Patents by Inventor Shinzo Isojima

Shinzo Isojima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genes encoding porcine zona pellucida protein PZP-4, expression thereof and contraceptive vaccines comprising expressed (poly) peptides
    Patent number: 5348866
    Abstract: This invention relates to a DNA sequence comprising at least part of a porcine zona pellucida PZP-4.alpha. or -4.beta. gene coding for an amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 2, respectively, in SEQUENCE LISTING.This invention also relates to an expression system and to expression of said DNA.In addition, this invention relates to an immunogenic recombinant polypeptide or peptide which comprises at least part of said amino acid sequence and which is obtained by expressing said DNA, and to a contraceptive vaccine for use in human or other animals which comprises said polypeptide or peptide as an active ingredient.
    Type: Grant
    Filed: March 20, 1992
    Date of Patent: September 20, 1994
    Assignees: Shinzo Isojima, Tonen Corporation
    Inventors: Shinzo Isojima, Akiko Akatani, Yuichi Okazaki, Masanobu Sugimoto
  • Monoclonal antibody NUH2 capable of inactivating motility of human sperm, antigen defined by said monoclonal antibody and methods of using said monoclonal antibody and antigen
    Patent number: 5227160
    Abstract: Monoclonal antibody NUH2 produced by a hybridoma having ATCC deposit no. HB 9762. An isolated antigen capable of specifically binding to anti-human sperm antibodies including NUH2 and comprising at least an epitope having a sialyl I structure, and any analogues derived from said antigen. Methods of using the monoclonal antibody and antigen for contraception and treating infertility in human females.
    Type: Grant
    Filed: July 15, 1988
    Date of Patent: July 13, 1993
    Assignees: The Biomembrane Institute, Hyogo Medical College
    Inventors: Edward Nudelman, Tokio Kaizu, Ulla Mandel-Clausen, Steven B. Levery, Sen-itiroh Hakomori, Yoshiyuki Tsuji, Shinzo Isojima