Patents by Inventor Shinichiro Kato

Shinichiro Kato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120076798
    Abstract: Provided herein are antibodies that immunospecifically bind to an hLIGHT polypeptide; isolated nucleic acids encoding the antibodies; vectors and host cells comprising nucleic acids encoding the antibodies; methods of making the antibodies; and a method of treating a hLIGHT-mediated disease in a subject comprising administering to the subject the antibodies. In preferred embodiments, the anti-hLIGHT antibodies provided herein will ameliorate, neutralize or otherwise inhibit hLIGHT biological activity in vivo (e.g., the hLIGHT-mediated production or secretion of CCL20, IL-8 or RANTES from a cell expressing a hLIGHT receptor). Also provided herein is a method for the detection of hLIGHT in a sample as well as a method for ameliorating, neutralizing or otherwise inhibiting hLIGHT activity, e.g., in a human subject suffering from a disorder in which hLIGHT activity is detrimental.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 29, 2012
    Applicants: LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY, KYOWA HAKKO KIRIN CO., LIMITED
    Inventors: Steven W. Granger, Shinichiro Kato, Carl F. Ware
  • Patent number: 8138894
    Abstract: An in-vehicle device notifies a mobile device of a frequency channel which has been stored in its memory unit, and sets the notified channel to a reception channel. The mobile device transmits a reply signal through the channel notified from the in-vehicle device. When the in-vehicle device determines that a code included in the received reply signal is identical with a code specific to a vehicle, the in-vehicle device stores the channel used for receiving the reply signal in its memory unit. As a result, each communication is conducted through the same channel, which enabled the successful communication previously, thereby enhancing the certainty of communication.
    Type: Grant
    Filed: January 10, 2008
    Date of Patent: March 20, 2012
    Assignee: Denso Corporation
    Inventors: Shinichiro Kato, Masahiro Sugiura, Kazuhiro Nakashima
  • Patent number: 8124091
    Abstract: Human, humanized and chimeric monoclonal antibodies that bind to influenza M2 protein. A human monoclonal antibody that binds to influenza M2 protein having different amino acid sequences. The antibodies are useful for, among other things, treatment, diagnostics, purifying and isolating M2 or influenza virus, and identifying the presence of M2 or influenza virus in a sample or a subject.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: February 28, 2012
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Shinichiro Kato, Rongfang Wang
  • Patent number: 8058402
    Abstract: Provided herein are antibodies, such as fully human antibodies that immunospecifically bind to an hLIGHT polypeptide. Also provided are isolated nucleic acids encoding antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Further provided are vectors and host cells comprising nucleic acids encoding antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Also provided are methods of making antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Also provided herein is a method of treating a hLIGHT-mediated disease in a subject comprising administering to the subject an antibody, such as a fully human antibody, that immunospecifically binds to a hLIGHT polypeptide. In preferred embodiments, that anti-hLIGHT antibodies provided herein will ameliorate, neutralize or otherwise inhibit hLIGHT biological activity in vivo (e.g.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: November 15, 2011
    Assignees: Kyowa Hakko Kirin, La Jolla Institute for Allergy and Immunology
    Inventors: Steven W. Granger, Shinichiro Kato, Carl F. Ware
  • Publication number: 20110239786
    Abstract: An electric power steering apparatus includes a steering shaft for transmitting a steering force of a steering handlebar to a wheel and an upper bearing provided at a location upward from a vehicle body frame so as to rotatably support an upper part of the steering shaft. A lower bearing is provided at a location downward from the vehicle body frame, so as to rotatably support a lower part of the steering shaft. A torque sensor detects a torsional torque applied to the steering shaft. An electric motor imparts a steering force to the steering shaft based on the torsional torque detected by the torque sensor. The electric motor is mounted to the steering shaft between the upper bearing and the lower bearing, while the torque sensor is mounted to the steering shaft at place upward from the upper bearing.
    Type: Application
    Filed: March 28, 2011
    Publication date: October 6, 2011
    Inventors: Tsuyoshi TSUDA, Takeshi Wakabayashi, Shinichiro Kato, Hiroyuki Kaneta, katsumi Sahoda
  • Publication number: 20110239787
    Abstract: A bending load acting on a steering shaft only with a magnetostrictive torque sensor, without separately providing a sensor for detecting the bending moment. A storage unit stores, as an initial characteristic curve formed from initial detection values, a characteristic curve formed from detection values of each of a first detection coil and a second detection coil when only twisting torque is applied to a steering shaft. A bending load detector provided in an ECU detects a bending load amount acting on the steering shaft based on a difference between each detection value of the first and second detection coils and the initial detection value on the initial characteristic curve corresponding to the detection value.
    Type: Application
    Filed: March 28, 2011
    Publication date: October 6, 2011
    Inventors: Shinichiro Kato, Takeshi Wakabayashi, Katsumi Sahoda, Tsuyoshi Tsuda, Hiroyuki Kaneta
  • Patent number: 8003106
    Abstract: Human, humanized and chimeric monoclonal antibodies that bind to influenza M2 protein. The antibodies are useful for, among other things, treatment, diagnostics, purifying and isolating M2 or influenza virus, and identifying the presence of M2 or influenza virus in a sample or a subject.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: August 23, 2011
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Toshifumi Mikayama, Rongfang Wang, Shinichiro Kato
  • Publication number: 20110144312
    Abstract: The invention relates to IL-1O Receptor alpha (IL-1OR?) antibodies and subsequences thereof, human and humanized IL-10 Receptor alpha (IL-IOR?) antibodies and subsequences thereof, isolated and purified IL-10 Receptor alpha (IL-1OR?) antibodies and subsequences thereof, compositions including IL-10 Receptor alpha (IL-1OR?) antibodies and subsequences thereof, and methods that employ IL-10 Receptor alpha (IL-1OR?) antibodies and subsequences thereof. The invention includes among other things, methods of treating a pathogen infection, pathogen reactivation, and methods of vaccinating or immunizing against a pathogen infection, which include, for example, administering an IL-10 Receptor alpha (IL-1OR?) antibody or subsequence, to treat a pathogen infection, pathogen reactivation or for vaccination or immunization.
    Type: Application
    Filed: May 27, 2009
    Publication date: June 16, 2011
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Shinichiro Kato, Rachel Soloff Nugent, Tomoyuki Tahara, Paul Rogers, Aihua Song
  • Publication number: 20110132138
    Abstract: A nitrocarburized crankshaft member made of a steel that includes C in an amount by weight of 0.25 to 0.32% as a required element and an optional element that may be included, and Fe and inevitable impurities in a remaining portion. The steel-made crankshaft member mainly includes ferrite and perlite, wherein at least a portion of the steel surface thereof having a ferrite surface area of 50% or greater is imparted with a nitrocarburized hard layer. The nitrocarburized hard layer includes a surface compound layer suppressed to a thickness of 10 to 35 ?m, and a nitrogen diffusion zone below the surface compound layer having a diffusion depth of 700 ?m or greater. The steel includes C, Si, Mn, Cu, Ni, and Cr as the required elements and Mo, N, s-Al, and Ti as the optional elements.
    Type: Application
    Filed: December 2, 2010
    Publication date: June 9, 2011
    Applicants: HONDA MOTOR CO., LTD., DAIDO STEEL CO., LTD.
    Inventors: Isamu SAITO, Yoshihiro TAKITANI, Shinichiro KATO, Makoto HOBO, Keiichiro KAMIYA, Takahiro MIYAZAKI, Takashi KANO
  • Publication number: 20110115324
    Abstract: A bearing unit is provided which includes a shaft (51) to support rotatably, radial bearing (55) to support the shaft (51) circumferentially, a thrust bearing (66) to support the shaft (51) in the direction of thrusting, and a housing (56) having the radial bearing (55) and thrust bearing (66) disposed therein and in which a viscous fluid (57) is filled. The housing (56) has a sealed structure except for a shaft insertion hole (65) formed therein and through which the shaft 51 is introduced. Between the outer surface of the shaft (51) and the inner surface of the shaft insertion hole (65), there is defined a gap (69) having a sufficient width to prevent the viscous fluid (57) filled in the housing (56) from leaking out of the latter.
    Type: Application
    Filed: December 9, 2010
    Publication date: May 19, 2011
    Applicant: SONY CORPORATION
    Inventors: Yuji Shishido, Kenichiro Yazawa, Shinichiro Kato, Shuichi Kikuchi, Toru Ujiie
  • Publication number: 20100215658
    Abstract: The invention relates to antibodies and subsequences thereof that specifically bind to poxvirus B5R envelope protein, antibodies and subsequences thereof that specifically bind to pox virus H3L envelope protein, and combinations thereof.
    Type: Application
    Filed: October 6, 2008
    Publication date: August 26, 2010
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventor: SHINICHIRO KATO
  • Publication number: 20100196359
    Abstract: The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.
    Type: Application
    Filed: November 27, 2006
    Publication date: August 5, 2010
    Inventors: Shinichiro Kato, Rachel Soloff, Hitoshi Yoshida, Michael Croft
  • Publication number: 20100139451
    Abstract: The invention relates to a crankshaft member having high fatigue strength and good bending correctability, and its method of manufacture. The steel made crankshaft member mainly consists of a two-phase structure of ferrite and perlite. The steel includes C, Ni, Mn, and Cr as required elements and Si, Cu, Mo, Ti, V, Nb, Ca, and S as optional elements that may be included, in the amounts of C within the range of 0.20 to 0.50 wt %, Si within the range of 0 to 0.6 wt %, Mn within the range of 0.5 to 1.5 wt %, Cu within the range of 0 to 0.7 wt %, Ni within the range of 0.05 to 1.5 wt %, Cr within the range of 0.05 to 0.45 wt %, and Mo within the range of 0 to 0.5 wt % to satisfy the condition 115?70 C+8 Si+23 Mn+11 Cu+128 Cr+83 Mo?50. A portion of the member surface is provided at least with a hard nitride layer having an average hardness within the range of 300 to 450 HV. Lamellar spacing of the perlite is 0.3 ?m or less.
    Type: Application
    Filed: December 3, 2009
    Publication date: June 10, 2010
    Applicants: HONDA MOTOR CO., LTD., DAIDO STEEL CO., LTD.
    Inventors: Isamu SAITO, Yoshihiro Takitani, Shinichiro Kato, Makoto Hobo, Keiichiro Kamiya, Takahiro Miyazaki, Takashi Kano
  • Publication number: 20100021466
    Abstract: Provided herein are antibodies, such as fully human antibodies that immunospecifically bind to an hLIGHT polypeptide. Also provided are isolated nucleic acids encoding antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Further provided are vectors and host cells comprising nucleic acids encoding antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Also provided are methods of making antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Also provided herein is a method of treating a hLIGHT-mediated disease in a subject comprising administering to the subject an antibody, such as a fully human antibody, that immunospecifically binds to a hLIGHT polypeptide. In preferred embodiments, that anti-hLIGHT antibodies provided herein will ameliorate, neutralize or otherwise inhibit hLIGHT biological activity in vivo (e.g.
    Type: Application
    Filed: August 24, 2007
    Publication date: January 28, 2010
    Inventors: Steven W. Granger, Shinichiro Kato, Carl F. Ware
  • Publication number: 20090196872
    Abstract: Human, humanized and chimeric monoclonal antibodies that bind to influenza M2 protein. A human monoclonal antibody that binds to influenza M2 protein having different amino acid sequences. The antibodies are useful for, among other things, treatment, diagnostics, purifying and isolating M2 or influenza virus, and identifying the presence of M2 or influenza virus in a sample or a subject.
    Type: Application
    Filed: December 5, 2005
    Publication date: August 6, 2009
    Applicant: KIRIN BEER KABUSHIKI KAISHA
    Inventors: Shinichiro Kato, Rongfang Wang
  • Publication number: 20090162366
    Abstract: Human, humanized and chimeric monoclonal antibodies that bind to influenza M2 protein. The antibodies are useful for, among other things, treatment, diagnostics, purifying and isolating M2 or influenza virus, and identifying the presence of M2 or influenza virus in a sample or a subject.
    Type: Application
    Filed: February 28, 2008
    Publication date: June 25, 2009
    Applicant: KIRIN PHARMA KABUSHIKI KAISHA
    Inventors: Toshifumi Mikayama, Rongfang Wang, Shinichiro Kato
  • Publication number: 20080204281
    Abstract: An electronic key system includes an in-vehicle unit mounted in a vehicle and a portable unit. When a user leaves the vehicle, the in-vehicle unit requests information on a relative position of the vehicle relative to a landmark object near the vehicle from a vehicle navigation device and transmits received relative position information to the portable unit. The portable unit stores the received relative position information, and notifies of the stored relative position information according to a user's operation.
    Type: Application
    Filed: February 19, 2008
    Publication date: August 28, 2008
    Applicant: DENSO CORPORATION
    Inventors: Masahiro Sugiura, Hiromichi Naitoh, Munenori Matsumoto, Noriaki Okada, Shinichiro Kato, Tomoji Mabuchi, Haruyuki Ikeo, Masataka Okado, Kouichi Mizuno, Tomotsugu Sekine
  • Publication number: 20080169898
    Abstract: An in-vehicle device notifies a mobile device of a frequency channel which has been stored in its memory unit, and sets the notified channel to a reception channel. The mobile device transmits a reply signal through the channel notified from the in-vehicle device. When the in-vehicle device determines that a code included in the received reply signal is identical with a code specific to a vehicle, the in-vehicle device stores the channel used for receiving the reply signal in its memory unit. As a result, each communication is conducted through the same channel, which enabled the successful communication previously, thereby enhancing the certainty of communication.
    Type: Application
    Filed: January 10, 2008
    Publication date: July 17, 2008
    Applicant: DENSO CORPORATION
    Inventors: Shinichiro KATO, Masahiro SUGIURA, Kazuhiro NAKASHIMA
  • Publication number: 20070098589
    Abstract: A non-heat treated steel for hot forging and for a connecting rod, containing, in mass percent: 0.3 to 0.8% of C; 0.1 to 2.0% of Si; 0.5 to 1.5% of Mn; 0.01 to 0.15% of P; 1.0% or less of Cr; 0.4% or less of V; 0.05% or less of Al; 0.005 to 0.03% of N; and the balance Fe and inevitable impurities. The non-heat treated steel has a value E of not larger than 150, the value E being calculated from the following equation: E=2804?1549×Ceq?8862×P?23.4×H where H is a value of a Rockwell hardness of the connecting rod made of the non-heat treated steel; P is a phosphorus content (%) in the connecting rod; and Ceq is a value of a carbon equivalent.
    Type: Application
    Filed: October 25, 2006
    Publication date: May 3, 2007
    Inventors: Isseki Aihara, Yuuichi Yamada, Tomonori Miyazawa, Hideki Usuki, Yoshio Okada, Shinichiro Kato, Masakazu Hayaishi
  • Patent number: 7073946
    Abstract: A bearing unit is provided which includes a shaft (51) to support rotatably, radial bearing (55) to support the shaft (51) circumferentially, a thrust bearing (66) to support the shaft (51) in the direction of thrusting, and a housing (56) having the radial bearing (55) and thrust bearing (66) disposed therein and in which a viscous fluid (57) is filled. The housing (56) has a sealed structure except for a shaft insertion hole (65) formed therein and through which the shaft 51 is introduced. Between the outer surface of the shaft (51) and the inner surface of the shaft insertion hole (65), there is defined a gap (69) having a sufficient width to prevent the viscous fluid (57) filled in the housing (56) from leaking out of the latter. The housing (56) is formed as a one-piece structure by molding a synthetic resin.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: July 11, 2006
    Assignee: Sony Corporation
    Inventors: Yuji Shishido, Kenichiro Yazawa, Shinichiro Kato, Shuichi Kikuchi, Toru Ujiie