Patents by Inventor Shunsuke Izumi
Shunsuke Izumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12000304Abstract: A turbine blade includes: a blade body; and a plurality of cooling passages each extending inside the blade body along a blade height direction and are connected to each other via return portions disposed at an end portion in the blade height direction to form a serpentine passage. The cooling passages include: an upstream passage disposed on an upstream side in a flow of a cooling fluid among the plurality of cooling passages; a downstream passage disposed on a downstream side in the flow of the cooling fluid among the plurality of cooling passages; and at least one intermediate passage disposed between the upstream passage and the downstream passage among the plurality of cooling passages. The upstream passage is disposed closest to a leading edge in a chord direction of the blade body among the plurality of cooling passages formed inside the blade body and extending along the height direction.Type: GrantFiled: April 21, 2023Date of Patent: June 4, 2024Assignee: MITSUBISHI HEAVY INDUSTRIES, LTD.Inventors: Yusuke Izumi, Yasuo Miyahisa, Shunsuke Torii
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Patent number: 11545350Abstract: One mode is a method for the structural analysis of an organic compound by MALDI mass spectrometry, including: a sample preparation process (S1) which includes preparing a sample by mixing a specimen containing an organic compound to be analyzed with a predetermined matrix at a mixture ratio within a range from 1:5 to 1:5000 in molar ratio; a mass spectrometry process (S3) which includes irradiating the prepared sample with a laser beam having a spot size equal to or smaller than 15 ?m to generate ions originating from a component of the specimen in the sample, and performing a mass spectrometric analysis of the generated ions; and an analyzing process (S4) which includes detecting, from a mass spectrum acquired in the mass spectrometry process, ions including product ions resulting from in-source decay, and estimating the structure of the organic compound to be analyzed based on information concerning the ions.Type: GrantFiled: June 28, 2021Date of Patent: January 3, 2023Assignees: SHIMADZU CORPORATION, HIROSHIMA UNIVERSITYInventors: Koichi Tanaka, Takushi Yamamoto, Manaho Yamaguchi, Shunsuke Izumi
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Publication number: 20210358733Abstract: One mode is a method for the structural analysis of an organic compound by MALDI mass spectrometry, including: a sample preparation process (S1) which includes preparing a sample by mixing a specimen containing an organic compound to be analyzed with a predetermined matrix at a mixture ratio within a range from 1:5 to 1:5000 in molar ratio; a mass spectrometry process (S3) which includes irradiating the prepared sample with a laser beam having a spot size equal to or smaller than 15 ?m to generate ions originating from a component of the specimen in the sample, and performing a mass spectrometric analysis of the generated ions; and an analyzing process (S4) which includes detecting, from a mass spectrum acquired in the mass spectrometry process, ions including product ions resulting from in-source decay, and estimating the structure of the organic compound to be analyzed based on information concerning the ions.Type: ApplicationFiled: June 28, 2021Publication date: November 18, 2021Applicants: SHIMADZU CORPORATION, HIROSHIMA UNIVERSITYInventors: Koichi TANAKA, Takushi YAMAMOTO, Manaho YAMAGUCHI, Shunsuke IZUMI
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Patent number: 10626141Abstract: The present invention provides a method for specifically cleaving a C?-C bond of a peptide backbone and/or a side chain of a protein and a peptide, and a method for determining amino acid sequences of protein and peptide. A method for specifically cleaving a C?-C bond of a peptide backbone and/or a side chain bond of a protein or a peptide, comprising irradiating a protein or a peptide with laser light in the presence of at least one hydroxynitrobenzoic acid selected from the group consisting of 3-hydroxy-2-nitrobenzoic acid, 4-hydroxy-3-nitrobenzoic acid, 5-hydroxy-2-nitrobenzoic acid, 3-hydroxy-5-nitrobenzoic acid, and 4-hydroxy-2-nitrobenzoic acid. A method for determining an amino acid sequence of a protein or a peptide, comprising irradiating a protein or a peptide with laser light in the presence of the above specific hydroxynitrobenzoic acid to specifically cleave a C?-C bond of a peptide backbone and/or a side chain bond, and analyzing generated fragment ions by mass spectrometry.Type: GrantFiled: May 12, 2017Date of Patent: April 21, 2020Assignees: SHIMADZU CORPORATION, NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITYInventors: Shunsuke Izumi, Koichi Tanaka, Yuko Fukuyama
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Publication number: 20180364549Abstract: Functionality corresponding to an imaging situation of an imaging apparatus is improved. The present technology includes an imaging apparatus attachment portion, to/from which an imaging apparatus is attachable/detachable; a control device attachment portion that holds a control apparatus capable of controlling the imaging apparatus; and a grip portion that is coupled to the imaging apparatus attachment portion and the control device attachment portion and is held by fingers. Accordingly, the grip portion can be held by fingers in the state where the imaging apparatus is attached to the imaging apparatus attachment portion and the control apparatus is held by the control device attachment portion. This makes it possible to improve the functionality corresponding to an imaging circumstance of the imaging apparatus.Type: ApplicationFiled: November 14, 2016Publication date: December 20, 2018Inventors: MOKUYOH NAKANO, SHUNSUKE IZUMI, TAKAHIRO TSUGE
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Publication number: 20180356711Abstract: To improve the convenience of handling. It includes a communication unit capable of wirelessly communicating with an imaging apparatus; a display control unit that displays information regarding the imaging apparatus on the basis of communication with the imaging apparatus; and an attachable/detachable portion that is engageable with a locking portion of an accessory and attachable/detachable to/from the locking portion of the accessory. Accordingly, since it can be wirelessly connected to the imaging apparatus and control can be performed on the imaging apparatus in a state where the control apparatus is locked to the accessory, it is possible to improve the convenience of handling.Type: ApplicationFiled: November 14, 2016Publication date: December 13, 2018Inventors: Katsuyoshi Otsuka, Kouji Shimizu, Yuuji Sasaki, Keita Okuda, Mokuyoh Nakano, Shunsuke Izumi, Takayuki Houshiyama, Yoshihiro Aoyanagi, Tomotsugu Minamikawa, Takumi Suzuki, Takahiro Tsuge, Keiichi Iwasaki
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Patent number: 9885725Abstract: The present invention provides a mass spectrometry method that can achieve analysis with high sensitivity using a matrix additive capable of improving ionization efficiency in mass spectrometry. A mass spectrometry method comprising the steps of: forming a mixed crystal for mass spectrometry on a target plate for mass spectrometry, the mixed crystal comprising a sample to be analyzed, a matrix, and a matrix additive selected from the group consisting of a 2,5-dihydroxybenzoate and a 3,5-dihydroxybenzoate that are represented by the following formula (I): where R represents an alkyl group having 4 to 14 carbon atoms; and irradiating the mixed crystal with laser to detect the sample to be analyzed.Type: GrantFiled: September 24, 2014Date of Patent: February 6, 2018Assignees: SHIMADZU CORPORATION, HIROSHIMA UNIVERSITYInventors: Yuko Fukuyama, Shunsuke Izumi
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Patent number: 9833828Abstract: A hot-press deep-drawing forming apparatus includes a punch that constitutes a lower die and a die that constitutes an upper die. The punch has an inner-face forming surface that forms the inner face of a product, and a bent corner against which a scrap section S of a workpiece W abuts. The die has an outer-face forming surface that forms the outer surface of the product. A blank holder and a pre-forming die that clamp the scrap section are caused to move, together with the die, until the clamped scrap section abuts the bent corner. The movement of the blank holder and the pre-forming die is stopped after the scrap section has abutted the bent corner.Type: GrantFiled: March 10, 2015Date of Patent: December 5, 2017Assignee: SUBARU CORPORATIONInventors: Takanori Ueda, Tomoyuki Horimoto, Shunsuke Izumi
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Publication number: 20170327533Abstract: The present invention provides a method for specifically cleaving a C?-C bond of a peptide backbone and/or a side chain of a protein and a peptide, and a method for determining amino acid sequences of protein and peptide. A method for specifically cleaving a C?-C bond of a peptide backbone and/or a side chain bond of a protein or a peptide, comprising irradiating a protein or a peptide with laser light in the presence of at least one hydroxynitrobenzoic acid selected from the group consisting of 3-hydroxy-2-nitrobenzoic acid, 4-hydroxy-3-nitrobenzoic acid, 5-hydroxy-2-nitrobenzoic acid, 3-hydroxy-5-nitrobenzoic acid, and 4-hydroxy-2-nitrobenzoic acid. A method for determining an amino acid sequence of a protein or a peptide, comprising irradiating a protein or a peptide with laser light in the presence of the above specific hydroxynitrobenzoic acid to specifically cleave a C?-C bond of a peptide backbone and/or a side chain bond, and analyzing generated fragment ions by mass spectrometry.Type: ApplicationFiled: May 12, 2017Publication date: November 16, 2017Inventors: Shunsuke Izumi, Koichi Tanaka, Yuko Fukuyama
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Patent number: 9453846Abstract: The present invention provides a mass spectrometry method using a matrix that is capable of easily and efficiently improving ionization efficiency in mass spectrometry without modifying a molecule to be analyzed, and a matrix for mass spectrometry. A mass spectrometry method using, as a matrix, a 2,4,6-trihydroxyalkylphenone represented by the following general formula (I): where R is an alkyl group having 4 to 12 carbon atoms. The mass spectrometry method as described above, wherein an analysis object is a hydrophobic compound, particularly, a hydrophobic peptide.Type: GrantFiled: March 4, 2014Date of Patent: September 27, 2016Assignees: SHIMADZU CORPORATION, NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITYInventors: Yuko Fukuyama, Shunsuke Izumi
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Publication number: 20160011205Abstract: The present invention provides amass spectrometry method using a matrix that is capable of easily and efficiently improving ionization efficiency in mass spectrometry without modifying a molecule to be analyzed, and a matrix for mass spectrometry. A mass spectrometry method using, as a matrix, a 2,4,6-trihydroxyalkylphenone represented by the following general formula (I): where R is an alkyl group having 4 to 12 carbon atoms. The mass spectrometry method as described above, wherein an analysis object is a hydrophobic compound, particularly, a hydrophobic peptide.Type: ApplicationFiled: March 4, 2014Publication date: January 14, 2016Applicant: Shimadzu CorporationInventors: Yuko Fukuyama, Shunsuke Izumi
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Publication number: 20150276756Abstract: The present invention provides amass spectrometry method that can achieve analysis with high sensitivity using a matrix additive capable of improving ionization efficiency in mass spectrometry. Amass spectrometry method comprising the steps of: forming a mixed crystal for mass spectrometry on a target plate for mass spectrometry, the mixed crystal comprising a sample to be analyzed, a matrix, and a matrix additive selected from the group consisting of a 2,5-dihydroxybenzoate and a 3,5-dihydroxybenzoate that are represented by the following formula (I): where R represents an alkyl group having 4 to 14 carbon atoms; and irradiating the mixed crystal with laser to detect the sample to be analyzed.Type: ApplicationFiled: September 24, 2014Publication date: October 1, 2015Inventors: Yuko Fukuyama, Shunsuke Izumi
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Publication number: 20150266076Abstract: A hot-press deep-drawing forming apparatus includes a punch that constitutes a lower die and a die that constitutes an upper die. The punch has an inner-face forming surface that forms the inner face of a product, and a bent corner against which a scrap section S of a workpiece W abuts. The die has an outer-face forming surface that forms the outer surface of the product. A blank holder and a pre-forming die that clamp the scrap section are caused to move, together with the die, until the clamped scrap section abuts the bent corner. The movement of the blank holder and the pre-forming die is stopped after the scrap section has abutted the bent corner.Type: ApplicationFiled: March 10, 2015Publication date: September 24, 2015Applicant: FUJI JUKOGYO KABUSHIKI KAISHAInventors: Takanori UEDA, Tomoyuki HORIMOTO, Shunsuke IZUMI
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Publication number: 20140084152Abstract: The present invention provides a novel compound that makes it possible to improve ionization efficiency of hydrophobic peptide. 5-alkoxy-2- or -3-hydroxybenzoic acid represented by the following formula (I): where R is an alkyl group having 6 to 10 carbon atoms and the substituted carboxyl group and hydroxyl group are ortho or meta to each other. A matrix additive for mass spectrometry, which is represented by the above formula (I). The above additive which is added to a matrix for mass spectrometry selected from the group consisting of ?-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, sinapic acid, and 1,5-diaminonaphthalene. The above additive which is used for mass spectrometry of a hydrophobic peptide.Type: ApplicationFiled: November 15, 2013Publication date: March 27, 2014Applicants: HIROSHIMA UNIVERSITY, SHIMADZU CORPORATIONInventors: Yuko Fukuyama, Shunsuke Izumi
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Publication number: 20130062570Abstract: The present invention provides a novel compound that makes it possible to improve ionization efficiency of hydrophobic peptide. 5-alkoxy-2- or -3-hydroxybenzoic acid represented by the following formula (I): where R is an alkyl group having 6 to 10 carbon atoms and the substituted carboxyl group and hydroxyl group are ortho or meta to each other. A matrix additive for mass spectrometry, which is represented by the above formula (I). The above additive which is added to a matrix for mass spectrometry selected from the group consisting of ?-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, sinapic acid, and 1,5-diaminonaphthalene. The above additive which is used for mass spectrometry of a hydrophobic peptide.Type: ApplicationFiled: August 25, 2012Publication date: March 14, 2013Inventors: Yuko Fukuyama, Shunsuke Izumi
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Publication number: 20070015333Abstract: A method of manufacturing a semiconductor device is disclosed that includes the treating the surface of a SiC semiconductor substrate prior to forming a gate oxide film on the SiC semiconductor substrate in order to etch the SiC semiconductor substrate by several nm to 0.1 ?m with hydrogen in a reaction furnace. The treating is conducted a reduced pressure in the furnace, at a temperature of 1500° C. or higher. The manufacturing method facilitates the removal of particles and oxide residues remaining on the trench inner wall after trench etching in the manufacturing process for manufacturing a SiC semiconductor device having a fine trench-type MOS gate structure.Type: ApplicationFiled: June 13, 2006Publication date: January 18, 2007Applicant: Fuji Electric Holdings Co., Ltd.Inventors: Daisuke Kishimoto, Takeshi Tawara, Takashi Tsuji, Shunsuke Izumi
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Publication number: 20060252243Abstract: An epitaxial film deposition system includes a reactor, a susceptor, a wafer heating unit, a reactant gas supply orifice, and an aperture for venting the reactant gas. The reactant gas is supplied to a reactor region between the susceptor and a graphite plate so as to circulate in layered flow in a direction along the reactor inner wall in the planar direction of a mounted SiC wafer. The temperature of the wafer is controlled by a high frequency coil and halogen lamps based on temperatures detected by a pyrometer. By circulating the reactant gas over the surface of the stationary wafer, it is possible to form, under various process conditions, an SiC epitaxial film having good film quality and good uniformity of film thickness, without providing any wafer rotation mechanism.Type: ApplicationFiled: April 6, 2006Publication date: November 9, 2006Applicant: FUJI ELECTRIC HOLDINGS CO., LTD.Inventors: Daisuke Kishimoto, Takeshi Tawara, Shunsuke Izumi