Patents by Inventor Siew Chien NG

Siew Chien NG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240127904
    Abstract: The present invention relates to methods for assessing one's risk for suffering from severe COVID or long COVID symptoms. Also provided are methods for reducing the risk of developing severe COVID and/or long COVID symptoms.
    Type: Application
    Filed: June 22, 2023
    Publication date: April 18, 2024
    Inventors: Siew Chien NG, Ka Leung Francis CHAN, Qin LIU
  • Publication number: 20230321166
    Abstract: The present invention resides in the discovery that altered abundance of fungal species in the gut and feces of both fecal microbiota transplantation (FMT) donors and recipients may influence the outcome of FMT treatment. Thus, novel methods are provided for identifying subjects as suitable donor or recipients for FMT, for assessing the likelihood of FMT treatment success, and for enhancing FMT treatment efficacy. Also provided are kits and compositions for FMT with enhanced efficacy.
    Type: Application
    Filed: December 28, 2022
    Publication date: October 12, 2023
    Inventors: Siew Chien NG, Tao ZUO, Ka Leung Francis CHAN
  • Publication number: 20230241128
    Abstract: Methods are provided for treating metabolic diseases by way of modulating recipients' gastrointestinal tract microorganism profile such as by fecal microbiota transplantation (FMT) treatment. Also provided are methods for assessing a patient's risk of developing obesity and/or related metabolic diseases. Further provided are kits and compositions for use in these methods.
    Type: Application
    Filed: May 4, 2021
    Publication date: August 3, 2023
    Inventors: Siew Chien NG, Ka Leung Francis Chan, Tao Zuo
  • Publication number: 20230226123
    Abstract: Provided are methods for treating symptoms of autism spectrum disorder (ASD) in a human child. Methods for determining risk for A SD in human children, methods for assessing developmental age of children and for treating children in need thereof, kits and compositions for use in these methods are also provided.
    Type: Application
    Filed: June 15, 2021
    Publication date: July 20, 2023
    Inventors: Siew Chien NG, Ka Leung Francis CHAN, Zhilu XU, Yating WAN
  • Publication number: 20230227789
    Abstract: Methods and compositions for treating and/or preventing a bacterial infection in a subject are provided, in which the subject is administered a fecal sample obtained from a donor subject via fecal microbiota transplantation (FMT). The fecal sample contains bacteriophages that target the bacteria causing the infection. In some embodiments, the fecal sample containing the bacteriophages can be obtained from a donor subject who previously had the same infection but is now cured.
    Type: Application
    Filed: December 11, 2020
    Publication date: July 20, 2023
    Inventors: Siew Chien NG, Ka Leung Francis CHAN, Qin LIU
  • Publication number: 20230165912
    Abstract: A probiotic composition comprising Bifidobacterium bifidum and Bifidobacterium longum, and may further comprising Bifidobacterium adolescentis and Lactobacillus rhamnosus is provided. A prebiotic composition comprising xylooligosaccharide, galactooligosaccharide, and corn dietary fiber, and a dietary composition comprising the probiotic composition and the prebiotic composition are provided. Use of the foregoing compositions in the preparation of a dietary product or a drug for assisting in preventing and/or treating a pathogen infection of an individual, enhancing the therapeutic effect of a pathogen infection of an individual, improving the immunity of an individual, or balancing the gut microecology of an individual is provided. The foregoing compositions can be used in patients suffering from COVID-19.
    Type: Application
    Filed: April 28, 2021
    Publication date: June 1, 2023
    Inventors: Siew Chien NG, Ka Leung Francis CHAN, Zhilu XU, Wingyan TANG, Qiaoyi LIANG
  • Publication number: 20230165914
    Abstract: Methods are provided for treating COVID-19 patients to facilitate their recovery from the disease as well as for prognosis of severity of COVID-19 among patients who have been infected by SARS-CoV-2. Also provided are kits and compositions for use in these methods.
    Type: Application
    Filed: April 28, 2021
    Publication date: June 1, 2023
    Inventors: Siew Chien NG, Ka Leung Francis CHAN, Tao ZUO, Yun Kit YEOH
  • Publication number: 20230127830
    Abstract: The present invention provides for compositions and methods for treating long COVID symptoms or reducing the risk of developing such symptoms.
    Type: Application
    Filed: October 25, 2022
    Publication date: April 27, 2023
    Inventors: Siew Chien NG, Ka Leung Francis CHAN, Qin LIU
  • Publication number: 20230110611
    Abstract: Certain microorganism species in a composition for use in fecal microbiota transplantation (FMT), including fecal material obtained from an FMT donor, can affect the outcome of FMT treatment such as regulating the bodyweight and cholesterol level in FMT recipients. Thus, methods are provided for identifying subjects as suitable donor to optimize FMT outcome and for pretreating donors and/or recipients for optimized FMT outcome. Also provided are kits and compositions for improving FMT outcome, including for bodyweight and/or cholesterol reduction.
    Type: Application
    Filed: March 29, 2021
    Publication date: April 13, 2023
    Inventors: Siew Chien NG, Tao ZUO, Ka Leung Francis CHAN
  • Patent number: 11331354
    Abstract: The present invention resides in the discovery that abundance and diversity of viral species in the fecal matter from a donor used in fecal microbiota transplantation (FMT) treatment can influence the outcome of the FMT treatment. Thus, novel methods are provided for identifying subjects as suitable donors for FMT, for assessing the likelihood of FMT treatment success, and for enhancing FMT treatment efficacy. Also provided are kits and compositions for FMT with enhanced efficacy.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: May 17, 2022
    Assignee: The Chinese University of Hong Kong
    Inventors: Siew Chien Ng, Tao Zuo
  • Publication number: 20210038663
    Abstract: Methods are provided for identifying subjects as suitable donor or recipients for FMT, for assessing the likelihood of FMT treatment success, and for enhancing FMT treatment efficacy. Also provided are kits and compositions for FMT with enhanced efficacy.
    Type: Application
    Filed: February 1, 2019
    Publication date: February 11, 2021
    Inventors: Siew Chien NG, Tao ZUO, Ka Leung Francis CHAN
  • Publication number: 20190321421
    Abstract: The present invention resides in the discovery that abundance and diversity of viral species in the fecal matter from a donor used in fecal microbiota transplantation (FMT) treatment can influence the outcome of the FMT treatment. Thus, novel methods are provided for identifying subjects as suitable donors for FMT, for assessing the likelihood of FMT treatment success, and for enhancing FMT treatment efficacy. Also provided are kits and compositions for FMT with enhanced efficacy.
    Type: Application
    Filed: March 5, 2019
    Publication date: October 24, 2019
    Inventors: Siew Chien NG, Tao Zuo