Patents by Inventor Shiao-Chun Tu

Shiao-Chun Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequence determination using multiply tagged polymerizing agents
    Publication number: 20070292867
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: December 20, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Tagged monomers for use in sequence determination
    Publication number: 20070275395
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: November 29, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Sequence determination by direct detection
    Publication number: 20070184475
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: August 9, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Data stream determination
    Publication number: 20070172862
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Methods for sequence determination
    Publication number: 20070172867
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Methods for sequence determination using depolymerizing agent
    Publication number: 20070172866
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Enzymatic nucleic acid synthesis: compositions and methods
    Publication number: 20070172860
    Abstract: Nucleotide triphosphate probes containing a molecular and/or atomic tag on a a ? and/or ? phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Sequence determination in confined regions
    Publication number: 20070172865
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Enzymatic nucleic acid synthesis: methods for inhibiting pyrophosphorolysis during sequencing synthesis
    Publication number: 20070172869
    Abstract: Nucleotide triphosphate probes containing a molecular and/or atomic tag on a ? and/or ? phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Composition for sequence determination
    Publication number: 20070172864
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Enzymatic nucleic acid synthesis: methods for direct detection of tagged monomers
    Publication number: 20070172859
    Abstract: Nucleotide triphosphate probes containing a molecular and/or atomic tag on a a ? and/or ? phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Compositions for sequence determination using tagged polymerizing agents and tagged monomers
    Publication number: 20070172868
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Mutant polymerases
    Publication number: 20070172861
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Enzymatic nucleic acid synthesis: compositions including pyrophosphorolysis inhibitors
    Publication number: 20070172819
    Abstract: Nucleotide triphosphate probes containing a molecular and/or atomic tag on a ? and/or ? phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Compositions and methods for sequence determination
    Publication number: 20070172863
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Methods for sequence determination
    Publication number: 20070172858
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 26, 2007
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
    Patent number: 7211414
    Abstract: Nucleotide triphosphate probes containing a molecular and/or atomic tag on a a ? and/or ? phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: May 1, 2007
    Assignee: Visigen Biotechnologies, Inc.
    Inventors: Susan H. Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Real-time sequence determination
    Publication number: 20050266424
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 8, 2004
    Publication date: December 1, 2005
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Methods for real-time single molecule sequence determination
    Publication number: 20050260614
    Abstract: A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
    Type: Application
    Filed: December 8, 2004
    Publication date: November 24, 2005
    Inventors: Susan Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu
  • Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
    Publication number: 20030134807
    Abstract: Nucleotide triphosphate probes containing a molecular and/or atomic tag on a a &ggr; and/or &bgr; phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
    Type: Application
    Filed: December 3, 2001
    Publication date: July 17, 2003
    Inventors: Susan H. Hardin, Xiaolian Gao, James Briggs, Richard Willson, Shiao-Chun Tu