Patents by Inventor Shuyuan Yao

Shuyuan Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted integration into stem cells
    Patent number: 9834787
    Abstract: Disclosed herein are methods and compositions for targeted integration of sequences of interest such as lineage-specific or cell fate reporter constructs or protein encoding sequences into stem cells.
    Type: Grant
    Filed: April 8, 2010
    Date of Patent: December 5, 2017
    Assignee: Sangamo Therapeutics, Inc.
    Inventors: Philip D. Gregory, Dirk Hockemeyer, Michael C. Holmes, Rudolf Jaenisch, Frank Soldner, Fyodor Urnov, Shuyuan Yao
  • Methods and compositions for targeted integration
    Patent number: 8936936
    Abstract: Disclosed herein are methods and compositions for targeted integration of one or more copies of a sequence of interest using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain and integrase defective lentiviral donor constructs.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: January 20, 2015
    Assignees: Sangamo BioSciences, Inc., Ospedale San Raffaele S.R.L.
    Inventors: Michael C. Holmes, Shuyuan Yao, Luigi Naldini, Angelo Leone Lombardo
  • Targeted integration into stem cells
    Publication number: 20110027235
    Abstract: Disclosed herein are methods and compositions for targeted integration of sequences of interest such as lineage-specific or cell fate reporter constructs or protein encoding sequences into stem cells.
    Type: Application
    Filed: April 8, 2010
    Publication date: February 3, 2011
    Inventors: Philip D. Gregory, Dirk Hockemeyer, Michael C. Holmes, Rudolf Jaenisch, Frank Soldner, Fyodor Urnov, Shuyuan Yao
  • Methods and compositions for targeted integration
    Publication number: 20090117617
    Abstract: Disclosed herein are methods and compositions for targeted integration of one or more copies of a sequence of interest using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain and integrase defective lentiviral donor constructs.
    Type: Application
    Filed: October 23, 2008
    Publication date: May 7, 2009
    Inventors: Michael C. Holmes, Shuyuan Yao