Patents by Inventor Shigehito OSAWA

Shigehito OSAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition controlling pharmacokinetics in the body
    Patent number: 11957708
    Abstract: The present invention provides a composition that controls pharmacokinetics. Specifically, the present invention provides: a composition for controlling pharmacokinetics, the composition containing a polyvalent cation as an active ingredient; and a method for controlling pharmacokinetics using the polyvalent cation.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: April 16, 2024
    Assignee: KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION
    Inventors: Kazunori Kataoka, Shigehito Osawa, Satoshi Uchida, Kotaro Hayashi, Anjaneyulu Dirisala, Kazuko Toh
  • OCULAR-TENSION-INCREASING AGENT CAPABLE OF BEING DEPRIVED OF DRUG ACTIVITY BY TEMPERATURE CONTROL
    Publication number: 20230398140
    Abstract: The disclosure provides an ocular tension increasing agent containing a temperature responsive polymer. Ocular tension can be increased by administering an ocular tension increasing agent according to the present invention to a predetermined region of an eye and ocular tension can be controlled, if necessary, by temperature.
    Type: Application
    Filed: October 28, 2021
    Publication date: December 14, 2023
    Applicant: UNIVERSITY OF YAMANASHI
    Inventors: Yuji TANAKA, Kenji KASHIWAGI, Shigehito OSAWA
  • TEMPERATURE-RESPONSIVE DRUG/POLYMER COMPOUND AND APPLICATION OF COMPOUND TO DRUG DELIVERY
    Publication number: 20220331439
    Abstract: A drug-polymer conjugate having thermoresponsiveness includes at least one drug conjugated to at least one end portion of at least one thermoresponsive polymer segment having a lower critical solution temperature. The drug-polymer conjugate is capable of forming a micellular aggregate in an aqueous medium at temperatures equal to or above the lower critical solution temperature. The drug-polymer conjugate or the micellular aggregate thereof may be administered to and absorbed in the lungs.
    Type: Application
    Filed: July 27, 2020
    Publication date: October 20, 2022
    Inventors: Kanjiro MIYATA, Beob Soo KIM, Shigehito OSAWA, Mitsuru NAITO, Hiroyuki CHAYA
  • COMPOSITION CONTROLLING PHARMACOKINETICS IN THE BODY
    Publication number: 20210038634
    Abstract: The present invention provides a composition that controls pharmacokinetics. Specifically, the present invention provides: a composition for controlling pharmacokinetics, the composition containing a polyvalent cation as an active ingredient; and a method for controlling pharmacokinetics using the polyvalent cation.
    Type: Application
    Filed: March 12, 2019
    Publication date: February 11, 2021
    Applicant: KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION
    Inventors: Kazunori KATAOKA, Shigehito OSAWA, Satoshi UCHIDA, Kotaro HAYASHI, Anjaneyulu DIRISALA, Kazuko TOH
  • Micelle composition for nucleic acid delivery using temperature-sensitive polymer and method for producing same
    Patent number: 10668169
    Abstract: Provided are a micelle composition for nucleic acid delivery using a temperature-sensitive polymer, and a method for producing the micelle. For example, provided is a polyion complex comprising a temperature-sensitive copolymer and a nucleic acid, wherein the temperature-sensitive copolymer comprises a cationic block and a temperature-sensitive block, the cationic block optionally carrying a hydrophilic block linked thereto, and the polyion complex is obtained by mixing the temperature-sensitive copolymer with the nucleic acid under temperature conditions equal to or lower than the lower critical solution temperature (LCST) of the temperature-sensitive copolymer.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: June 2, 2020
    Assignee: The University of Tokyo
    Inventors: Kazunori Kataoka, Yasutaka Anraku, Kanjiro Miyata, Meng Zheng, Shigehito Osawa
  • MICELLE COMPOSITION FOR NUCLEIC ACID DELIVERY USING TEMPERATURE-SENSITIVE POLYMER AND METHOD FOR PRODUCING SAME
    Publication number: 20180289835
    Abstract: Provided are a micelle composition for nucleic acid delivery using a temperature-sensitive polymer, and a method for producing the micelle. For example, provided is a polyion complex comprising a temperature-sensitive copolymer and a nucleic acid, wherein the temperature-sensitive copolymer comprises a cationic block and a temperature-sensitive block, the cationic block optionally carrying a hydrophilic block linked thereto, and the polyion complex is obtained by mixing the temperature-sensitive copolymer with the nucleic acid under temperature conditions equal to or lower than the lower critical solution temperature (LCST) of the temperature-sensitive copolymer.
    Type: Application
    Filed: May 20, 2016
    Publication date: October 11, 2018
    Inventors: Kazunori KATAOKA, Yasutaka ANRAKU, Kanjiro MIYATA, Meng ZHENG, Shigehito OSAWA