Abstract: The present invention pertains to compositions and methods for treating inflammation in a subject in need thereof using hydroxynorketamine (HNK), a salt thereof, a stereoisomer thereof, or a combination thereof.

Abstract: Described embodiments include apparatus that includes a network interface (28) and a processor (30). The processor is configured to receive, via the network interface, speech of a subject (22) who suffers from a pulmonary condition related to accumulation of excess fluid, to identify, by analyzing the speech, one or more speech-related parameters of the speech, to assess, in response to the speech-related parameters, a status of the pulmonary condition, and to generate, in response thereto, an output indicative of the status of the pulmonary condition. Other embodiments are also described.

Abstract: Described embodiments include apparatus that includes a network interface (28) and a processor (30). The processor is configured to receive, via the network interface, speech of a subject (22) who suffers from a pulmonary condition related to accumulation of excess fluid, to identify, by analyzing the speech, one or more speech-related parameters of the speech, to assess, in response to the speech-related parameters, a status of the pulmonary condition, and to generate, in response thereto, an output indicative of the status of the pulmonary condition. Other embodiments are also described.

Abstract: Endoscopes, multicore endoscope fibers and configuration and operation methods are provided. The fibers may have hundreds or thousands of cores and possibly incorporate working channel(s) and additional fibers. The fiber may be used at different optical configurations to capture images of tissue and objects at the distal tip and to enhance a wide range of optical characteristics of the images such as resolution, field of view, depth of field, wavelength ranges etc. Near-field imaging as well as far-field imaging may be implemented in the endoscopes and the respective optical features may be utilized to optimize imaging. Optical elements may be used at the distal fiber tip, or the distal fiber tip may be lens-less. Diagnostics and optical treatment feedback loops may be implemented and illumination may be adapted to yield full color images, depth estimation, enhanced field of views and/or depths of field, and additional diagnostic data.

Abstract: Bone bypass shunts and methods using thereof. Method for affecting a pathophysiological condition in a body of a live subject includes exemplary steps/procedures of: connecting an inlet port of a bone bypass shunt to a first bone portion adjacent a first bone marrow location such that inlet port lumen of inlet port facilitates fluid communication with blood accumulated or flowing at first blood marrow location; connecting outlet port of the bone bypass shunt to second bone portion adjacent second bone marrow location, such that outlet port lumen of outlet port facilitates fluid communication with bone marrow; a formed cavity, or/and bone marrow vasculature, located at second bone marrow location; via inlet port lumen, removing a chosen volume of blood from first bone marrow location; and via outlet port lumen, delivering chosen volume of blood to the second bone marrow location.

Abstract: Endoscopes, multicore endoscope fibers and configuration and operation methods are provided. The fibers may have hundreds or thousands of cores and possibly incorporate working channel(s) and additional fibers. The fiber may be used at different optical configurations to capture images of tissue and objects at the distal tip and to enhance a wide range of optical characteristics of the images such as resolution, field of view, depth of field, wavelength ranges etc. Near-field imaging as well as far-field imaging may be implemented in the endoscopes and the respective optical features may be utilized to optimize imaging. Optical elements may be used at the distal fiber tip, or the distal fiber tip may be lens-less. Diagnostics and optical treatment feedback loops may be implemented and illumination may be adapted to yield full color images, depth estimation, enhanced field of views and/or depths of field, and additional diagnostic data.

Abstract: A computerized method and system for measuring a user's lung capacity and stamina, to detect Chronic Heart Failure, COPD or Asthma, comprising: providing a client application on a user's mobile communication device, said client application comprising executable computer code for: instructing the user to fill his lungs with air and utter vocal sounds within a certain range of loudness (decibels) while exhaling; receiving and registering by the mobile communication device said user's vocal sounds; stopping the registering of vocal sounds; measuring the length of the vocal sounds receiving time within said range of loudness, said time proportionate the user's lung volumes; and displaying the length of sound received time results on the mobile communication device screen.