Patents by Inventor Shunji Mishiro

Shunji Mishiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100248210
    Abstract: The invention provides a method of detecting a drug-resistant strain of hepatitis B virus, including amplifying a hepatitis B virus nucleic acid in a sample solution by LAMP with a primer set to yield an amplification product, and hybridizing the amplification product with a probe containing a polynucleotide derived from a drug-resistant strain and/or a probe containing a polynucleotide derived from a drug-nonresistant strain, to detect a drug-resistant strain of hepatitis B virus.
    Type: Application
    Filed: March 23, 2009
    Publication date: September 30, 2010
    Inventors: Masayoshi Takahashi, Michie Hashimoto, Keiko Ito, Keiko Kizu, Shunji Mishiro, Kazuaki Takahashi, Kazunori Miyazaki, Koji Hashimoto, Nobuhiro Gemma
  • Patent number: 7659068
    Abstract: A carrier for gene detection as a means for prediction before treatment whether interferon therapy is valid or not for a patient, a method for detection of interferon therapy for an individual, an apparatus for gene detection, and a kit for detection of validity of interferon therapy.
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: February 9, 2010
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Minako Hijikata, Shunji Mishiro, Yasuhiko Oota, Koji Hashimoto
  • Publication number: 20080166710
    Abstract: The present invention provides methods for obtaining information regarding nucleic acid from an individual and nucleic acid associated with a disease of the individual, in particular when the disease is associated with a pathogenic microorganism present within the individual. The present invention also provide probe-immobilized substrates, such as probe-immobilized chips, for use in the methods. In particular, the present invention provides methods and probe-immobilized substrates for obtaining information regarding responsiveness to a treatment for a disease of an individual.
    Type: Application
    Filed: March 28, 2007
    Publication date: July 10, 2008
    Applicant: Kabushiki Kaisha Toshiba
    Inventors: Koji Hashimoto, Michie Hashimoto, Shunji Mishiro, Yasuhiko Oota
  • Publication number: 20070082353
    Abstract: There is provided a marker selection program for selecting a marker for use in genetic diagnosis. In the program, analysis is carried out by using at least two specimen databases which respectively store data of specimens belonging different populations. By carrying out analysis without integrating all specimen data into single population, information on a minority population can be surely reflected to a gene search. Since the characteristics of each population can be reflected, high-accuracy diagnosing functions can be obtained, providing a practical diagnosing system.
    Type: Application
    Filed: September 19, 2006
    Publication date: April 12, 2007
    Inventors: Yoshiko Hiraoka, Kazunori Miyazaki, Satoshi Itoh, Michie Hashimoto, Shunji Mishiro
  • Publication number: 20060246428
    Abstract: A polynucleotide probe that has a sequence of at least 8 nucleotides which can be hybridized with nucleotides from the hepatitis E virus JRA 1; a probe assay kit that includes the polynucleotide probe; and a chip on which the polynucleotide probe has been solid-phase fixed.
    Type: Application
    Filed: June 20, 2006
    Publication date: November 2, 2006
    Inventors: Kazuaki Takahashi, Shunji Mishiro, Yasuhiko Oota, Michie Hashimoto, Hiroshi Maekubo
  • Publication number: 20060228702
    Abstract: A polynucleotide probe that has a sequence of at least 8 nucleotides and is used for detecting at least one hepatitis E virus selected from JSN-FH, JKN-Sap, JMY-Haw, JAK-Sai, and JRA1; a probe assay kit that includes the polynucleotide probe; and a chip on which the polynucleotide probe has been solid-phase fixed.
    Type: Application
    Filed: June 20, 2006
    Publication date: October 12, 2006
    Inventors: Kazuaki Takahashi, Shunji Mishiro, Yasuhiko Oota, Michie Hashimoto, Hiroshi Maekubo
  • Patent number: 7101670
    Abstract: The present invention provides a polymorphic marker found in a region of the interferon receptor gene that can be used to assess the efficacy of interferon therapy. Thus, the present invention also relates to methods of assessing the efficacy of interferon therapy in an individual and means for accomplishing such a method.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: September 5, 2006
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Noriko Matsuyama, Masanobu Sugimoto, Michie Hashimoto, Shunji Mishiro
  • Publication number: 20050100909
    Abstract: A carrier for gene detection as a means for prediction before treatment whether interferon therapy is valid or not for a patient, a method for detection of interferon therapy for an individual, an apparatus for gene detection, and a kit for detection of validity of interferon therapy.
    Type: Application
    Filed: August 5, 2003
    Publication date: May 12, 2005
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Minako Hijikata, Shunji Mishiro, Yasuhiko Oota, Koji Hashimoto
  • Patent number: 6783935
    Abstract: The present invention provides polynucleotides having base sequences of sequence Nos. 1 to 4, as polynucleotides having polymorphism sites capable of being useful indicators for prediction of validity of interferon therapy.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: August 31, 2004
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Minako Hijikata, Shunji Mishiro, Yasuhiko Oota, Koji Hashimoto
  • Publication number: 20040101820
    Abstract: A polynucleotide probe including a sequence comprising at least eight nucleotides, the polynucleotide probe being used for detecting polynucleotide of hepatitis E virus, is characterized in that the sequence comprising at least eight nucleotides is hybridized with the polynucleotide of the hepatitis E virus, thereby, due to the hybridization, detects the hepatitis E virus.
    Type: Application
    Filed: September 19, 2002
    Publication date: May 27, 2004
    Inventors: Kazuaki Takahashi, Shunji Mishiro, Yasuhiko Oota, Michie Hashimoto, Hiroshi Maekubo
  • Publication number: 20040043379
    Abstract: The present invention provides methods for obtaining information regarding nucleic acid from an individual and nucleic acid associated with a disease of the individual, in particular when the disease is associated with a pathogenic microorganism present within the individual. The present invention also provide probe-immobilized substrates, such as probe-immobilized chips, for use in the methods. In particular, the present invention provides methods and probe-immobilized substrates for obtaining information regarding responsiveness to a treatment for a disease of an individual.
    Type: Application
    Filed: January 29, 2003
    Publication date: March 4, 2004
    Inventors: Koji Hashimoto, Michie Hashimoto, Shunji Mishiro, Yasuhiko Oota
  • Patent number: 6667155
    Abstract: A carrier for gene detection as a means for prediction before treatment whether interferon therapy is valid or not for a patient, a method for detection of interferon therapy for an individual, an apparatus for gene detection, and a kit for detection of validity of interferon therapy.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: December 23, 2003
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Minako Hijikata, Shunji Mishiro, Yasuhiko Oota, Koji Hashimoto
  • Publication number: 20030148336
    Abstract: The present invention provides a polymorphic marker found in a region of the interferon receptor gene that can be used to assess the efficacy of interferon therapy. Thus, the present invention also relates to methods of assessing the efficacy of interferon therapy in an individual and means for accomplishing such a method.
    Type: Application
    Filed: October 16, 2002
    Publication date: August 7, 2003
    Inventors: Noriko Matsuyama, Masanobu Sugimoto, Michie Hashimoto, Shunji Mishiro
  • Publication number: 20020127558
    Abstract: The present invention provides polynucleotides having base sequences of sequence Nos. 1 to 4, as polynucleotides having polymorphism sites capable of being useful indicators for prediction of validity of interferon therapy.
    Type: Application
    Filed: March 22, 2001
    Publication date: September 12, 2002
    Inventors: Minako Hijikata, Shunji Mishiro, Yasuhiko Oota, Koji Hashimoto
  • Publication number: 20020048758
    Abstract: A carrier for gene detection as a means for prediction before treatment whether interferon therapy is valid or not for a patient, a method for detection of interferon therapy for an individual, an apparatus for gene detection, and a kit for detection of validity of interferon therapy.
    Type: Application
    Filed: March 21, 2001
    Publication date: April 25, 2002
    Inventors: Minako Hijikata, Shunji Mishiro, Yasuhiko Oota, Koji Hashimoto
  • Patent number: 6103485
    Abstract: Novel nucleic acids, proteins, peptides, antigens, and antibodies related to non-A, non-B hepatitis, and non-A, non-B hepatitis diagnostic reagents using those materials.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: August 15, 2000
    Assignee: Immuno Japan Inc.
    Inventors: Shunji Mishiro, Tetsuo Nakamura
  • Patent number: 5766867
    Abstract: Novel nucleic acids, proteins, peptides, antigens, and antibodies related to non-A, non-B hepatitis, and non-A, non-B hepatitis diagnostic reagents using those materials.
    Type: Grant
    Filed: February 23, 1995
    Date of Patent: June 16, 1998
    Assignee: Immuno Japan Inc.
    Inventors: Shunji Mishiro, Tetsuo Nakamura
  • Patent number: 5176994
    Abstract: Non-A, Non-B Hepatitis Virus Genome RNA is disclosed along with cDNA and Virus Antigen Protein.
    Type: Grant
    Filed: May 15, 1991
    Date of Patent: January 5, 1993
    Assignee: Immuno Japan Inc.
    Inventors: Shunji Mishiro, Tetsuo Nakamura
  • Patent number: 5077193
    Abstract: Non-A, Non-B hepatitis virus genome RNA is disclosed along with cDNA and virus antigen protein.
    Type: Grant
    Filed: June 19, 1990
    Date of Patent: December 31, 1991
    Assignee: Immuno Japan Inc.
    Inventors: Shunji Mishiro, Tetsuo Nakamura