Patents by Inventor Shunsuke Kageyama
Shunsuke Kageyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10183022Abstract: Provided is a pharmaceutical composition for treating ulcerative colitis, comprising a compound represented by a formula (1) or a pharmaceutically acceptable salt thereof, wherein the compound or the pharmaceutically acceptable salt is administered in an amount of 600 mg or more per day to an ulcerative colitis patient.Type: GrantFiled: March 28, 2017Date of Patent: January 22, 2019Assignee: EA Pharma Co., Ltd.Inventors: Shunsuke Kageyama, Yoshiki Goda, Toshihiko Sugiura
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Publication number: 20170196870Abstract: Provided is a pharmaceutical composition for treating ulcerative colitis, comprising a compound represented by a formula (1) or a pharmaceutically acceptable salt thereof, wherein the compound or the pharmaceutically acceptable salt is administered in an amount of 600 mg or more per day to an ulcerative colitis patient.Type: ApplicationFiled: March 28, 2017Publication date: July 13, 2017Applicant: EA Pharma Co., Ltd.Inventors: Shunsuke KAGEYAMA, Yoshiki GODA, Toshihiko SUGIURA
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Patent number: 9533985Abstract: Sulfonamide compounds of a specific chemical structure in which a sulfonamide group having, as a substituent, a phenyl group or a heterocyclic group having a hetero atom(s) as a constituent element(s) is present at its terminal, and pharmaceutically acceptable salts thereof. These compounds are novel compounds having excellent ?4 integrin-inhibitory action.Type: GrantFiled: April 24, 2013Date of Patent: January 3, 2017Assignee: EA Pharma Co., Ltd.Inventors: Hirokazu Ueno, Takashi Yamamoto, Ryuta Takashita, Ryohei Yokoyama, Toshihiko Sugiura, Shunsuke Kageyama, Ayatoshi Ando, Hiroyuki Eda, Agung Eviryanti, Tomoko Miyazawa, Aya Kirihara, Itsuya Tanabe, Tarou Nakamura, Misato Noguchi, Manami Shuto, Masayuki Sugiki, Mizuki Dohi
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Publication number: 20150051395Abstract: Provided are sulfonamide derivatives of a specific chemical structure in which a sulfonamide group having, as a substituent, a phenyl group or a heterocyclic group having a hetero atom(s) as a constituent element(s) is present at its terminal, and pharmaceutically acceptable salts thereof. These compounds are novel compounds having excellent ?4 integrin-inhibitory action.Type: ApplicationFiled: April 24, 2013Publication date: February 19, 2015Applicant: AJINOMOTO CO., LTD.Inventors: Hirokazu Ueno, Takashi Yamamoto, Ryuta Takashita, Ryohei Yokoyama, Toshihiko Sugiura, Shunsuke Kageyama, Ayatoshi Ando, Hiroyuki Eda, Agung Eviryanti, Tomoko Miyazawa, Aya Kirihara, Itsuya Tanabe, Tarou Nakamura, Misato Noguchi, Manami Shuto, Masayuki Sugiki, Mizuki Dohi
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Publication number: 20130017548Abstract: The present invention relates to a novel method for screening for a therapeutic or prophylactic agent for an inflammatory disease. More particularly, the present invention relates to a method for screening for a therapeutic or prophylactic agent for an inflammatory disease by selecting a substance having an inhibitory activity specific to PIKfyve by using the presence or absence of the inhibitory activity as an indicator.Type: ApplicationFiled: June 27, 2012Publication date: January 17, 2013Applicant: AJINOMOTO, INC.Inventors: Sen Takeshita, Takashi Yamamoto, Ayatoshi Andou, Tomohisa Okutsu, Agung Eviryanti, Naoyuki Fukuchi, Shunsuke Kageyama
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Publication number: 20120323002Abstract: By searching various compounds having an inhibiting activity against IL-12/IL-23 production, the present invention provides a pharmaceutical composition or a therapeutic or preventive agent for diseases related to IL-12/IL-23 excessive production each of which comprises the compound(s) of the present invention. More specifically, the present invention provides an imidazopyridazine compound having an inhibiting activity against IL-12/IL-23 production or pharmaceutically acceptable salts thereof; and a useful pharmaceutical composition or a useful therapeutic or preventive agent for diseases related to IL-12/IL-23 excessive production each of which comprises said compound or pharmaceutically acceptable salts thereof.Type: ApplicationFiled: June 25, 2012Publication date: December 20, 2012Applicant: AJINOMOTO CO., INC.Inventors: Takashi YAMAMOTO, Ayatoshi ANDO, Nobuhiko HAYAKAWA, Masatsugu NOGUCHI, Hikaru NISHIO, Agung EVIRYANTI, Ryohei YOKOYAMA, Shunsuke KAGEYAMA, Kanna KURIBAYASHI
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Patent number: 8314098Abstract: The present invention has searched for a variety of compounds which show IL-12/IL-23 production-inhibitory activities and herein provides a pharmaceutical composition and an agent for preventing or treating IL-12/IL-23 excess production-related diseases, which comprise the compound.Type: GrantFiled: June 27, 2011Date of Patent: November 20, 2012Assignee: Ajinomoto Co., Inc.Inventors: Takashi Yamamoto, Ayatoshi Andou, Nobuhiko Hayakawa, Masatsugu Noguchi, Kanna Kuribayashi, Agung Eviryanti, Ryohei Yokoyama, Shunsuke Fukuda, Toshihiko Sugiura, Shunsuke Kageyama, Yoichiro Shima, Misato Noguchi
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Patent number: 8309561Abstract: Specific phenylalanine derivatives and analogues thereof have an antagonistic activity to ?4 integrin. They are used as therapeutic agents for various diseases concerning ?4 integrin.Type: GrantFiled: December 21, 2007Date of Patent: November 13, 2012Assignee: Ajinomoto Co., Inc.Inventors: Kazuyuki Sagi, Tatsuya Okuzumi, Tatsuhiro Yamada, Shunsuke Kageyama, Yoichiro Shima, Tadakiyo Nakagawa, Munetaka Tokumasu, Masayuki Sugiki, Hajime Ito, Itsuya Tanabe, Tamotsu Suzuki, Akira Nakayama, Kazuyuki Ubukata, Kenji Shinkai, Yasuhiro Tanaka, Misato Noguchi, Ayatoshi Andou, Yoriko Yamamoto, Noriyasu Kataoka, Koichi Fujita
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Publication number: 20110294781Abstract: The present invention has searched for a variety of compounds which show IL-12/IL-23 production-inhibitory activities and herein provides a pharmaceutical composition and an agent for preventing or treating IL-12/IL-23 excess production-related diseases, which comprise the compound.Type: ApplicationFiled: June 27, 2011Publication date: December 1, 2011Applicant: AJINOMOTO CO., INC.Inventors: Takashi YAMAMOTO, Ayatoshi Andou, Nobuhiko Hayakawa, Masatsugu Noguchi, Kanna Kuribayashi, Agung Eviryanti, Ryohei Yokoyama, Shunsuke Fukuda, Toshihiko Sugiura, Shunsuke Kageyama, Yoichiro Shima, Misato Noguchi
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Publication number: 20080108634Abstract: Specific phenylalanine derivatives and analogues thereof have an antagonistic activity to ?4 integrin. They are used as therapeutic agents for various diseases concerning ?4 integrin.Type: ApplicationFiled: December 21, 2007Publication date: May 8, 2008Applicant: Ajinomoto Co., Inc.Inventors: Kazuyuki SAGI, Tatsuya Okuzumi, Tatsuhiro Yamada, Shunsuke Kageyama, Yoichiro Shima, Tadakiyo Nakagawa, Munetaka Tokumasu, Masayuki Sugiki, Hajime Ito, Itsuya Tanabe, Tamotsu Suzuki, Akira Nakayama, Kazuyuki Ubukata, Kenji Shinkai, Yasuhiro Tanaka, Misato Noguchi, Ayatoshi Andou, Yoriko Yamamoto, Noriyasu Kataoka, Koichi Fujita
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Patent number: 7345049Abstract: Specific phenylalanine derivatives and analogues thereof have an antagonistic activity to ?4 integrin. They are used as therapeutic agents for various diseases concerning ?4 integrin.Type: GrantFiled: December 22, 2004Date of Patent: March 18, 2008Assignee: Ajinomoto Co., Inc.Inventors: Kazuyuki Sagi, Tatsuya Okuzumi, Tatsuhiro Yamada, Shunsuke Kageyama, Yoichiro Shima, Tadakiyo Nakagawa, Munetaka Tokumasu, Masayuki Sugiki, Hajime Ito, Itsuya Tanabe, Tamotsu Suzuki, Akira Nakayama, Kazuyuki Ubukata, Kenji Shinkai, Yasuhiro Tanaka, Misato Noguchi, Ayatoshi Andou, Yoriko Yamamoto, Noriyasu Kataoka, Koichi Fujita
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Patent number: 7270972Abstract: It is provided a method for producing a subunit peptide originating from an oligomeric protein having disulfide bonds within a subunit and between subunits. The method comprises producing a subunit originating from an oligomeric protein having disulfide bonds within a subunit and between subunits by the following steps: (a) a step of refolding the subunit by denaturing the oligomeric protein or its subunit in a solution with a protein-denaturing agent and removing the denaturing agent from the solution in the presence of polyoxyalkyl polyether having a functional group that reacts with a thiol group; and (b) a step of isolating the subunit bonded to the polyoxyalkyl polyether from the solution.Type: GrantFiled: March 31, 2000Date of Patent: September 18, 2007Assignee: Ajinomoto Co., Inc.Inventors: Naoyuki Fukuchi, Shunsuke Kageyama, Morikazu Kito, Takashi Kayahara, Hiroshi Yamamoto
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Publication number: 20050222141Abstract: Specific phenylalanine derivatives and analogues thereof have an antagonistic activity to ?4 integrin. They are used as therapeutic agents for various diseases concerning ?4 integrin.Type: ApplicationFiled: December 22, 2004Publication date: October 6, 2005Applicant: Ajinomoto Co., Inc.Inventors: Kazuyuki Sagi, Tatsuya Okuzumi, Tatsuhiro Yamada, Shunsuke Kageyama, Yoichiro Shima, Tadakiyo Nakagawa, Munetaka Tokumasu, Masayuki Sugiki, Hajime Ito, Itsuya Tanabe, Tamotsu Suzuki, Akira Nakayama, Kazuyuki Ubukata, Kenji Shinkai, Yasuhiro Tanaka, Misato Noguchi, Ayatoshi Andou, Yoriko Yamamoto, Noriyasu Kataoka, Koichi Fujita
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Publication number: 20050136056Abstract: The present invention provides a drug for the treatment of thrombocytopenia caused by hepatic failure, preferably a drug with few adverse drug reactions. A substance that inhibits binding between glycoprotein Ib (GPIb) and von Willebrand factor (vWF), for example, anti-GPIb antibody or anti-vWF antibody that inhibits binding between GPIb and vWF is an active ingredient of the drug for the treatment of thrombocytopenia.Type: ApplicationFiled: January 28, 2005Publication date: June 23, 2005Inventors: Shunsuke Kageyama, Ken Hirose, Hiroshi Yamamoto, Makoto Shiozaki, Junko Matsushita