Patents by Inventor Shuuichi Wakabayashi

Shuuichi Wakabayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic guanidine derivatives, anti-ulceratives and method of manufacturing the same
    Patent number: 5240944
    Abstract: Derivatives of cyclic guanidine are disclosed, which are represented by the following formula:A--S--Rwherein A is ##STR1## R.sub.1 represent a lower alkyl or substituted phenyl or unsubstituted phenyl group; R.sub.2 is a lower alkyl; R.sub.3 is H or a lower alkyl; R is lower alkyl, alkenyl, alkynyl, alkanoyl, alkenoyl, dialkylaminoalkyl, cyanoalkyl, alkoxycarbonylalkyl, carboxylalkenyl, alkoxycarbonyl, alkoxyalkylcarbonyl, dialkylaminocarbonyl, dialkylaminothiocarbonyl, phenoxyalkylcarbonyl, piperidinoalkyl, pyridine carbonyl, substituted or unsubstituted benzoyl, or substituted or unsubstituted benzyl group. The compounds of the present invention are useful as anti-ulcerative agents.
    Type: Grant
    Filed: March 7, 1991
    Date of Patent: August 31, 1993
    Assignee: Kotobuki Seiyaku Co. Ltd.
    Inventors: Tsuyoshi Tomiyama, Akira Tomiyama, Tadashi Shirai, Shuuichi Wakabayashi, Tomoyuki Kawai, Naoto Ueyama, Motoharu Sonegawa
  • Azulene derivatives as thromboxane A.sub.2 and prostaglandin endoperoxide receptor antagonist
    Patent number: 5081152
    Abstract: A series of new azulene analogues are disclosed, which are represented by the following formula: ##STR1## wherein: R.sub.1 is --COOH, --COOR.sub.4 (R.sub.4 represents a lower alkyl), --CH.dbd.CH--COOH, --CH.sub.2 --COOH or --SO.sub.3 H;R.sub.2 is a hydrogen atom or lower-alkyl group;R.sub.3 is a hydrogen atom, a lower alkyl or benzyl group;A is --SO.sub.2 --, ##STR2## (R.sub.5 represents a lower alkyl); B is a phenyl, a lower alkylphenyl, a lower alkoxyphenyl, nitrophenyl, trifluoroalkylphenyl, mono-or di-halogenated-phenyl, naphthyl or tetrahydroaphthyl group;Y is an alkylene or alkenylene group.The compounds of the present invention are useful as thromboxane A.sub.2 and prostagrandin endoperoxide receptor antagonists.
    Type: Grant
    Filed: June 26, 1990
    Date of Patent: January 14, 1992
    Assignee: Kotobuki Seiyaku Co., Ltd.
    Inventors: Tsuyoshi Tomiyama, Akira Tomiyama, Masayuki Yokota, Shuuichi Wakabayashi, Hiromi Hayashi, Rei Koyama, Masafumi Yasunami
  • Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same
    Patent number: 5008282
    Abstract: Derivatives of cyclic guanidine are disclosed, which are represented by the following formula:A--S--Rwherein A is ##STR1## R.sub.1 represent a lower alkyl or substituted phenyl or unsubstituted phenyl group; R.sub.2 is a lower alkyl; R.sub.3 is H or a lower alkyl; R is lower alkyl, alkenyl, alkynyl, alkanoyl, alkenoyl, dialkylaminoalkyl, cyanoalkyl, alkoxycarbonylalkyl, carboxylalkenyl, alkoxycarbonyl, alkoxyalkylcarbonyl, dialkylaminocarbonyl, dialkylaminothiocarbonyl, phenoxyalkylcarbonyl, piperidinoalkyl, pyridine carbonyl, substituted or unsubstituted benzoyl, or substituted or unsubstituted benzyl group.The compounds of the present invention are useful as anti-ulcerative agents.
    Type: Grant
    Filed: December 13, 1989
    Date of Patent: April 16, 1991
    Assignee: Kotobuki Seiyaku Co. Ltd.
    Inventors: Tsuyoshi Tomiyama, Akira Tomiyama, Tadashi Shirai, Shuuichi Wakabayashi, Tomoyuki Kawai, Naoto Ueyama, Motoharu Sonegawa