Patents by Inventor Sheryl L. Meyer

Sheryl L. Meyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for detecting cell apoptosis
    Patent number: 7256252
    Abstract: Methods for the biochemical and immunohistochemical detection of cell apoptosis are described. The methods utilize the detection and measurement of polypeptide fragments generated during apoptosis. Conditions associated with apoptosis may be detected by the methods of this invention. Methods are also presented for the screening of potential therapeutic compounds which inhibit or stimulate apoptosis. Kits for detection of apoptosis and diagnosis of diseases are also provided.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: August 14, 2007
    Assignee: Cephalon, Inc.
    Inventors: Robert Siman, Donna Bozyczko-Coyne, Sheryl L. Meyer
  • Novel mixed lineage kinase (7) (mlk7) polypeptide polynucleotides encoding the same and methods of use thereof
    Publication number: 20040185460
    Abstract: The present invention provides isolated mixed lineage kinase (7) (MLK) polynucleotides, expression vectors, host cells, isolated polypeptides, methods of producing polypeptides, isolated antibodies, compositions having the foregoing, methods for identifying a compound that binds a polypeptide or polynucleotide, and to methods for identifying a compound that modulates the activity of a poypeptide.
    Type: Application
    Filed: April 20, 2004
    Publication date: September 23, 2004
    Inventors: Thelma S Angeles, John T. Durkin, Beverly P Holskin, Sheryl L Meyer, Chrysanthe M Spais
  • Recombinant enzymatically active calpain expressed in a baculovirus system
    Patent number: 6057143
    Abstract: The present invention is directed to mammalian enzymatically active calpain produced in insect cells by recombinant means. Recombinant vectors and baculoviruses containing cDNA encoding the 80 kDa subunit, 30 kDa subunit, and both subunits are described. Methods for producing recombinant enzymatically active mammalian calpain are also described.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: May 2, 2000
    Assignee: Cephalon, Inc.
    Inventors: Sheryl L. Meyer, Richard W. Scott, Robert Siman
  • Methods for detecting cell apoptosis
    Patent number: 6048703
    Abstract: Methods for the biochemical and immunohistochemical detection of cell apoptosis are described. The methods utilize the detection and measurement of polypeptide fragments generated during apoptosis. Conditions associated with apoptosis may be detected by the methods of this invention. Methods are also presented for the screening of potential therapeutic compounds which inhibit or stimulate apoptosis. Kits for detection of apoptosis and diagnosis of diseases are also provided.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: April 11, 2000
    Assignee: Cephalon, Inc.
    Inventors: Robert Siman, Donna Bozyczko-Coyne, Sheryl L. Meyer, Ratan Venkatraman Bhat
  • Recombinant enzymatically active calpain expressed in a baculovirus system
    Patent number: 5869336
    Abstract: The present invention is directed to mammalian enzymatically active calpain produced in insect cells by recombinant means. Recombinant vectors and baculoviruses containing cDNA encoding the 80 kDa subunit, 30 kDa subunit, and both subunits are described. Methods for producing recombinant enzymatically active mammalian calpain are also described.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: February 9, 1999
    Assignee: Cephalon, Inc.
    Inventors: Sheryl L. Meyer, Richard W. Scott, Robert Siman