Patents by Inventor Shoei-Yn Lin-Shiau

Shoei-Yn Lin-Shiau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11197904
    Abstract: The present invention relates to the area of pharmaceutical compositions. More particularly, the present invention relates to a series of pharmaceutical compositions (PTM) containing phyto-polyphenols (P), clinical drugs with selective targets (T) and a metal ions (M) and the methods thereof for use in prevention and therapy of infectious diseases, neurodegenerative diseases, dementia, diabetes, obesity, metabolic syndromes, osteoporosis, cancers and/or chronic pain.
    Type: Grant
    Filed: January 20, 2019
    Date of Patent: December 14, 2021
    Assignees: Chung Shan Medical University
    Inventor: Shoei-Yn Lin-Shiau
  • Publication number: 20190224266
    Abstract: The present invention relates to the area of pharmaceutical compositions. More particularly, the present invention relates to a series of pharmaceutical compositions (PTM) containing phyto-polyphenols (P), clinical drugs with selective targets (T) and a metal ions (M) and the methods thereof for use in prevention and therapy of infectious diseases, neurodegenerative diseases, dementia, diabetes, obesity, metabolic syndromes, osteoporosis, cancers and/or chronic pain.
    Type: Application
    Filed: January 20, 2019
    Publication date: July 25, 2019
    Inventor: SHOEI-YN LIN-SHIAU
  • Publication number: 20170246233
    Abstract: The invention relates to a method of decreasing blood sugar by inhibition of ?-glucosidase activity in a subject in need thereof, comprising administering pu-erh tea polysaccharides (PTPS) to the subject, wherein the active ingredients in PTPS are neutral sugar, protein, polyphenol, and uronic acids.
    Type: Application
    Filed: February 26, 2016
    Publication date: August 31, 2017
    Applicant: Chung Shan Medical University
    Inventors: Shoei-Yn Lin-Shiau, Jen-Kun Lin
  • Patent number: 9011945
    Abstract: The present invention discloses the combined treatment of memantine (N-methyl-D-aspartate receptor antagonist) and tea polyphenol (an antioxidant and anti-inflammatory agent) is more effective (synergistic) in neuroprotection than either memantine or tea polyphenol alone in mouse excitotoxic injury. These findings provide useful information about the potential application of memantine and tea polyphenols in preventing or treating clinical excitotoxic injury such as brain trauma, brain ischemia, epilepsy, and Alzheimer's disease.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: April 21, 2015
    Assignee: National Taiwan University
    Inventors: Shoei-Yn Lin-Shiau, Jen-Kun Lin
  • Publication number: 20140094513
    Abstract: The present invention discloses the combined treatment of memantine (N-methyl-D-aspartate receptor antagonist) and tea polyphenol (an antioxidant and anti-inflammatory agent) is more effective (synergistic) in neuroprotection than either memantine or tea polyphenol alone in mouse excitotoxic injury. These findings provide useful information about the potential application of memantine and tea polyphenols in preventing or treating clinical excitotoxic injury such as brain trauma, brain ischemia, epilepsy, and Alzheimer's disease.
    Type: Application
    Filed: December 3, 2013
    Publication date: April 3, 2014
    Applicant: NATIONAL TAIWAN UNVERSITY
    Inventors: SHOEI-YN LIN-SHIAU, JEN-KUN LIN
  • Publication number: 20120115943
    Abstract: The present invention discloses the combined treatment of memantine (N-methyl-D-aspartate receptor antagonist) and tea polyphenol (an antioxidant and anti-inflammatory agent) is more effective (synergistic) in neuroprotection than either memantine or tea polyphenol alone in mouse excitotoxic injury. These findings provide useful information about the potential application of memantine and tea polyphenols in preventing or treating clinical excitotoxic injury such as brain trauma, brain ischemia, epilepsy, and Alzheimer's disease.
    Type: Application
    Filed: January 12, 2012
    Publication date: May 10, 2012
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Shoei-Yn Lin-Shiau, Jen-Kun Lin
  • Publication number: 20100081722
    Abstract: The present invention discloses the combined treatment of memantine (N-methyl-D-aspartate receptor antagonist) and tea polyphenol (an antioxidant and anti-inflammatory agent) is more effective (synergistic) in neuroprotection than either memantine or tea polyphenol alone in mouse excitotoxic injury. These findings provide useful information about the potential application of memantine and tea polyphenols in preventing or treating clinical excitotoxic injury such as brain trauma, brain ischemia, epilepsy, and Alzheimer's disease.
    Type: Application
    Filed: October 1, 2008
    Publication date: April 1, 2010
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Shoei-Yn Lin-Shiau, Jen-Kun Lin