Abstract: A method for producing a biodegradable polyoxyalkylene derivative, includes: reacting a biodegradable polyoxyalkylene compound represented by the formula (1) as defined herein with a compound represented by one of the formulae (I) to (IV) as defined herein in a presence of an alkaline solid salt, the biodegradable polyoxyalkylene derivative being represented by the formula (2) as defined herein.

Abstract: A novel A1-B-A2 polymer having a number average molecular weight of 10000 to 100000 is provided that has excellent bioabsorbability so as to disappear in a predetermined period of time even when embedded in a large amount in the body, has good kinetic properties, and is useful for preparing tissue anti-adhesion films. This polymer is composed of segments A1 and A2 each having at least either of modified and unmodified amino acid groups, and segment B composed of PEG having a number average molecular weight of 8000 to 50000. The polymer contains both the modified and unmodified amino acid groups, the content of the modified amino acids is 20 to 85 mol % of all the amino acids in the polymer, and segment A1 is bonded to one end of segment B and segment A2 is bonded to the other end of segment B.

Abstract: A method for producing a biodegradable polyoxyalkylene derivative, includes: reacting a biodegradable polyoxyalkylene compound represented by the formula (1) as defined herein with a compound represented by one of the formulae (I) to (IV) as defined herein in a presence of an alkaline solid salt, the biodegradable polyoxyalkylene derivative being represented by the formula (2) as defined herein.

Abstract: A novel A1-B-A2 polymer having a number average molecular weight of 10000 to 100000 is provided that has excellent bioabsorbability so as to disappear in a predetermined period of time even when embedded in a large amount in the body, has good kinetic properties, and is useful for preparing tissue anti-adhesion films. This polymer is composed of segments A1 and A2 each having at least either of modified and unmodified amino acid groups, and segment B composed of PEG having a number average molecular weight of 8000 to 50000. The polymer contains both the modified and unmodified amino acid groups, the content of the modified amino acids is 20 to 85 mol % of all the amino acids in the polymer, and segment A1 is bonded to one end of segment B and segment A2 is bonded to the other end of segment B.

Abstract: A process for producing a (meth)acrylate derivative including reacting a compound of formula (1) (wherein R.sup.1 is H or CH.sub.3 ; A is C.sub.1 -C.sub.10 alkylene; and p is 1 to 10) with a chloro-dioxaphosphorus compound of formula (2) (wherein q is 0 or 1) in the presence of a secondary amine of formula (3) (wherein R.sup.2 and R.sub.3 are each C.sub.3 -C.sub.8 alkyl, cycloalkyl, C.sub.6 -C.sub.9 aryl, arylalkyl, etc.) to produce a (meth)acrylate derivative of formula (4) and further reacting the same with a tertiary amine of formula (5) (wherein R.sup.4, R.sup.5 and R.sup.6 are each C.sub.1 -C.sub.4 alkyl etc.) to provide a (meth)acrylate derivative of formula (6).

Abstract: A reactive vesicle comprising, as a vesicle-forming component, a reactive phospholipid derivative represented by the following general formula (1) and a functional substance-fixed vesicle prepared by reacting the reactive vesicle with a functional substance: ##STR1## in which R.sup.1 C(.dbd.O) and R.sup.2 C(.dbd.O) each represent an aliphatic acyl group, R.sup.3 denotes hydrogen atom or methyl group, OA represents an oxyalkylene group of 2-4 carbon atoms, n indicates the average number of moles of added oxyalkylene group and is 1-1,000, p is 0 or 1, X represents ##STR2## with q and r each being an integer of 0 to 4 or 1 to 4, respectively, and M denotes hydrogen atom or an alkli metal atom.

Abstract: The present invention provides a polymer complex of a sugar response type having boronic acid groups in the polymer. Medicines may be contained or linked, preferably, the medicines have hydroxy groups. The polymer having boronic acid groups and the medicine having hydroxy groups may be linked by boronic acid ester bonds. The complex may also comprises polymers having boronic acid groups and polymers having hydroxy groups, and these polymers may be cross-linked.

Abstract: A novel and useful phospholipid derivative to be used for a reactive vesicle-forming agent, which is represented by the following general formula (1): ##STR1## in which R.sup.1 C(.dbd.O) and R.sup.2 C(.dbd.O) represent each an aliphatic acyl group, R.sup.3 denotes hydrogen atom or methyl group, OA represents an oxyalkylene group of 2-4 carbon atoms, n indicates the average addition mole number of added oxyalkylene group and is 1-1,000, p is 0 or 1, X represents ##STR2## with q and r being each an integer of 0 to 4 or 1 to 4, respectively, and M denotes hydrogen atom or an alkali metal atom.

Abstract: A card reader control system includes a measuring device which measures a time interval of a clock signal which is developed from a card reader when a card is manually driven to travel in the card reader. The card reader control system stores the maximum time interval and the minimum time interval of the clock signal measured by the measuring device. When either one or both of the maximum time interval and the minimum time interval is not included in a preferred range, an alarm buzzer is enabled to indicate that the card speed is not suited for the reading operation.

Abstract: A CRT display control system controls a character display operation on a CRT image screen. The entire character line height is divided into a display allowed raster section and a display inhibited raster section. The display allowed raster section is provided for displaying characters. The display inhibited raster section functions as a line spacing. When the character matrix size is changed, the display allowed raster section and the display inhibited raster section are modified through the use of a preset system so that the line spacing is easily determined without modifying the circuit construction.

Abstract: A data reader reads data from a magnetic tape using a reproduction head. This data is presented to a loading control circuit which amplifies the signal produced by the reproduction head, as needed. The sufficiency of the volume level produced by the loading control circuit is detected by a volume adjustment detection circuit which detects the sufficiency of the signal level. If the signal level is insufficient, a buzzer is sounded indicating to the operator of the data reader that the gain level of the loading control circuit is insufficient. If the gain level is determined to be sufficient by the volume adjustment detection circuit, a signal path to a data detection circuit is enabled. The data detection circuit determines the presence of actual data and presents this data to a readout circuit.

Abstract: An improved modulator is capable of facilitating recording and reproducing on and from an audio cassette tape digital signals such as programs and numerical data coming from digital signal processing apparatus including an electronic cash register as well as providing safety for the audio cassette tape when in operation. The modulator includes a control circuit for detecting and counting carrier signals and outputting desired information in response to a data transfer instruction and a state detector governed by the control circuit wherein the carrier signals are sent out via data transfer lines when the detector is in a specific state. The control circuit may be implemented with a microprocessor.

Abstract: A data recorder for recording data in the form of audio or digital signals into a cassette tape comprises a first circuit for recording check signals and a second circuit for recording true signals. The first circuit allows the check signals to be recorded in a first section of the cassette tape to check the amplitude of a sound volume in which the check signals are sounded. The second circuit enables the true signals to be recorded in a second section of the cassette tape under the condition that the amplitude of the sound volume of the check signals is adequately adjusted. A data reader for reading out the thus recorded data includes a first detection circuit for determining whether the read-out signals have a sufficient level for reading out purposes, an announcing device for announcing the need to adjust a sound volume, and a read-out circuit for reading out true data from the cassette tape.

Abstract: An electronic apparatus comprises a central processor unit (CPU) for controlling the operation of the electronic apparatus, and a dynamic random access memory (RAM). The CPU develops a refresh control signal for refreshing the memory data stored in the dynamic RAM. An additional refresh control circuit is provided outside of the CPU for developing another refresh control signal. The additional refresh control circuit is connected to receive the electric power from a backup battery included in the electronic apparatus. When the service interruption occurs, the additional refresh control circuit is enabled to maintain the memory data stored in the dynamic RAM.