Abstract: The present invention relates to leukotriene A4 hydrolase inhibitors containing compounds represented by the formula [I] or salts thereof as active ingredients, wherein R1 represents hydrogen, alkyl, phenylalkyl, alkanoyl or benzoyl; R2 and R3 each represent hydrogen or alkyl; R4 represents hydroxyl, alkoxy, phenylalkoxy, amino, alkylamino or phenylalkylamino; R5 represents phenylalkyl or naphthylalkyl; “Z” represents sulfur or oxygen; “A” represents alkylene; and “n” represents 0, 1 or 2; providing that the phenyl ring in R1 can be substituted by alkyl, alkoxy or halogen, and that the phenyl ring or the naphthyl ring in R5 can be substituted by alkyl, cycloalkyl, alkoxy, alkylthio or halogen.

Abstract: A method for the healing of wounds caused by corneal injury, which includes administering to a mammalian patient in need thereof an effective wound healing amount of lactoferrin, lactoperoxidase or a combination of lactoferrin and lactoperoxidase as active ingredients, either alone or in admixture with at least one excipient.

Abstract: This invention offers novel compounds of the formula [I] which are useful for treatment of various immune diseases such as immunodeficiency and autoimmune diseases caused by immuno disorders, and synthetic intermediates thereof represented by the formula [II], ##STR1## wherein X is oxygen or NR.sup.7 and the R.sub.1 -R.sub.7 groups are defined in the specification.

Abstract: A compound of the formula [I]. ##STR1## The compounds of this invention has excellent thymulin-line activities and expected to be useful for treatment of various diseases such as immunodeficiency and autoimmune diseases.

Abstract: This invention relates to cysteine derivatives of the formula[I] and salts thereof. ##STR1## The compounds of this invention are useful for immunomodulator and treatment of liver disorder.

Abstract: A compound of the formula [I] and pharmaceutically acceptable salts thereof; and a synthetic intermediate represented by the formula [II] and pharmaceutically acceptable salts thereof, ##STR1## wherein R 1 is hydrogen or lower alkyl;R 2 is hydrogen or a protective group of thiol;R 3 is hydroxy, a remainder of ester group or a remainder of amido group;A is straight or branched lower alkylene, andthe sulfur atom in the side chain may be directly join with --CO-- to conform a thiolactone ring.The compounds of this invention have excellent thymulin-like activities and are expected to be useful for treatment of various immune disorders such as immunodeficiency and autoimmune diseases.

Abstract: This invention relates to a photostabilizing method for ophthalmic solutions and the resulting ophthalmic solutions therefrom. The stabilization is attained by adding polyhydric alcohol and boric acid, and/or sodium borate to ophthalmic solutions which contain a drug substance unstable against light.

Abstract: Compounds of the formula [I] and salts thereof, which are useful for treatment of liver disorders, ##STR1## wherein X is oxygen or sulfur; andA is straight C.sub.3 -C.sub.4 alkylene which can be substituted by one or more lower alkyl groups.

Abstract: This invention relates to novel compounds of the formula [I], which are useful for treatment of various diseases such as immunodeficiency and autoimmune diseases caused by immune disorders, processes for preparing the compounds and compositions containing the compounds as active ingredients.

Abstract: This invention relates to the compounds of the formula [I] and salts thereof, which are useful for treatment of liver disorders, ##STR1## wherein X is oxygen or sulfur;R.sup.1 is lower alkyl which can be substituted by hydroxy, carboxy or lower alkoxycarbonyl;R.sup.2 is hydrogen, lower alkanoyl, phenyl lower alkanoyl or phenyl lower alkyl, and said phenyl ring of phenyl lower alkanoyl or phenyl lower alkyl can be substituted by lower alkyl or lower alkoxy; andA is straight or branched C.sub.1 -C.sub.6 alkylene.

Abstract: This invention relates to the compounds of the formula [I] and salts thereof, which are useful for treatment of liver disorders, ##STR1## wherein X is oxygen or sulfur; andA is straight C.sub.2 alkylene which can be substituted by one or more lower alkyl.

Abstract: This invention relates to cyclic sulfur-containing compounds of the formula [I] and salts thereof which are useful for immunomodulator and treatment of liver diseases.

Abstract: A pharmaceutical composition for treatment of an autoimmune disease, which comprises (i) a pharmaceutical carrier and (ii) a compound of the formula (I) or pharmaceutically acceptable salts thereof in an amount effective for treatment of an autoimmune disease, ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each is lower alkyl; and R.sup.3 is hydrogen or lower alkyl.

Abstract: Cyclic sulfur-containing compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each is hydrogen or lower alkyl,R.sup.3 is hydrogen or lower alkyl,X is S--S,m is 0 or 1 andn is 1 or 2, with the proviso that when m is 0,n is 2, and pharmaceutically acceptable salts thereof.Such compounds are useful for treating liver disorders and autoimmune diseases.