Patents by Inventor Siao Ping Tsai

Siao Ping Tsai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-Notch2 Antibodies and Conjugates and Methods of Use
    Publication number: 20230322958
    Abstract: The invention provides anti-Notch2 antibodies and conjugates and methods of using the same.
    Type: Application
    Filed: January 18, 2023
    Publication date: October 12, 2023
    Applicant: Genentech, Inc.
    Inventors: Cornelia Helen Rinderknecht Eller, Adel Mahmoud ElSohly, Kirthana Ganeshan, Daniel George Lafkas, Jian Mehr-Dean Payandeh, Yan Wu, Kathryn Duffy Bewley, Cecilia Pui Chi Chiu, Hoangdung Dang Ho, Siao-Ping Tsai
  • Anti-Notch2 Antibodies and Methods of Use
    Publication number: 20230303682
    Abstract: The invention provides anti-Notch2 antibodies and methods of using the same.
    Type: Application
    Filed: July 16, 2021
    Publication date: September 28, 2023
    Applicant: Genentech, Inc.
    Inventors: Cecilia Pui Chi Chiu, Yan Wu, Adel Mahmoud ElSohly, Daniel George Lafkas, Jian Mehr-Dean Payandeh, Hoangdung Dang Ho, Siao-Ping Tsai
  • Methods and compositions for detection and quantitation of nucleic acid analytes
    Publication number: 20040009506
    Abstract: The present invention provides novel solution phase hybridization-based methods for detecting and quantitating nucleic acid analytes. Methods comprising use of novel capture polymers and/or signaling systems are provided. Use of these novel capture polymers and/or signaling systems provides significant improvements in signal to noise ratio, specificity, sensitivity and ease of development and use as compared to existing solution phase nucleic acid detection and quantitation methods. The invention further provides compositions, kits and articles of manufacture for practicing methods of the present invention.
    Type: Application
    Filed: March 28, 2003
    Publication date: January 15, 2004
    Applicant: GENENTECH, INC.
    Inventors: Jean-Philippe F. Stephan, Siao Ping Tsai, Wai Lee Tan Wong, Todd Billeci
  • SAL-S1 receptor protein tyrosine kinase agonist antibodies
    Patent number: 6673343
    Abstract: Agonist antibodies are disclosed which bind to the extracellular domain of receptor protein tyrosine kinases pTKs, and thereby cause dimerization and activation of the intracellular tyrosine kinase domain thereof. The antibodies are useful for activating their respective receptor and thereby enabling the role of the tyrosine kinase receptor in cell growth and/or differentiation to be studied. Chimeric proteins comprising the extracellular domain of the receptor pTKs and an immunoglobulin constant domain sequence are also disclosed.
    Type: Grant
    Filed: October 17, 2001
    Date of Patent: January 6, 2004
    Assignee: Genentech, Inc.
    Inventors: Brian D. Bennett, David V. Goeddel, James M. Lee, William Matthews, Siao Ping Tsai, William I. Wood
  • Protein tyrosine kinase agonist antibodies
    Publication number: 20020146420
    Abstract: Agonist antibodies are disclosed which bind to the extracellular domain of receptor protein tyrosine kinases pTKs, and thereby cause dimerization and activation of the intracellular tyrosine kinase domain thereof. The antibodies are useful for activating their respective receptor and thereby enabling the role of the tyrosine kinase receptor in cell growth and/or differentiation to be studied. Chimeric proteins comprising the extracellular domain of the receptor pTKs and an immunoglobulin constant domain sequence are also disclosed.
    Type: Application
    Filed: October 17, 2001
    Publication date: October 10, 2002
    Applicant: Genentech, Inc.
    Inventors: Brian D. Bennett, David V. Goeddel, James M. Lee, William Matthews, Siao Ping Tsai, William I. Wood
  • Protein tyrosine kinase agonist antibodies
    Patent number: 6331302
    Abstract: Agonist antibodies are disclosed which bind to the extracellular domain of receptor protein tyrosine kinases pTKs, and thereby cause dimerization and activation of the intracellular tyrosine kinase domain thereof. The antibodies are useful for activating their respective receptor and thereby enabling the role of the tyrosine kinase receptor in cell growth and/or differentiation to be studied. Chimeric proteins comprising the extracellular domain of the receptor pTKs and an immunoglobulin constant domain sequence are also disclosed.
    Type: Grant
    Filed: May 23, 1996
    Date of Patent: December 18, 2001
    Assignee: Genentech, Inc.
    Inventors: Brian D. Bennett, David Goeddel, James M. Lee, William Matthews, Siao Ping Tsai, William I. Wood