Patents by Inventor Shunsuke Izumi

Shunsuke Izumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12000304
    Abstract: A turbine blade includes: a blade body; and a plurality of cooling passages each extending inside the blade body along a blade height direction and are connected to each other via return portions disposed at an end portion in the blade height direction to form a serpentine passage. The cooling passages include: an upstream passage disposed on an upstream side in a flow of a cooling fluid among the plurality of cooling passages; a downstream passage disposed on a downstream side in the flow of the cooling fluid among the plurality of cooling passages; and at least one intermediate passage disposed between the upstream passage and the downstream passage among the plurality of cooling passages. The upstream passage is disposed closest to a leading edge in a chord direction of the blade body among the plurality of cooling passages formed inside the blade body and extending along the height direction.
    Type: Grant
    Filed: April 21, 2023
    Date of Patent: June 4, 2024
    Assignee: MITSUBISHI HEAVY INDUSTRIES, LTD.
    Inventors: Yusuke Izumi, Yasuo Miyahisa, Shunsuke Torii
  • Patent number: 11545350
    Abstract: One mode is a method for the structural analysis of an organic compound by MALDI mass spectrometry, including: a sample preparation process (S1) which includes preparing a sample by mixing a specimen containing an organic compound to be analyzed with a predetermined matrix at a mixture ratio within a range from 1:5 to 1:5000 in molar ratio; a mass spectrometry process (S3) which includes irradiating the prepared sample with a laser beam having a spot size equal to or smaller than 15 ?m to generate ions originating from a component of the specimen in the sample, and performing a mass spectrometric analysis of the generated ions; and an analyzing process (S4) which includes detecting, from a mass spectrum acquired in the mass spectrometry process, ions including product ions resulting from in-source decay, and estimating the structure of the organic compound to be analyzed based on information concerning the ions.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: January 3, 2023
    Assignees: SHIMADZU CORPORATION, HIROSHIMA UNIVERSITY
    Inventors: Koichi Tanaka, Takushi Yamamoto, Manaho Yamaguchi, Shunsuke Izumi
  • Publication number: 20210358733
    Abstract: One mode is a method for the structural analysis of an organic compound by MALDI mass spectrometry, including: a sample preparation process (S1) which includes preparing a sample by mixing a specimen containing an organic compound to be analyzed with a predetermined matrix at a mixture ratio within a range from 1:5 to 1:5000 in molar ratio; a mass spectrometry process (S3) which includes irradiating the prepared sample with a laser beam having a spot size equal to or smaller than 15 ?m to generate ions originating from a component of the specimen in the sample, and performing a mass spectrometric analysis of the generated ions; and an analyzing process (S4) which includes detecting, from a mass spectrum acquired in the mass spectrometry process, ions including product ions resulting from in-source decay, and estimating the structure of the organic compound to be analyzed based on information concerning the ions.
    Type: Application
    Filed: June 28, 2021
    Publication date: November 18, 2021
    Applicants: SHIMADZU CORPORATION, HIROSHIMA UNIVERSITY
    Inventors: Koichi TANAKA, Takushi YAMAMOTO, Manaho YAMAGUCHI, Shunsuke IZUMI
  • Patent number: 10626141
    Abstract: The present invention provides a method for specifically cleaving a C?-C bond of a peptide backbone and/or a side chain of a protein and a peptide, and a method for determining amino acid sequences of protein and peptide. A method for specifically cleaving a C?-C bond of a peptide backbone and/or a side chain bond of a protein or a peptide, comprising irradiating a protein or a peptide with laser light in the presence of at least one hydroxynitrobenzoic acid selected from the group consisting of 3-hydroxy-2-nitrobenzoic acid, 4-hydroxy-3-nitrobenzoic acid, 5-hydroxy-2-nitrobenzoic acid, 3-hydroxy-5-nitrobenzoic acid, and 4-hydroxy-2-nitrobenzoic acid. A method for determining an amino acid sequence of a protein or a peptide, comprising irradiating a protein or a peptide with laser light in the presence of the above specific hydroxynitrobenzoic acid to specifically cleave a C?-C bond of a peptide backbone and/or a side chain bond, and analyzing generated fragment ions by mass spectrometry.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: April 21, 2020
    Assignees: SHIMADZU CORPORATION, NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY
    Inventors: Shunsuke Izumi, Koichi Tanaka, Yuko Fukuyama
  • Publication number: 20180364549
    Abstract: Functionality corresponding to an imaging situation of an imaging apparatus is improved. The present technology includes an imaging apparatus attachment portion, to/from which an imaging apparatus is attachable/detachable; a control device attachment portion that holds a control apparatus capable of controlling the imaging apparatus; and a grip portion that is coupled to the imaging apparatus attachment portion and the control device attachment portion and is held by fingers. Accordingly, the grip portion can be held by fingers in the state where the imaging apparatus is attached to the imaging apparatus attachment portion and the control apparatus is held by the control device attachment portion. This makes it possible to improve the functionality corresponding to an imaging circumstance of the imaging apparatus.
    Type: Application
    Filed: November 14, 2016
    Publication date: December 20, 2018
    Inventors: MOKUYOH NAKANO, SHUNSUKE IZUMI, TAKAHIRO TSUGE
  • Publication number: 20180356711
    Abstract: To improve the convenience of handling. It includes a communication unit capable of wirelessly communicating with an imaging apparatus; a display control unit that displays information regarding the imaging apparatus on the basis of communication with the imaging apparatus; and an attachable/detachable portion that is engageable with a locking portion of an accessory and attachable/detachable to/from the locking portion of the accessory. Accordingly, since it can be wirelessly connected to the imaging apparatus and control can be performed on the imaging apparatus in a state where the control apparatus is locked to the accessory, it is possible to improve the convenience of handling.
    Type: Application
    Filed: November 14, 2016
    Publication date: December 13, 2018
    Inventors: Katsuyoshi Otsuka, Kouji Shimizu, Yuuji Sasaki, Keita Okuda, Mokuyoh Nakano, Shunsuke Izumi, Takayuki Houshiyama, Yoshihiro Aoyanagi, Tomotsugu Minamikawa, Takumi Suzuki, Takahiro Tsuge, Keiichi Iwasaki
  • Patent number: 9885725
    Abstract: The present invention provides a mass spectrometry method that can achieve analysis with high sensitivity using a matrix additive capable of improving ionization efficiency in mass spectrometry. A mass spectrometry method comprising the steps of: forming a mixed crystal for mass spectrometry on a target plate for mass spectrometry, the mixed crystal comprising a sample to be analyzed, a matrix, and a matrix additive selected from the group consisting of a 2,5-dihydroxybenzoate and a 3,5-dihydroxybenzoate that are represented by the following formula (I): where R represents an alkyl group having 4 to 14 carbon atoms; and irradiating the mixed crystal with laser to detect the sample to be analyzed.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: February 6, 2018
    Assignees: SHIMADZU CORPORATION, HIROSHIMA UNIVERSITY
    Inventors: Yuko Fukuyama, Shunsuke Izumi
  • Patent number: 9833828
    Abstract: A hot-press deep-drawing forming apparatus includes a punch that constitutes a lower die and a die that constitutes an upper die. The punch has an inner-face forming surface that forms the inner face of a product, and a bent corner against which a scrap section S of a workpiece W abuts. The die has an outer-face forming surface that forms the outer surface of the product. A blank holder and a pre-forming die that clamp the scrap section are caused to move, together with the die, until the clamped scrap section abuts the bent corner. The movement of the blank holder and the pre-forming die is stopped after the scrap section has abutted the bent corner.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: December 5, 2017
    Assignee: SUBARU CORPORATION
    Inventors: Takanori Ueda, Tomoyuki Horimoto, Shunsuke Izumi
  • Publication number: 20170327533
    Abstract: The present invention provides a method for specifically cleaving a C?-C bond of a peptide backbone and/or a side chain of a protein and a peptide, and a method for determining amino acid sequences of protein and peptide. A method for specifically cleaving a C?-C bond of a peptide backbone and/or a side chain bond of a protein or a peptide, comprising irradiating a protein or a peptide with laser light in the presence of at least one hydroxynitrobenzoic acid selected from the group consisting of 3-hydroxy-2-nitrobenzoic acid, 4-hydroxy-3-nitrobenzoic acid, 5-hydroxy-2-nitrobenzoic acid, 3-hydroxy-5-nitrobenzoic acid, and 4-hydroxy-2-nitrobenzoic acid. A method for determining an amino acid sequence of a protein or a peptide, comprising irradiating a protein or a peptide with laser light in the presence of the above specific hydroxynitrobenzoic acid to specifically cleave a C?-C bond of a peptide backbone and/or a side chain bond, and analyzing generated fragment ions by mass spectrometry.
    Type: Application
    Filed: May 12, 2017
    Publication date: November 16, 2017
    Inventors: Shunsuke Izumi, Koichi Tanaka, Yuko Fukuyama
  • Patent number: 9453846
    Abstract: The present invention provides a mass spectrometry method using a matrix that is capable of easily and efficiently improving ionization efficiency in mass spectrometry without modifying a molecule to be analyzed, and a matrix for mass spectrometry. A mass spectrometry method using, as a matrix, a 2,4,6-trihydroxyalkylphenone represented by the following general formula (I): where R is an alkyl group having 4 to 12 carbon atoms. The mass spectrometry method as described above, wherein an analysis object is a hydrophobic compound, particularly, a hydrophobic peptide.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: September 27, 2016
    Assignees: SHIMADZU CORPORATION, NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY
    Inventors: Yuko Fukuyama, Shunsuke Izumi
  • Publication number: 20160011205
    Abstract: The present invention provides amass spectrometry method using a matrix that is capable of easily and efficiently improving ionization efficiency in mass spectrometry without modifying a molecule to be analyzed, and a matrix for mass spectrometry. A mass spectrometry method using, as a matrix, a 2,4,6-trihydroxyalkylphenone represented by the following general formula (I): where R is an alkyl group having 4 to 12 carbon atoms. The mass spectrometry method as described above, wherein an analysis object is a hydrophobic compound, particularly, a hydrophobic peptide.
    Type: Application
    Filed: March 4, 2014
    Publication date: January 14, 2016
    Applicant: Shimadzu Corporation
    Inventors: Yuko Fukuyama, Shunsuke Izumi
  • Publication number: 20150276756
    Abstract: The present invention provides amass spectrometry method that can achieve analysis with high sensitivity using a matrix additive capable of improving ionization efficiency in mass spectrometry. Amass spectrometry method comprising the steps of: forming a mixed crystal for mass spectrometry on a target plate for mass spectrometry, the mixed crystal comprising a sample to be analyzed, a matrix, and a matrix additive selected from the group consisting of a 2,5-dihydroxybenzoate and a 3,5-dihydroxybenzoate that are represented by the following formula (I): where R represents an alkyl group having 4 to 14 carbon atoms; and irradiating the mixed crystal with laser to detect the sample to be analyzed.
    Type: Application
    Filed: September 24, 2014
    Publication date: October 1, 2015
    Inventors: Yuko Fukuyama, Shunsuke Izumi
  • Publication number: 20150266076
    Abstract: A hot-press deep-drawing forming apparatus includes a punch that constitutes a lower die and a die that constitutes an upper die. The punch has an inner-face forming surface that forms the inner face of a product, and a bent corner against which a scrap section S of a workpiece W abuts. The die has an outer-face forming surface that forms the outer surface of the product. A blank holder and a pre-forming die that clamp the scrap section are caused to move, together with the die, until the clamped scrap section abuts the bent corner. The movement of the blank holder and the pre-forming die is stopped after the scrap section has abutted the bent corner.
    Type: Application
    Filed: March 10, 2015
    Publication date: September 24, 2015
    Applicant: FUJI JUKOGYO KABUSHIKI KAISHA
    Inventors: Takanori UEDA, Tomoyuki HORIMOTO, Shunsuke IZUMI
  • Publication number: 20140084152
    Abstract: The present invention provides a novel compound that makes it possible to improve ionization efficiency of hydrophobic peptide. 5-alkoxy-2- or -3-hydroxybenzoic acid represented by the following formula (I): where R is an alkyl group having 6 to 10 carbon atoms and the substituted carboxyl group and hydroxyl group are ortho or meta to each other. A matrix additive for mass spectrometry, which is represented by the above formula (I). The above additive which is added to a matrix for mass spectrometry selected from the group consisting of ?-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, sinapic acid, and 1,5-diaminonaphthalene. The above additive which is used for mass spectrometry of a hydrophobic peptide.
    Type: Application
    Filed: November 15, 2013
    Publication date: March 27, 2014
    Applicants: HIROSHIMA UNIVERSITY, SHIMADZU CORPORATION
    Inventors: Yuko Fukuyama, Shunsuke Izumi
  • Publication number: 20130062570
    Abstract: The present invention provides a novel compound that makes it possible to improve ionization efficiency of hydrophobic peptide. 5-alkoxy-2- or -3-hydroxybenzoic acid represented by the following formula (I): where R is an alkyl group having 6 to 10 carbon atoms and the substituted carboxyl group and hydroxyl group are ortho or meta to each other. A matrix additive for mass spectrometry, which is represented by the above formula (I). The above additive which is added to a matrix for mass spectrometry selected from the group consisting of ?-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, sinapic acid, and 1,5-diaminonaphthalene. The above additive which is used for mass spectrometry of a hydrophobic peptide.
    Type: Application
    Filed: August 25, 2012
    Publication date: March 14, 2013
    Inventors: Yuko Fukuyama, Shunsuke Izumi
  • Publication number: 20070015333
    Abstract: A method of manufacturing a semiconductor device is disclosed that includes the treating the surface of a SiC semiconductor substrate prior to forming a gate oxide film on the SiC semiconductor substrate in order to etch the SiC semiconductor substrate by several nm to 0.1 ?m with hydrogen in a reaction furnace. The treating is conducted a reduced pressure in the furnace, at a temperature of 1500° C. or higher. The manufacturing method facilitates the removal of particles and oxide residues remaining on the trench inner wall after trench etching in the manufacturing process for manufacturing a SiC semiconductor device having a fine trench-type MOS gate structure.
    Type: Application
    Filed: June 13, 2006
    Publication date: January 18, 2007
    Applicant: Fuji Electric Holdings Co., Ltd.
    Inventors: Daisuke Kishimoto, Takeshi Tawara, Takashi Tsuji, Shunsuke Izumi
  • Publication number: 20060252243
    Abstract: An epitaxial film deposition system includes a reactor, a susceptor, a wafer heating unit, a reactant gas supply orifice, and an aperture for venting the reactant gas. The reactant gas is supplied to a reactor region between the susceptor and a graphite plate so as to circulate in layered flow in a direction along the reactor inner wall in the planar direction of a mounted SiC wafer. The temperature of the wafer is controlled by a high frequency coil and halogen lamps based on temperatures detected by a pyrometer. By circulating the reactant gas over the surface of the stationary wafer, it is possible to form, under various process conditions, an SiC epitaxial film having good film quality and good uniformity of film thickness, without providing any wafer rotation mechanism.
    Type: Application
    Filed: April 6, 2006
    Publication date: November 9, 2006
    Applicant: FUJI ELECTRIC HOLDINGS CO., LTD.
    Inventors: Daisuke Kishimoto, Takeshi Tawara, Shunsuke Izumi