Abstract: The present disclosure relates to a photodetection device and an electronic apparatus that allow for reducing surface reflection from an on-chip microlens and suppressing deterioration of image quality. Provided is a photodetection device including: a plurality of pixels that have photoelectric conversion units; on-chip microlenses that are formed in such a way as to correspond to the individual pixels; and an antireflection film that is formed on a surface of the on-chip microlens, in which the antireflection film is constituted by a stacking of: a first inorganic film that is formed by a metal oxide film; and a second inorganic film that is formed on a surface of the first inorganic film and has a lower refractive index than the first inorganic film. The present disclosure can be applied to, for example, a CMOS solid-state imaging device.

Abstract: Sedoheptulose, which is a saccharide falling within the categories of ketoses and heptuloses, is one of a small number of heptuloses occurring in nature. Provided are a method for producing sedoheptulose using a bacterium owing to the deletion or attenuation of a specific enzymatic function, a method for improving the productivity of sedoheptulose by the bacterium, and the bacterium.

Abstract: Sedoheptulose, which is a saccharide falling within the categories of ketoses and heptuloses, is one of a small number of heptuloses occurring in nature. A method for producing sedoheptulose may use a bacterium, and/or may improve the productivity of sedoheptulose by the bacterium, and the bacterium. To solve this problem, provided are a method for producing sedoheptulose using a bacterium owing to the deletion or attenuation of a specific enzymatic function, a method for improving the productivity of sedoheptulose by the bacterium, and the bacterium.

Abstract: The invention relates to a metabolic enzyme-disrupted aerobic strain and a method for culturing the strain. The present invention provides, for example, a culture comprising a culture medium that has been cultured under an aerobic condition, wherein the culture medium contains an aerobe, wherein the aerobe has a disrupted gene encoding a metabolic enzyme of glycolysis selected from the group consisting of the metabolic enzymes of glycolysis except hexokinase, thereby suppressing metabolism from a carbon source (e.g., glucose) to the TCA cycle in the aerobe.

Abstract: Sedoheptulose, which is a saccharide falling within the categories of ketoses and heptuloses, is one of a small number of heptuloses occurring in nature. A method for producing sedoheptulose may use a bacterium, and/or may improve the productivity of sedoheptulose by the bacterium, and the bacterium. To solve this problem, provided are a method for producing sedoheptulose using a bacterium owing to the deletion or attenuation of a specific enzymatic function, a method for improving the productivity of sedoheptulose by the bacterium, and the bacterium.

Abstract: Provided are: a method for producing a mycrosporine-like amino acid (MAA) that includes a step in which microbes are cultivated that produce MAA on the outside of bacterial cells, a step in which the bacterial cells and extracellular culture fluid are separated, and a step in which the MAA is recovered from the extracellular culture fluid; an MAA indicated by formula (1), an MAA produced using this method, or an ultraviolet-absorbing composition including the MAA indicated by formula (1); and a composition including the MAA produced using this method or the MAA indicated by formula (1), for preventing at least one symptom or disease selected from a group comprising acute skin reactions, aging of the skin, and skin cancer.

Abstract: Provided are: a method for producing a mycrosporine-like amino acid (MAA) that includes a step in which microbes are cultivated that produce MAA on the outside of bacterial cells, a step in which the bacterial cells and extracellular culture fluid are separated, and a step in which the MAA is recovered from the extracellular culture fluid; an MAA indicated by formula (1), an MAA produced using this method, or an ultraviolet-absorbing composition including the MAA indicated by formula (1); and a composition including the MAA produced using this method or the MAA indicated by formula (1), for preventing at least one symptom or disease selected from a group comprising acute skin reactions, aging of the skin, and skin cancer.

Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.

Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.

Abstract: A method for manufacturing a novel tilt alignment type optical compensation film formed using a non-liquid crystal polymer material, instead of a conventional tilt alignment type optical compensation film using a liquid crystal material. The method for manufacturing including: melting a non-liquid crystal polymer to prepare a molten resin; applying a shear force to the melted non-liquid crystal polymer by a shear force application device, thereby forming a film having an optical axis that tilts with respect to a thickness direction of the film; and stretching the film. The step of forming the film is carried out under conditions where a temperature T3 of the melted non-liquid crystal polymer, a glass transition point Tg of the non-liquid crystal polymer, and a temperature T2 of the shear force application device satisfy relationships represented by the following formulae (A) and (B): T3>Tg+25° C.; and??(A) T3>T2.

Abstract: Provided is an optical pickup device capable of ensuring the compatibility among three types of optical discs, i.e., BDs, DVDs, and CDs, with a common objective lens and, in addition, capable of ensuring a sufficient working distance for CDs, and also provided are an optical information recording and reproducing device and an objective lens suitable for the optical information recording and reproducing device. On the objective lens, there is arranged a first optical path difference providing structure formed such that: the direction of step differences of a basic structure wherein the diffraction order of a blue-violet laser light flux become an odd order faces toward the opposite direction of the optical axis; the direction of step differences of a basic structure wherein the diffraction order of the blue-violet laser light flux become an even order faces toward the optical axis; and both the basic structures are overlapped together.

Abstract: To provide a dental implant abutment made of titanium, which is mounted on the intraoral side of a dental implant fixture embedded in a jawbone and coming to be an artificial tooth root, penetrates through gingiva, and comes to be a base of an upper structure. The dental implant abutment does not remarkably impair aesthetic property even when the intraoral portion of the dental implant abutment is seen through gingiva. The surface of the dental implant abutment made of titanium is colored to have the value of L* within a range from 40 to 44, the value of a* within a range from 21 to 40 and the value of b* within a range from ?20 to 10, which are represented by L*a*b* color system.

Abstract: Provided is an objective lens that enables the suppression of molding defects in a high NA lens, and an optical pickup device. As the objective lens (OBJ) includes a thick-flange section (FT), a thick-flange-section forming section (11c) can be formed on a first-flange-section transfer surface (11b) of a first mold (10) so as to connect to a gate section (GT), as shown in FIG. 2. Thereby, the cross sectional area of the gate section (GT) is increased, which allows optimizing the gate seal time, applying sufficient pressure, and effectively removing air.

Abstract: Provided is an optical pickup device capable of ensuring the compatibility among three types of optical discs, i.e., BDs, DVDs, and CDs, with a common objective lens and, in addition, capable of ensuring a sufficient working distance for CDs, and also provided are an optical information recording and reproducing device and an objective lens suitable for the optical information recording and reproducing device. On the objective lens, there is arranged a first optical path difference providing structure formed such that: the direction of step differences of a basic structure wherein the diffraction order of a blue-violet laser light flux become an odd order faces toward the opposite direction of the optical axis; the direction of step differences of a basic structure wherein the diffraction order of the blue-violet laser light flux become an even order faces toward the optical axis; and both the basic structures are overlapped together.

Abstract: The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation.

Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.

Abstract: The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation.

Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.

Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.

Abstract: An objective lens unit, includes: an objective lens for irradiating and converging laser light on an optical disc as an a light information recording medium; and a lens frame for retaining the objective lens, wherein the lens frame is structured so that at least a portion closer to a rotation center of the optical disc is offset to an inner side of the lens frame with regards to a virtual edge section closer to the rotation center of the optical disc, wherein the virtual edge section is in a nodal line of a virtual plane that includes an end face which is closest to the optical disc in the lens frame and the objective lens, and that is perpendicular to an optical axis and a virtual rotation curved surface that is obtained when a virtual straight line passing a portion which is farthest from the optical axis in the lens frame and the objective lens, in parallel with the optical axis, is rotated around the optical axis as a center axis.