Patents by Inventor Shivaprasad Shankaramma

Shivaprasad Shankaramma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Template-fixed peptidomimetics with antimicrobial activity
    Patent number: 7855179
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula (I), wherein Z is a template-fixed chain of 12 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly or Pro, or of certain types, at least one of these residues being of the type of N-substituted glycines, which types, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to inhibit the growth of or to kill microorganisms. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials or as medicaments to treat or prevent infections. These ?-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and solution phase synthetic strategy.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: December 21, 2010
    Assignees: Polyphor Ltd., Universität Zürich
    Inventors: Jan Wim Vrijbloed, Daniel Obrecht, John Anthony Robinson, Sergio Locurio, Frank Gombert, Christian Ludin, Alexander Lederer, Shivaprasad Shankaramma
  • Template-fixed peptidomimetics with antimicrobial activity
    Publication number: 20070054840
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula (I), wherein Z is a template-fixed chain of 12 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly or Pro, or of certain types, at least one of these residues being of the type of N-substituted glycines, which types, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to inhibit the growth of or to kill microorganisms. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials or as medicaments to treat or prevent infections. These ?-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and solution phase synthetic strategy.
    Type: Application
    Filed: October 2, 2002
    Publication date: March 8, 2007
    Inventors: Jan Vrijbloed, Daniel Obrecht, John Robinson, Sergio Locurio, Frank Gombert, Christian Ludin, Alexander Lederer, Shivaprasad Shankaramma