Patents by Inventor Shikha MISHRA

Shikha MISHRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Delivery of target specific nucleases
    Patent number: 11690921
    Abstract: Described herein are lipid nanoparticles comprising cationic lipids and other lipids and also comprising engineered nucleases facilitate transfer of nucleic acids to cells.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: July 4, 2023
    Assignees: Sangamo Therapeutics, Inc., Life Technologies Corporation
    Inventors: Anthony Conway, Xavier de Mollerat du Jeu, Shikha Mishra
  • CATIONIC LIPID COMPOSITIONS FOR TISSUE-SPECIFIC DELIVERY
    Publication number: 20220001023
    Abstract: Provided herein are, inter alia, compositions and methods useful for the in vivo delivery of bioactive agents (e.g., therapeutic or diagnostic agents). The compositions provided herein include cationic lipids, helper lipids and a biostability enhancing agent, which together form a lipid aggregate with the bioactive agent and allow for the systemic delivery of the bioactive agent to, for example, lung tissue without the requirement for biomolecular targeting.
    Type: Application
    Filed: July 16, 2021
    Publication date: January 6, 2022
    Inventors: Shikha MISHRA, Xavier de MOLLERAT du JEU
  • DELIVERY OF TARGET SPECIFIC NUCLEASES
    Publication number: 20190365924
    Abstract: Described herein are lipid nanoparticles comprising cationic lipids and other lipids and also comprising engineered nucleases facilitate transfer of nucleic acids to cells.
    Type: Application
    Filed: May 15, 2019
    Publication date: December 5, 2019
    Inventors: Anthony Conway, Xavier de Mollerat du Jeu, Shikha Mishra
  • CATIONIC LIPID COMPOSITIONS FOR TISSUE-SPECIFIC DELIVERY
    Publication number: 20190060482
    Abstract: Provided herein are, inter alia, compositions and methods useful for the in vivo delivery of bioactive agents (e.g., therapeutic or diagnostic agents). The compositions provided herein include cationic lipids, helper lipids and a biostability enhancing agent, which together form a lipid aggregate with the bioactive agent and allow for the systemic delivery of the bioactive agent to, for example, lung tissue without the requirement for biomolecular targeting.
    Type: Application
    Filed: July 17, 2018
    Publication date: February 28, 2019
    Inventors: Shikha MISHRA, Xavier de MOLLERAT du JEU