Abstract: The current application describes various compositions and methods for the production of FN3-based binding proteins with improved stability properties. Aspects of the disclosure relate to polypeptides comprising a variant fibronectin type III (FN3) domain from Sulfolobus tokodaii or Pyrococcus horikoshii comprising one or more amino acid substitutions or insertions in a loop region of FN3, in a non-loop region of FN3, or in both.

Abstract: A liquid discharge apparatus is provided, including a liquid discharge head including: an upper substrate, a plurality of piezoelectric elements, an intermediate substrate, a lower substrate and a plurality of individual traces arranged on the upper substrate and extending toward the contacts arranged on the one end side in the second direction from the plurality of piezoelectric elements respectively.

Abstract: A liquid discharge head includes: an individual channel having an inlet and an outlet, the individual channel including: a nozzle, an upstream-side pressure chamber arranged between the inlet and the nozzle, a downstream-side pressure chamber arranged between the outlet and the nozzle, an upstream-side throttle channel connecting the inlet and the upstream-side pressure chamber, and a downstream-side throttle channel connecting the outlet and the downstream-side pressure chamber; a supply channel connected to the inlet and configured to supply liquid to the individual channel; a recovery channel connected to the outlet and configured to recover the liquid from the individual channel; an upstream-side actuator configured to apply pressure to the liquid inside the upstream-side pressure chamber; and a downstream-side actuator configured to apply the pressure to the liquid inside the downstream-side pressure chamber.

Abstract: A liquid discharge head includes: first and second common channels extending in a first direction; and individual channels including pressure chambers and nozzles. Each of the individual channels includes: a supply portion; a descender portion extending in a second direction; and a return portion extending in a third direction. The return portion includes: a throttle portion; and a wide portion. Each of the nozzles overlaps with the wide portion. A relationship of L2>L1 is satisfied, wherein L1 is a distance in the third direction from a center of each of the nozzles to a throttle starting position, and L2 is a distance in the third direction passing through a center in a cross section of the descender portion and ranging from a center line parallel to the second direction to the center of each of the nozzles.

Abstract: A liquid discharge head includes an individual channel, a supply channel in communication with an inlet of the individual channel, and a return channel in communication with an outlet of the individual channel. The supply channel extends in a channel longitudinal direction, and communicates with a retaining chamber for retaining liquid via a supply port provided at one side with respect to the individual channel in the channel longitudinal direction. The return channel extends in the channel longitudinal direction, and communicates with the retaining chamber via a return port provided at the one side with respect to the individual channel in the channel longitudinal direction. The inlet and the outlet are located at the same position in the channel longitudinal direction.

Abstract: A liquid discharge head includes: individual channels; a supply channel connected to inlets of the individual channels and through which liquid is supplied to the individual channels; and a recovery channel connected to outlets of the induvial channels and through which the liquid is recovered from the individual channels. Each of the induvial channels includes: a nozzle; an upstream-side pressure chamber disposed between the nozzle and the supply channel; a downstream-side pressure chamber disposed between the nozzle and the recovery channel; an upstream-side throttle channel connecting the supply channel and the upstream-side pressure chamber; and a downstream-side throttle channel connecting the recovery channel and the downstream-side pressure chamber. A channel resistance of the upstream-side throttle channel is smaller than a channel resistance of the downstream-side throttle channel.

Abstract: A liquid discharging head includes: a first member having a surface in which first openings are formed, the first openings arranged in a first direction and communicating with individual channels; a second member disposed at one side in a second direction with respect to the first member, the second member having: a space extending in the first direction and communicating with the first openings; and a second opening disposed at the first side in the second direction with respect to the space and communicating with the space; and a third member disposed between the first member and the second member in the second direction and having a communicating hole extending in the first direction and allowing the first openings to communicate with the space. The third member has a wall dividing the communicating hole into partial holes separated from each other in the first direction.

Abstract: There is provided a liquid discharge head including a channel unit including: individual channels aligned in a first direction, and first and second common channels extending in the first direction. Each of the individual channels includes: a nozzle, a pressure chamber, first and second communicating channels. The channel unit further includes a linking channel linking two pieces of the second communicating channel to each other.

Abstract: A liquid ejection head includes a nozzle, a pressure chamber configured to receive a pressure to eject liquid from the nozzle, a descender, and a communication channel. The descender has a first end and a second end opposite to each other. The first end is connected to the pressure chamber. The communication channel is connected to the second end and extends from a connection with the second end in an X direction. A first direction in which the descender extends from the second end toward the first end is inclined toward the communication channel relative to a Y direction orthogonal to the X direction.

Abstract: There is provided a liquid discharge head including a channel member and a temperature sensor. The channel member includes: a plurality of individual channels aligned in a first direction; a first common channel extending in the first direction and communicating with the plurality of individual channels; a second common channel extending in the first direction, communicating with the plurality of individual channels and arranged side by side to the first common channel in a second direction crossing the first direction; and a connecting channel extending in the second direction and connecting an end in the first direction of the first common channel and an end in the first direction of the second common channel. The temperature sensor overlaps with the connecting channel in the second direction.

Abstract: A liquid jetting apparatus includes a nozzle plate having a nozzle, and a channel unit having a first surface facing and joined with the nozzle plate. The channel unit has a first channel member having the first surface, and a second channel member having a second surface facing and joined with the first channel member. The second channel member is formed with a first pressure chamber, a second pressure chamber, a first opening and a second opening defined by the second surface, a first connecting channel connecting the first pressure chamber and the first opening, and a second connecting channel connecting the second pressure chamber and the second opening. The first channel member is formed with a third connecting channel connecting the first pressure chamber and the second pressure chamber.

Abstract: A liquid ejection head includes a stack structure including plates stacked and bonded with an adhesive agent, individual channels formed in the stack structure, dummy channels formed in the stack structure separately from the individual channels, and a first relief groove formed in the stack structure separately from the individual channels and configured to trap therein an excessive adhesive agent. Each individual channel includes a pressure chamber to which pressure is applied for liquid ejection form a nozzle, a supply throttle channel connected to the pressure chamber, and a return throttle channel communicating with the pressure chamber. The supply throttle channel and the return throttle channel each have a smaller cross-sectional area than the pressure chamber. The dummy channels include dummy chambers arranged laterally to an array of the pressure chambers arranged in an array direction. The first relief groove is connected to the dummy channels.

Abstract: A liquid ejection head includes a supply manifold, a return manifold, and individual channels each connected, at its upstream end, to the supply manifold and, at its downstream end, to the return manifold. Each of the individual channels communicates with a corresponding one of nozzles arranged in an array on a nozzle surface. The supply manifold and the return manifold extend in an extending direction along the nozzle array. The return manifold includes a lower portion located below the supply manifold to overlap the supply manifold in plan view orthogonal to the nozzle surface, and a standing portion located at at least one of opposite ends of the lower portion in the extending direction to be outside the supply manifold in plan view. The standing portion has a height to cover at least a portion of an end of the supply manifold when viewed in the extending direction.

Abstract: A liquid ejection head includes a supply manifold, a return manifold, a plurality of individual channels, and a connecting throttle channel. The supply manifold includes a supply port through which liquid is supplied from an exterior. The return manifold includes a return port through which liquid is discharged to the exterior. Each individual channel is connected, at an upstream end thereof, to the supply manifold and, at a downstream end thereof, to the return manifold. Each individual channel communicates with a corresponding one of nozzles and includes an individual throttle channel. Through the connecting throttle channel, adjacent ones of the individual throttle channels communicate with each other. The connecting throttle channel has a channel resistance less than or equal to a channel resistance of each individual throttle channel.

Abstract: A liquid jetting apparatus includes a nozzle plate having a nozzle, and a channel unit having a first surface facing and joined with the nozzle plate. The channel unit has a first channel member having the first surface, and a second channel member having a second surface facing and joined with the first channel member. The second channel member is formed with a first pressure chamber, a second pressure chamber, a first opening and a second opening defined by the second surface, a first connecting channel connecting the first pressure chamber and the first opening, and a second connecting channel connecting the second pressure chamber and the second opening. The first channel member is formed with a third connecting channel connecting the first pressure chamber and the second pressure chamber.

Abstract: A liquid discharge head includes: a channel member having a nozzle surface and a back surface disposed separately from the nozzle surface, the channel member formed having nozzles arranged in the nozzle surface, individual channels connected to the nozzles, first and second common channels connected to the individual channels, a first opening that is opened in the back surface and communicates with an end of the first common channel, and a second opening that is opened in the back surface and communicates with an end of the second common channel, and a filter member disposed on the back surface and having a filter that covers the first opening. The second opening is not covered with the filter, and an area of the first opening is larger than an area of the second opening.

Abstract: In a liquid ejection head, an ejection pressure is applied to a pressure chamber for liquid ejection from a nozzle. A descender extends in a first direction and includes a first end connected to the pressure chamber and a second end. A communication passage is connected to the second end, extends in a second direction crossing the first direction, and has a first dimension in the first direction. The nozzle is positioned at the communication passage such that a shortest distance between an outer periphery thereof and a center of the second end is greater than 0.5 times a second dimension of the second end in the second direction. When viewed in the first direction, the center of the second end and a center of a cross-section defined by the nozzle to be orthogonal to an extending direction of the nozzle intersect an axis of the communication passage.

Abstract: There is provide a liquid discharge head including: a supply manifold; a feedback manifold; and a plurality of individual flow channels having: a supply portion, a descender portion, and a feedback portion. The supply manifold has a plurality of supply ports, and the feedback manifold has a plurality of feedback ports. At least part of the supply manifold overlaps with the feedback manifold in the second direction. The plurality of pressure chambers have first pressure chambers forming a first pressure chamber array and second pressure chambers forming a second pressure chamber array. The first pressure chamber array is arranged at one side, of the supply manifold, in a third direction and the second pressure chamber array is arranged at the other side, of the supply manifold, in the third direction. The first pressure chamber array and the second pressure chamber array are connected to the supply manifold.

Abstract: There is provided a liquid discharge apparatus configured to discharge a liquid, including a channel member for the liquid. The channel member is formed to include: individual channels; a first and second manifold channels; and a bypass channel. Each of the individual channels and the bypass channel are all connected to the first manifold channel on only one of an upper and lower sides of a central portion between upper and lower surfaces of the first manifold channel, and connected to the second manifold channel on only one of upper and lower sides of a central portion between upper and lower surfaces of the second manifold channel A channel resistance of the bypass channel is smaller than that of the individual channels.

Abstract: There is provided a liquid discharge apparatus configured to discharge a liquid, including a channel member for the liquid. The channel member is formed to include: a pressure chamber configured to contain the liquid; a nozzle configured to discharge the liquid; a connection channel connecting the pressure chamber and the nozzle; and a discharge channel which is connected to the connection channel so as to discharge the liquid in the connection channel or connected to the pressure chamber so as to discharge the liquid in the pressure chamber. An intersection line between an orthogonal plane orthogonal to an extending direction of the discharge channel and an upper surface of the discharge channel defining an upper portion of the discharge channel has an arc-like shape protruding upwardly.