaceutical compositions adapted for various routes of administration are also described.
    Type: Grant
    Filed: February 28, 1994
    Date of Patent: July 23, 1996
    Assignee: InSite Vision Incorporated
    Inventors: John C. Babcock, Jon R. Polansky, Lyle M. Bowman, Sheng-Wan Tsao, Erwin C. C. Si, Santosh K. Chandrasekaran
  • Stabilization of aminosteroids for topical ophthalmic and other applications
    Patent number: 5332582
    Abstract: The invention provides methods for stabilizing amino-substituted steroid therapeutic agents in topical ophthalmic and other pharmaceutical formulations using effective stabilizing amounts of lightly cross-linked carboxy-containing polymers; Stabilized and stabilized/solubilized pharmaceutical compositions adapted for various routes of administration are also described.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: July 26, 1994
    Assignee: Insite Vision Incorporated
    Inventors: John C. Babcock, Jon R. Polansky, Lyle M. Bowman, Sheng-Wan Tsao, Erwin C. Si, Santosh K. Chandrasekaran
  • Aminosteroids for ophthalmic use
    Patent number: 5256408
    Abstract: Methods and compositions for preventing or treating ophthalmic diseases or disorders wherein an ophthalmically effective amount of the C.sub.20 through C.sub.26 aminosteroids of formula XI and their pharmaceutical, acceptable salts, hydrates or solvates is administered in an inert vehicle to arrest oxidation processes damaging to the eye.
    Type: Grant
    Filed: February 19, 1992
    Date of Patent: October 26, 1993
    Assignee: Insite Vision Incorporated
    Inventors: John G. Babcock, Jon R. Polansky, Lyle M. Bowman, Sheng-Wan Tsao, Erwin C. Si, Santosh K. Chandrasekaran
  • Aminosteroids for ophthalmic use
    Patent number: 5252319
    Abstract: Methods and compositions for preventing or treating ophthalmic diseases or disorders wherein an ophthalmically effective amount of the C.sub.20 through C.sub.26 aminosteroids of formula XI and their pharmaceutical, acceptable salts, hydrates or solvates is administered in an inert vehicle to arrest oxidation processes damaging to the eye.
    Type: Grant
    Filed: February 19, 1992
    Date of Patent: October 12, 1993
    Assignee: Insite Vision Incorporated
    Inventors: John C. Babcock, Jon R. Polansky, Lyle M. Bowman, Sheng-Wan Tsao, Erwin C.-C. Si, Santosh K. Chandrasekaran
  • Aminosteroids for ophthalmic use
    Patent number: 5209926
    Abstract: Methods and compositions for preventing or treating ophthalmic diseases or disorders wherein an ophthalmically effective amount of the C.sub.20 through C.sub.26 aminosteroids of formula XI and their pharmaceutical, acceptable salts, hydrates or solvates is administered in an inert vehicle to arrest oxidation processes damaging to the eye.
    Type: Grant
    Filed: August 24, 1992
    Date of Patent: May 11, 1993
    Assignee: InSite Vision Incorporated
    Inventors: John C. Babcock, Jon R. Polansky, Lyle M. Bowman, Sheng-Wan Tsao, Erwin C. Si, Santosh K. Chandrasekaran
  • Aminosteroids for ophthalmic use
    Patent number: 5124154
    Abstract: Methods and compositions for preventing or treating ophthalmic diseases or disorders wherein an ophthalmically effective amount of the C.sub.20 through C.sub.26 aminosteroids of formula XI and their pharmaceutical, acceptable salts, hydrates or solvates is administered in an inert vehicle to arrest oxidation processes damaging to the eye.
    Type: Grant
    Filed: June 12, 1990
    Date of Patent: June 23, 1992
    Assignee: InSite Vision Incorporated
    Inventors: John C. Babcock, Jon R. Polansky, Lyle M. Bowman, Sheng-Wan Tsao, Erwin C. Si, Santosh K. Chandrasekran