Patents by Inventor Shyama HERATH

Shyama HERATH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF QPCTL AND QPCT
    Publication number: 20240101544
    Abstract: Provided herein are compounds of formula (I) and formula (II) that are inhibitors of QPCTL and QPCT: Also provided are pharmaceutical compositions comprising the compounds, and methods for using the compounds for the treatment of disease.
    Type: Application
    Filed: July 20, 2023
    Publication date: March 28, 2024
    Inventors: James M. Veal, Jeffrey A. Stafford, Donald S. Karanewsky, Shyama Herath
  • Substituted imidazo[1,2-a]quinazolines and imidazo [1,2-a]pyrido[4,3-e]pyrimidines as inhibitors of PARG
    Patent number: 11939335
    Abstract: Provided herein are inhibitors of PARG, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the PARG inhibitory compounds for the treatment of disease.
    Type: Grant
    Filed: May 19, 2023
    Date of Patent: March 26, 2024
    Assignee: 858 THERAPEUTICS, INC.
    Inventors: James M. Veal, Jeffrey A. Stafford, Donald S. Karanewsky, Shyama Herath
  • INHIBITORS OF PARG
    Publication number: 20230374022
    Abstract: Provided herein are inhibitors of PARG, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the PARG inhibitory compounds for the treatment of disease.
    Type: Application
    Filed: May 19, 2023
    Publication date: November 23, 2023
    Inventors: James M. VEAL, Jeffrey A. STAFFORD, Donald S. KARANEWSKY, Shyama HERATH
  • 15-PGDH INHIBITORS
    Publication number: 20220073494
    Abstract: A compound having one of formula (1), formula (2), formula (3) and formula (4) or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: January 29, 2020
    Publication date: March 10, 2022
    Inventors: Shyama HERATH, Mariangela URBANO, Eun-Kyong KIM, Chixu CHEN, Qiang LI, Julia AYERS, Kaikoo NAKAMURA, Xiuwen ZHU, Hugh ROSEN, Jonathan S. ROSENBLUM, Melissa C. ZHANG, Yongsheng LIU, Masahiro UENO