Abstract: A monoclonal antibody is provided which binds to a human CC chemokine receptor 1 (CCR1) and inhibits activation of the human CCR1, or an antibody fragment thereof. The monoclonal antibody binds to an extracellular region of a human CCR1 and inhibits activation of the human CCR1 by a human CC chemokine ligand 15 (CCL15). An antibody fragment thereof, a hybridoma producing the antibody, a nucleic acid having a nucleotide sequence encoding the antibody or the antibody fragment, a transformant cell containing a vector containing the nucleic acid, a method for producing the antibody or the antibody fragment using the hybridoma or the transformant cell; a therapeutic agent and a diagnostic agent containing the antibody or the antibody fragment, and a method for treating and diagnosing a CCR1-related disease using the antibody or the antibody fragment are also provided.

Abstract: In a booster cable holding structure, a resin terminal supporting portion includes a tooth-edge surrounding wall on a pressed surface thereof to be pressed by a plurality of teeth arranged in a width direction of a pressing surface of a clip in a state the clip clamps a clamping connection portion, a wall inner surface of the tooth-edge surrounding wall closely surrounds each edge of at least two of the teeth of the clip or closely surrounds the edges of the at least two teeth together.

Abstract: In a booster cable holding structure, a resin terminal supporting portion includes a tooth-edge surrounding wall on a pressed surface thereof to be pressed by a plurality of teeth arranged in a width direction of a pressing surface of a clip in a state the clip clamps a clamping connection portion, a wall inner surface of the tooth-edge surrounding wall closely surrounds each edge of at least two of the teeth of the clip or closely surrounds the edges of the at least two teeth together.

Abstract: A wire connecting method and a wiring harness that allows one to utilize a single terminal for multiple core wires having various diameters thereby reducing the number and different types of terminals. The wire connecting method allows the larger wire cores first to be ultrasonic pressed such that the diameter of the larger core wires are reduced to sizes that are small enough to utilize the single terminal used on smaller core wires.

Abstract: [Technical Problem]An object of the present invention is to provide a wire connecting method and a wiring harness allowed to reduce the number of types of terminals for reducing cost by increasing the number of core wire sizes able to be crimped or press-connected with respect to one terminal. [Solution to Problem]Regarding covered wires 13, 14 of which core wire diameter is larger than the core wire diameter allowed to be crimped with a wire barrel 18, an ultrasonic processing in which while pressure is applied to a core wire 16, ultrasonic energy is applied to the core wire 16 is performed. Thereby, the core wire diameter is reduced to be allowed to be crimped to the wire barrel 18, and the core wire 16 of the covered wire 13, 14 is crimped or press-connected between a pair of crimping pieces 18B of the terminal 15.