Patents by Inventor SHUXIA ZHOU

SHUXIA ZHOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR FREEZING AND THAWING MAMMALIAN CELLS
    Publication number: 20240050566
    Abstract: The present disclosure provides, among other things, a method of cryopreserving and thawing cells that results in the thawed cells having high cellular viability and functionality post-thawing. In some embodiments, a large-scale method of cryopreserving cells is provided, the method comprising: (a) contacting the cells with a cryopreservation medium; (b) cooling the cells to ?80° C. at a controlled rate to minimize latent heat of fusion; and (c) storing the cells in liquid nitrogen vapor phase, thereby cryopreserving the immune cells.
    Type: Application
    Filed: July 28, 2023
    Publication date: February 15, 2024
    Inventors: Shuxia ZHOU, Lan Cao, Dayong Gao, Qiong Xue, Jiusong Sun, Huang Zhu
  • Immunoassay for SARS-CoV-2 neutralizing antibodies and materials therefor
    Patent number: 11740240
    Abstract: The present invention relates to the development of novel immunoassays for the detection of neutralizing antibodies and/or high avidity neutralizing antibodies to SARS-CoV-2 spike protein variants or fragments thereof and, optionally, one or more cytokine in patient samples. Novel multiplex and singleplex immunoassays for the detection of neutralizing antibodies and/or high avidity neutralizing antibodies to SARS-CoV-2 spike protein variants or fragments thereof and, optionally, one or more cytokine in patient samples are also provided.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: August 29, 2023
    Assignee: BIO-RAD LABORATORIES, INC.
    Inventors: Qian Gao, Ravi Kaul, Shuxia Zhou, Roger P. Walker
  • IMMUNOASSAY FOR SARS-COV-2 AND MATERIALS THEREFOR
    Publication number: 20220326240
    Abstract: The present disclosure relates to the development of novel immunoassays for the detection of SARS-CoV-2 or secreted spike protein (or fragments thereof) in saliva, nasal mucosal sample, throat samples, or nasopharyngeal samples.
    Type: Application
    Filed: April 8, 2022
    Publication date: October 13, 2022
    Inventors: RAVI KAUL, SHUXIA ZHOU, ROGER P. WALKER
  • IMMUNOASSAY FOR SARS-COV-2 NEUTRALIZING ANTIBODIES AND MATERIALS THEREFOR
    Publication number: 20220018838
    Abstract: The present invention relates to the development of novel immunoassays for the detection of neutralizing antibodies and/or high avidity neutralizing antibodies to SARS-CoV-2 spike protein variants or fragments thereof and, optionally, one or more cytokine in patient samples. Novel multiplex and singleplex immunoassays for the detection of neutralizing antibodies and/or high avidity neutralizing antibodies to SARS-CoV-2 spike protein variants or fragments thereof and, optionally, one or more cytokine in patient samples are also provided.
    Type: Application
    Filed: July 19, 2021
    Publication date: January 20, 2022
    Inventors: QIAN GAO, RAVI KAUL, SHUXIA ZHOU, ROGER P. WALKER