Patents by Inventor Shulamith Radin

Shulamith Radin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Xerogel films for the controlled release of pharmaceutically active molecules
    Patent number: 7850994
    Abstract: Xerogel films on substrates are provided containing pharmaceutically active compounds. Articles incorporating such films are robust, release active compounds at predictable rates and may provide such release for relatively long periods of time. Orthopedic and trauma uses are indicated along with generalized use in contact with body fluids or as biological implants. Methods for fabrication of such films and devices are provided.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: December 14, 2010
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin
  • Microspheroidal Controlled Release Of Biomolecules
    Publication number: 20070254038
    Abstract: Silica-based xerogel microspheres are provided containing pharmaceutically active compounds. These microspheres are robust, release active compounds at predictable rates and may provide such release for relatively long periods of time. Pharmaceutical compositions, methods for delivering medicaments and methods for treatment of disease states or conditions, inter alia, infection or pain, as well as methods for fabrication of such microspheres, are also provided.
    Type: Application
    Filed: April 25, 2007
    Publication date: November 1, 2007
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin, Tiffany Chen
  • Conditioning of bioactive glass surfaces in protein containing solutions
    Patent number: 6569466
    Abstract: Conditioning of the surface of silica-based glass or ceramic by differential immersion in a serum protein-containing solution, and the resultant microporous Ca-P surface layer having serum-protein like organic molecules, as defined herein intermingled throughout, is described.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: May 27, 2003
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin
  • Hollow bone mineral-like calcium phosphate particles
    Publication number: 20020172715
    Abstract: Hollow particles having a shell substantially composed of calcium-phosphate, methods for preparing the same, and methods of use are disclosed. The particles are obtained by differential immersion of silica-based, calcium and phosphate containing glass particles.
    Type: Application
    Filed: May 1, 2002
    Publication date: November 21, 2002
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Shulamith Radin, Paul Ducheyne, Sylvie Falaize, Portonovo S. Ayyaswamy
  • Hollow bone mineral-like calcium phosphate particles
    Patent number: 6416774
    Abstract: Hollow particles having a shell substantially composed of calcium-phosphate, methods for preparing the same, and methods of use are disclosed. The particles are obtained by differential immersion of silica-based, calcium and phosphate containing glass particles.
    Type: Grant
    Filed: May 9, 1996
    Date of Patent: July 9, 2002
    Assignee: The Trustees of the University of Pennsyvania
    Inventors: Shulamith Radin, Paul Ducheyne, Sylvie Falaize, Portonovo S. Ayyaswamy
  • Conditioning of bioactive glass surfaces in protein containing solutions
    Publication number: 20010014355
    Abstract: Conditioning of the surface of silica-based glass or ceramic by differential immersion in a serum protein-containing solution, and the resultant microporous Ca-P surface layer having serum-protein like organic molecules, as defined herein intermingled throughout, is described.
    Type: Application
    Filed: February 26, 2001
    Publication date: August 16, 2001
    Inventors: Paul Ducheyne, Shulamith Radin
  • Conditioning of bioactive glass surfaces in protein containing solutions
    Patent number: 6224913
    Abstract: Conditioning of the surface of silica-based glass or ceramic by differential immersion in a serum protein-containing solution, and the resultant microporous Ca—P surface layer having serum-protein like organic molecules, as defined herein intermingled throughout, is described.
    Type: Grant
    Filed: November 24, 1997
    Date of Patent: May 1, 2001
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin
  • Incorporation of biological molecules into bioactive glasses
    Patent number: 5874109
    Abstract: Carriers comprising silica-based glass providing for the controlled release of biologically active molecules, their methods of preparation, and methods of use are disclosed. The carriers are prepared using a sol-gel-derived process. Biologically active molecules are incorporated within the matrix of the glass during production.
    Type: Grant
    Filed: September 4, 1997
    Date of Patent: February 23, 1999
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin, Erick Manuel Santos
  • Incorporation of biologically active molecules into bioactive glasses
    Patent number: 5871777
    Abstract: Carriers comprising silica-based glass providing for the controlled release of biologically active molecules, their methods of preparation, and methods of use are disclosed. The carriers are prepared using a sol-gel-derived process. Biologically active molecules are incorporated within the matrix of the glass during production.
    Type: Grant
    Filed: May 2, 1997
    Date of Patent: February 16, 1999
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin, Erick Manuel Santos
  • Incorporation of biological molecules into bioactive glasses
    Patent number: 5861176
    Abstract: Carriers comprising silica-based glass providing for the controlled release of biologically active molecules, their methods of preparation, and methods of use are disclosed. The carriers are prepared using a sol-gel-derived process. Biologically active molecules are incorporated within the matrix of the glass during production.
    Type: Grant
    Filed: December 24, 1996
    Date of Patent: January 19, 1999
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin, Erick Manuel Santos
  • Incorporation of biological molecules into bioactive glasses
    Patent number: 5849331
    Abstract: Carriers comprising silica-based glass providing for the controlled release of biologically active molecules, their methods of preparation, and methods of use are disclosed. The carriers are prepared using a sol-gel-derived process. Biologically active molecules are incorporated within the matrix of the glass during production.
    Type: Grant
    Filed: September 3, 1997
    Date of Patent: December 15, 1998
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin, Erick Manuel Santos
  • Stabilization of sol-gel derived silica-based glass
    Patent number: 5830480
    Abstract: Methods for increasing the biocompatibility of silica-based glass having a concentration of silicon greater than 55%, compositions resulting therefrom, and methods for expeditious formation of calcium-phosphate films on sol-gel derived, silica-based bioactive glass are disclosed.
    Type: Grant
    Filed: May 9, 1996
    Date of Patent: November 3, 1998
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin, Sylvie Falaize, Erick Manuel Santos
  • Incorporation of biologically active molecules into bioactive glasses
    Patent number: 5817327
    Abstract: Carriers comprising silica-based glass providing for the controlled release of biologically active molecules, their methods of preparation, and methods of use are disclosed. The carriers are prepared using a sol-gel-derived process. Biologically active molecules are incorporated within the matrix of the glass during production.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: October 6, 1998
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin, Erick Manuel Santos
  • Incorporation of biologically active molecules into bioactive glasses
    Patent number: 5591453
    Abstract: Carriers comprising silica-based glass providing for the controlled release of biologically active molecules, their methods of preparation, and methods of use are disclosed. The carriers are prepared using a sol-gel-derived process. Biologically active molecules are incorporated within the matrix of the glass during production.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 7, 1997
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul Ducheyne, Shulamith Radin, Erick M. Santos