Patents by Inventor Shinya Otsubo

Shinya Otsubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220096707
    Abstract: A hemostatic material includes a lipid that can accelerate adhesion or aggregation of platelets even if the lipid does not carry a protein or a peptide involved in adhesion or aggregation of platelets such as GPIb and H12 and, to achieve the object, provides a hemostatic material including a water-insoluble base and a lipid supported on a surface of the base, wherein the lipid includes one or two or more anionic lipids.
    Type: Application
    Filed: October 17, 2019
    Publication date: March 31, 2022
    Applicant: Toray Industries, Inc.
    Inventors: Shinji Takeoka, Keiko Nakahara, Mamoru Nishiura, Shinya Otsubo, Hajimu Kurumatani, Toru Arakane, Masanobu Takeda, Makoto Nakahara, Kumi Oyama
  • Publication number: 20210387943
    Abstract: A carboxylic acid-type lipid can accelerate adhesion or aggregation of platelets even if the carboxylic acid-type lipid does not carry a protein involved in adhesion or aggregation of platelets or a peptide corresponding to an active site of the protein; a lipid particle and a lipid membrane each include the carboxylic acid-type lipid; and a platelet aggregation accelerating agent, a platelet adhesion accelerating agent, a hemostatic agent and a platelet substitute each include the carboxylic acid-type lipid, the lipid particle or the lipid membrane. A carboxylic acid-type lipid is selected from carboxylic acid-type lipids represented by formulas (I) to (VI), a lipid particle includes the carboxylic acid-type lipid, a lipid membrane includes the carboxylic acid-type lipid, and a platelet aggregation accelerating agent, a platelet adhesion accelerating agent, a hemostatic agent and a platelet substitute each include the carboxylic acid-type lipid, the lipid particle or the lipid membrane.
    Type: Application
    Filed: October 17, 2019
    Publication date: December 16, 2021
    Inventors: Shinji Takeoka, Keiko Nakahara, Mamoru Nishiura, Shinya Otsubo, Hajimu Kurumatani, Toru Arakane
  • Patent number: 10213530
    Abstract: A polymer film can be adjusted to movement or a fine uneven surface of a living body and has excellent ability to adhere to a biological tissue. The polymer film includes a block copolymer having a structure in which branched polyalkylene glycol and polyhydroxyalkanoic acid are bound to each other, wherein the polymer film has a film thickness of 10 to 1000 nm. The branched polyalkylene glycol has at least three terminal hydroxyl groups per molecule, the mass percentage of the branched polyalkylene glycol relative to the total mass of the block copolymer is 1% to 30%, and a value obtained by dividing the average molecular weight of polyhydroxyalkanoic acid in the block copolymer by X that is the number of terminal hydroxyl groups present per a single molecule of the branched polyalkylene glycol is 10000 to 30000.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: February 26, 2019
    Assignees: Toray Industries, Inc., Nanotheta Co, Ltd.
    Inventors: Akihiro Saito, Toru Arakane, Kazuhiro Tanahashi, Koji Okabayashi, Shinji Takeoka, Toshinori Fujie, Shoichiro Suzuki, Atsushi Murata, Shinya Otsubo
  • Publication number: 20170348465
    Abstract: A polymer film can be adjusted to movement or a fine uneven surface of a living body and has excellent ability to adhere to a biological tissue. The polymer film includes a block copolymer having a structure in which branched polyalkylene glycol and polyhydroxyalkanoic acid are bound to each other, wherein the polymer film has a film thickness of 10 to 1000 nm. The branched polyalkylene glycol has at least three terminal hydroxyl groups per molecule, the mass percentage of the branched polyalkylene glycol relative to the total mass of the block copolymer is 1% to 30%, and a value obtained by dividing the average molecular weight of polyhydroxyalkanoic acid in the block copolymer by X that is the number of terminal hydroxyl groups present per a single molecule of the branched polyalkylene glycol is 10000 to 30000.
    Type: Application
    Filed: June 17, 2016
    Publication date: December 7, 2017
    Applicants: Toray Industries, Inc., Nanotheta Co., Ltd.
    Inventors: Akihiro Saito, Toru Arakane, Kazuhiro Tanahashi, Koji Okabayashi, Shinji Takeoka, Toshinori Fujie, Shoichiro Suzuki, Atsushi Murata, Shinya Otsubo
  • Patent number: 9709341
    Abstract: Provided are a heat exchanger that does not impede downsizing and removes water in the heat absorbing pipe adequately with a simple configuration even when the reduction in diameter of the heat absorbing pipe is made. A heat exchanger 5 in which heat absorbing pipes 51 are disposed in a multi-tier arrangement within a casing 50 which is the passage of combustion exhaust gas, both pipe ends 511,512 of each of the heat absorbing pipes 51 are connected respectively to two headers 54, 55 provided on a side plate 52 of the casing 50, and water introduced from an external pipe 63 to each of the heat absorbing pipes 51 through the header 54 is heat-exchanged and heated by combustion exhaust gas. The pipe ends 511, 512 of the heat absorbing pipes 51 are arranged at a predetermined vertical interval.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: July 18, 2017
    Assignee: RINNAI CORPORATION
    Inventors: Hidekatsu Naruse, Yoichi Kojima, Shinya Otsubo, Masaru Shimazaki, Takeshi Kawashima, Hiroaki Sasaki
  • Publication number: 20130264037
    Abstract: A latent heat exchanger (1) has a casing (2), a heat-absorbing tube (50) accommodated in the casing (2), an inlet header (60), and an outlet header (70). The casing (2) has a casing main body (10) and a top plate (40) closing an upper opening (16) of the casing main body (10). The back wall (11), the front wall (12), the bottom wall (13), one side wall (14), and the other side wall (15) of the casing main body (10) are formed integrally by draw-processing a single metal plate.
    Type: Application
    Filed: November 18, 2011
    Publication date: October 10, 2013
    Applicant: RINNAI CORPORATION
    Inventors: Shinya Otsubo, Hidekatsu Naruse, Yoichi Kojima
  • Publication number: 20130112384
    Abstract: Provided are a heat exchanger that does not impede downsizing and removes water in the heat absorbing pipe adequately with a simple configuration even when the reduction in diameter of the heat absorbing pipe is made. A heat exchanger 5 in which heat absorbing pipes 51 are disposed in a multi-tier arrangement within a casing 50 which is the passage of combustion exhaust gas, both pipe ends 511,512 of each of the heat absorbing pipes 51 are connected respectively to two headers 54, 55 provided on a side plate 52 of the casing 50, and water introduced from an external pipe 63 to each of the heat absorbing pipes 51 through the header 54 is heat-exchanged and heated by combustion exhaust gas. The pipe ends 511, 512 of the heat absorbing pipes 51 are arranged at a predetermined vertical interval.
    Type: Application
    Filed: April 26, 2010
    Publication date: May 9, 2013
    Applicant: RINNAI CORPORATION
    Inventors: Hidekatsu Naruse, Yoichi Kojima, Shinya Otsubo, Masaru Shimazaki, Takeshi Kawashima, Hiroaki Sasaki