Patents by Inventor Shigemi Aoyama

Shigemi Aoyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant Avipox virus encoding polypeptide of mycoplasma gallisepticum, and utilized a live vaccine
    Patent number: 5871742
    Abstract: A polypeptide exhibiting the antigenicity of Mycoplasma gallisepticum, a fused polypeptide comprising the above polypeptide and, connected to the N-terminus thereof, a signal membrane anchor of a type II outer-membrane polypeptide of a virus that infects birds, or a polypeptide capable of reacting with a mycoplasma-immune serum or a mycoplasma-infected serum and exhibiting a substantially pure antigenecity, respectively having amino acid sequences of about 32 kDa, about 40 kDa, or about 70 kDa. The expression with a recombinant virus of a polypeptide modified to such an extent as to exhibit an antigenicity equivalent to that of any of the above polypeptides. The use of a recombinant virus as a live vaccine.
    Type: Grant
    Filed: September 25, 1995
    Date of Patent: February 16, 1999
    Assignees: Nippon Zeon Co., Ltd, Shionogi & Co., Ltd.
    Inventors: Shuji Saitoh, Setsuko Ohkawa, Sakiko Saeki, Ikuroh Ohsawa, Hirono Funato, Yoshikazu Iritani, Shigemi Aoyama, Kiyohito Takahashi
  • Poultry mycoplasma antigens and recombinant vectors containing the gene as well as diagnostics and vaccines utilizing the same
    Patent number: 5766594
    Abstract: Antigen proteins of Mycoplasma gallisepticum, genes encoding the antigen protein, recombinant vectors integrated with the gene and hosts transformed with the vector are provided. Diagnostics and vaccine using the antigen protein produced by such hosts are effective for poultry, especially chicken infected with Mycoplasma gallisepticum. Vaccination can maintain poultry free of Mycoplasma gallisepticum infection.
    Type: Grant
    Filed: January 2, 1997
    Date of Patent: June 16, 1998
    Assignees: Nippon Zeon Co., Ltd., Shionogi & Co., Ltd.
    Inventors: Kazumi Kodama, Shuji Saito, Noboru Yanagida, Kouichi Kamogawa, Yoshikazu Iritani, Shigemi Aoyama
  • Poultry Mycoplasma antigens and recombinant vectors containing the gene as well as diagnostics and vaccines utilizing the same
    Patent number: 5621076
    Abstract: Antigen proteins of Mycoplasma gallisepticum, genes encoding the antigen protein, recombinant vectors integrated with the gene and hosts transformed with the vector are provided. Diagnostics and vaccine using the antigen protein produced by such hosts are effective for poultry, especially chicken infected with Mycoplasma gallisepticum. Vaccination can maintain poultry free of Mycoplasma gallisepticum infection.
    Type: Grant
    Filed: September 2, 1994
    Date of Patent: April 15, 1997
    Assignees: Nippon Zeon Co., Ltd., Shionogi & Co., Ltd.
    Inventors: Kazumi Kodama, Shuji Saito, Noboru Yanagida, Kouichi Kamogawa, Yoshikazu Iritani, Shigemi Aoyama
  • Poultry mycoplasma antigen, gene thereof and recombinant vectors containing the gene as well as vaccines utilizing the same
    Patent number: 5489430
    Abstract: A highly effective vaccine for Mycoplasma gallisepticum infection utilizing a substantially pure protein capable of reacting with Mycoplasma gallisepticum immunized serum or Mycoplasma gallisepticum infected serum, having a molecular weight of about 40 kilodaltons encoded by DNA sequence derived from Mycoplasma gallisepticum and having a specific restriction enzyme map, or a protein functionally equivalent thereto.
    Type: Grant
    Filed: January 25, 1994
    Date of Patent: February 6, 1996
    Assignees: Nippon Zeon Co., Ltd., Shionogi & Co., Ltd.
    Inventors: Shuji Saito, Setsuko Ohkawa, Ayumi Fujisawa, Yoshikazu Iritani, Shigemi Aoyama