Abstract: A spread illuminating apparatus includes a plurality of LEDs, an FPC on which the plurality of LEDs are mounted, and a light guide plate. The FPC is fixed to an underside surface of the light guide plate using a double-sided tape, and the plurality of LEDs are disposed opposing an incident light surface of the light guide plate. The double-sided tape includes a white substrate that reflects light and a white adhesive layer that reflects light and is formed on a surface of the white substrate on a side opposing the light guide plate. The white adhesive layer is prepared by mixing a light reflecting substance into an adhesive. Thereby, the brightness and environmental resistance of the spread illuminating apparatus can be improved.

Abstract: A planar illumination device includes a light source unit, including a substantially planar emitting surface, configured to emit light to illuminate a substantially planar object, and a frame, formed in a frame shape enclosing the light source unit, disposed on an outer circumferential side of the light source unit, configured to hold the light source unit. The frame includes a reflecting part configured to reflect the light, and an absorbing part, formed integral with at least a part of an outer circumferential surface of the reflecting part, configured to absorb the light. The reflecting part and the absorbing part include joint interface therebetween that is inclined to a direction vertical to the emitting surface.

Abstract: Optical elements of a light guide plate are formed by repeatedly aligning convex parts in a longitudinal direction of the optical elements. Concave/convex shaped parts whose recess amount and/or protrusion amount are not constant are formed by three-dimensional curved surfaces that constitute the convex parts. An optical path of light that enters from an incident light surface of the light guide plate is modified by the concave/convex shaped parts that constitute the optical elements as the light progresses through the inside of the light guide plate, and thereby the light is diffused. Further, since the recess amount and/or protrusion amount of the concave/convex shaped parts are not constant, the optical path of light progressing through the inside of the light guide plate is modified randomly, and therefore a light diffusing effect is efficiently exhibited.

Abstract: A spread illuminating apparatus includes a plurality of LEDs, an FPC on which the plurality of LEDs are mounted, and a light guide plate. The FPC is fixed to an underside surface of the light guide plate using a double-sided tape, and the plurality of LEDs are disposed opposing an incident light surface of the light guide plate. The double-sided tape includes a white substrate that reflects light and a white adhesive layer that reflects light and is formed on a surface of the white substrate on a side opposing the light guide plate. The white adhesive layer is prepared by mixing a light reflecting substance into an adhesive. Thereby, the brightness and environmental resistance of the spread illuminating apparatus can be improved.

Abstract: A side-light type spread illuminating apparatus includes a light guiding plate; a light source arranged along a light entering face of the light guiding plate; a double-sided prism sheet arranged at a light emitted face side of the light guiding plate; and an optical member arranged at a back face side facing the light emitted face of the light guiding plate. The optical member includes a light absorption member allowing prevention of reflection of light that has been introduced into the optical member.

Abstract: A planar illumination device includes a light source unit, including a substantially planar emitting surface, configured to emit light to illuminate a substantially planar object, and a frame, formed in a frame shape enclosing the light source unit, disposed on an outer circumferential side of the light source unit, configured to hold the light source unit. The frame includes a reflecting part configured to reflect the light, and an absorbing part, formed integral with at least a part of an outer circumferential surface of the reflecting part, configured to absorb the light. The reflecting part and the absorbing part include joint interface therebetween that is inclined to a direction vertical to the emitting surface.

Abstract: A side-light type spread illuminating apparatus includes a light guiding plate; a light source arranged along a light entering face of the light guiding plate; a double-sided prism sheet arranged at a light emitted face side of the light guiding plate; and an optical member arranged at a back face side facing the light emitted face of the light guiding plate. The optical member includes a light absorption member allowing prevention of reflection of light that has been introduced into the optical member.

Abstract: A protein having amino acid sequence in SEQ ID No.:1 of the Sequence Listing derived from human MP52, and a dimer protein thereof. A homodimer protein described above can be obtained by constructing a plasmid containing DNA coding amino acid sequence in SEQ ID No.:1 of the Sequence Listing with a methionine at the N-terminus, introducing the plasmid into E. coli for transformation, solubilizing inclusion bodies obtained by culturing the transformant, purifying the monomer protein from the solubilized solution, refolding the monomer protein into a dimer protein and purifying the same. The homodimer protein described above is useful as a pharmaceutical composition for treating cartilage and bone diseases.

Abstract: A protein having amino acid sequence in SEQ ID No.:1 of the Sequence Listing derived from human MP52, and a dimer protein thereof. A homodimer protein described above can be obtained by constructing a plasmid containing DNA coding amino acid sequence in SEQ ID No.:1 of the Sequence Listing with a methionine at the N-terminus, introducing the plasmid into E. coli for transformation, solubilizing inclusion bodies obtained by culturing the transformant, purifying the monomer protein from the solubilized solution, refolding the monomer protein into a dimer protein and purifying the same. The homodimer protein described above is useful as a pharmaceutical composition for treating cartilage and bone diseases.

Abstract: This invention provides for a protein of the TGF-? superfamily in which the cysteine involved in the normal formation of homodimers is changed to another amino acid. These mutant proteins, as monomers, display higher bone morphogenetic activity than the wild-type protein dimers. Also provided is a method for producing and isolating these monomers by plasmid driven expression in various host systems including E. coli. In addition, the invention discloses the use of an agent containing purified monomers in preventing and treating diseases and problems affecting bone and/or cartilage.

Abstract: This invention provides for a protein of the TGF-? superfamily in which the cysteine involved in the normal formation of homodimers is changed to another amino acid. These mutant proteins, as monomers, display higher bone morphogenetic activity than the wild-type protein dimers. Also provided is a method for producing and isolating these monomers by plasmid driven expression in various host systems including E. coli. In addition, the invention discloses the use of an agent containing purified monomers in preventing and treating diseases and problems affecting bone and/or cartilage.

Abstract: A protein having amino acid sequence in SEQ ID NO: 1 of the Sequence Listing derived from human MP52, and a dimer protein thereof. A homodimer protein described above can be obtained by constructing a plasmid containing DNA coding amino acid sequence in SEQ ID NO: 1 of the Sequence Listing with a methionine at the N-terminus, introducing the plasmid into E. coli for transformation, solubilizing inclusion bodies obtained by culturing the transformant, purifying the monomer protein from the solubilized solution, refolding the monomer protein into a dimer protein and purifying the same. The homodimer protein described above is useful as a pharmaceutical composition for treating cartilage and bone diseases.

Abstract: A protein consisting of the amino acid sequence in SEQ ID No: 1 derived from human MP52 and a homodimer protein thereof useful for treating cartilage and/or bone diseases and a process for its preparation.

Abstract: This invention provides for a protein of the TGF-? superfamily in which the cysteine involved in the normal formation of homodimers is changed to another amino acid. These mutant proteins, as monomers, display higher bone morphogenetic activity than the wild-type protein dimers. Also provided is a method for producing and isolating these monomers by plasmid driven expression in various host systems including E. coli. In addition, the invention discloses the use of an agent containing purified monomers in preventing and treating diseases and problems affecting bone and/or cartilage.

Abstract: A throttle body (1) includes a throttle casing (2) and a motor casing (8). The throttle casing has a first main body (3) and a throttle valve (4) disposed within the first main body. The first main body is made of resin. The motor casing (8) has a second main body (9) and a motor (11) disposed within the second main body. The first main body and the second main body are formed separately from each other and are connected to each other via a joint device (27).

Abstract: An intake device for an internal combustion engine includes a throttle body (1) that forms an intake passage (1a). A throttle valve (2) is arranged within the intake passage. A pipe member (26) is connected to the throttle body, wherein the pipe member forms a communication passage (26a) communicating with the intake passage. An engagement device (53,63; 85,87; 92,63) is provided between the throttle body and the pipe member. The engagement device includes at least one engagement protrusion (53; 85; 92) and at least one engagement recess (63; 87M). When the engagement protrusion and the engagement recess are engaged with each other, detachment of the throttle body and the pipe member from each other is restricted. The assembly process is simplified by a lack of separate components such as clamps and bolts, relying instead upon a typical snap-fit connection.

Abstract: A memory mat is provided separately from a memory mat that is a normal memory area, and data therein cannot be read from the outside. In a page buffer, information input from the outside is stored. A comparing circuit compares security information stored in memory mat with information stored in page buffer, and the comparison result is output to the outside as a status. Even when unauthorized copying is performed, information in memory mat is not copied. Therefore, an external apparatus can easily determine whether or not the semiconductor memory is an unauthorized copy by referring to the status.

Abstract: This invention provides for a protein of the TGF-? superfamily in which the cysteine involved in the normal formation of homodimers is changed to another amino acid. These mutant proteins, as monomers, display higher bone morphogenetic activity than the wild-type protein dimers. Also provided is a method for producing and isolating these monomers by plasmid driven expression in various host systems including E. coli. In addition, the invention discloses the use of an agent containing purified monomers in preventing and treating diseases and problems affecting bone and/or cartilage.

Abstract: A throttle device includes a throttle body (1) and a cover (18) adapted to be mounted to the throttle body. A coupling device (13, 15; 51, 53) includes a first engaging portion (15; 51) disposed on one of the throttle body and the cover and a second engaging portion (13; 53) disposed on the other of the throttle body and the cover. The first and second engaging portions are engageable with each other when the throttle body and the cover is moved toward each other in a first direction, so that the throttle body and the cover are prevented from moving away from each other in a second direction opposite to the first direction. Means (1d; 1e: 53b) is provided for preventing accidental or unauthorized intentional access to the first or second engaging portions in order to disengage the first and second engaging portions.

Abstract: A throttle control device includes a throttle body (1). In the throttle body, an intake passage (1a), a first space (24a), and a second space (44) are formed. In the intake passage, a throttle valve (2) is rotatably arranged. The throttle valve is rotated by a motor (4). The motor is accommodated in the first space. The second space communicates with the first space. In addition, the second space is adjacent to the intake passage through the intermediation of a wall portion (20a). This makes it possible for the heat generated in the motor to be effectively dissipated from the first space into the intake passage via the second space and the wall portion.