Patents by Inventor Sigurd Leyck

Sigurd Leyck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5141955
    Abstract: Anti-inflammatory benzylselanobenzamides made from anilines and benzylamines have the formula I ##STR1## are disclosed wherein R is hydrogen, methyl or ethyl;R.sup.1 and R.sup.2 are the same or different and, taken separately, are hydrogen, fluorine, chlorine, bromine, C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, hydroxy, cyano, amino, dimethylamino or nitro; andR.sup.3 and R.sup.4 are the same or different and, taken separately, are hydrogen, fluorine, chlorine, bromine, C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, hydroxy, cyano, or nitro and, taken together, represent methylenedioxy; andn is 0.1 or 2.
    Type: Grant
    Filed: November 8, 1990
    Date of Patent: August 25, 1992
    Assignee: A. Nattermann & Cie. GmbH
    Inventors: Michel Evers, Hartmut Fischer, Jurgen Biedermann, Rolf Terlinden, Sigurd Leyck
  • Patent number: 5114954
    Abstract: Benzylselenobenzamides of formula I ##STR1## with inflammation-inhibiting characteristics and used in pharmaceutical preparations.
    Type: Grant
    Filed: November 8, 1990
    Date of Patent: May 19, 1992
    Assignee: A. Nattermann & Cie. GmbH
    Inventors: Jurgen Biedermann, Michel Evers, Rolf Terlinden, Sigurd Leyck, Erich Graf
  • Patent number: 4910313
    Abstract: The present invention is related to new diselenobis benzoic acid amides of primary heterocyclic amines of the general formula I ##STR1## process for producing the same and process for treating certain diseases in human beings by administration of the same to the humans suffering from such diseases.
    Type: Grant
    Filed: August 6, 1987
    Date of Patent: March 20, 1990
    Assignee: Nattermann & CIE GmbH
    Inventors: Andre Welter, Axel Roemer, Sigurd Leyck, Michael J. Parnham
  • Patent number: 4730053
    Abstract: The present invention is related to new S-(Carbamoyl-phenylselenyl) derivatives of mercaptanes of the general formula (I) ##STR1## and to a process for the treatment of diseases caused by cell injury due to the increased formation of active oxygen metabolites.
    Type: Grant
    Filed: November 25, 1985
    Date of Patent: March 8, 1988
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Norbert Dereu, Albrecht Wendel, Helmut Sies, Sigurd Leyck, Axel Romer, Erich Graf
  • Patent number: 4711961
    Abstract: The invention relates to new benzisoselenazolethiones of the general formula I ##STR1## and to processes for the treatment of various diseases by administering them to such beings.
    Type: Grant
    Filed: February 26, 1985
    Date of Patent: December 8, 1987
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Andre Welter, Sigurd Leyck, Eugen Etschenberg
  • Patent number: 4705802
    Abstract: The invention relates to new .omega.-aryl-alkylthienyl compounds having the Formula I ##STR1## i.e. omega-aryl-alkyl thienyl alkanoic acids and, respectively, omega-aryl-alkyl thienyl alkenoic acids, the alkali metal salts of such acids and certain esters thereof. The invention further relates to processes for the treatment of chronically inflammatory processes in humans.
    Type: Grant
    Filed: February 26, 1985
    Date of Patent: November 10, 1987
    Assignee: A. Nattermann & CIE GmbH
    Inventors: Hans-Heiner Lautenschlager, Michael J. Parnham, Sigurd Leyck, Johannes Winkelmann, Axel Brekle
  • Patent number: 4687766
    Abstract: Pharmaceutical preparation containing phospholipids for the therapeutic treatment of rheumatic diseases which contain in addition to the antiphlogistically acting oxicam derivatives of the general formula ##STR1## special 1,2-diacyl-glycero-3-phosphocholines wherein 75-86% by weight of the acyl radicals are unsaturated fatty acid radicals, and the preparation thereof.
    Type: Grant
    Filed: December 21, 1984
    Date of Patent: August 18, 1987
    Assignee: A. Natterman & Cie, GmbH
    Inventors: Armin Wendel, Sigurd Leyck, Helmut Wetzig, Jorg Hager, Manfred Durr, Miklos Ghyczy
  • Patent number: 4684632
    Abstract: Pharmaceutical formulations for the treatment of gastrointestinal disorders, which contain as the active component an effective gastrointestinal disorder alleviating amount of a 1,2-diacylglycero-3-phosphocholine in which 75-86% by weight of the acyl radicals are unsaturated fatty acid radicals having a chain length of 16, 18 or 20 carbon atoms. The mixtures of fatty acid radicals in the acyl groups in the 1- and 2-positions preferably have different compositions. The formulations can also contain other active compounds, in particular those which display injurious gastrointestinal side effects.
    Type: Grant
    Filed: December 21, 1984
    Date of Patent: August 4, 1987
    Assignee: A. Nattermann & CIE. GmbH
    Inventors: Volker Schulz, Sigurd Leyck, Manfred Durr, Miklos Ghyczy, Armin Wendel, Jorg Hager
  • Patent number: 4667033
    Abstract: The invention refers to substituted 6-(thien-2-yl)-3(2H)-pyridazinones of Formula I ##STR1##
    Type: Grant
    Filed: June 8, 1984
    Date of Patent: May 19, 1987
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Gerd Hilboll, Sigurd Leyck, Gerrit Prop
  • Patent number: 4618605
    Abstract: Disclosed is a process for the production of .beta.-elemonic acid from an alcoholic solution of gum elemi by recovering a crude mixture of elemi acids containing .beta.-elemonic acid, .DELTA..sup.7 .alpha.-elemonic acid and .DELTA..sup.8 .alpha.-elemolic acid by the use of a basic ion exchanger, isomerizing the .DELTA..sup.7 .alpha.-elemolic acid to .DELTA..sup.8 .alpha.-elemolic acid in a chlorinated hydrocarbon by use of a mineral acid, oxidizing the .DELTA..sup.8 .alpha.-elemolic acid to yield additional .beta.-elemonic acid and separating and purifying the total resulting .beta.-elemonic acid from the acid mixture. Also disclosed are pharmaceutical preparations for the treatment of inflammatory conditions containing .beta.-elemonic acid as the active ingredient.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: October 21, 1986
    Inventors: Gunter Stapel, Karl-Heinz Gober, Sigurd Leyck, Helmut Wetzig, Christian Birkner, Kurt Kesselring, Bruno Christ, Klaus Steiner, Friedhelm Schroder
  • Patent number: 4618669
    Abstract: The present invention relates to new S-(carbamoylphenylselenyl) derivatives of glutathione and of .alpha.
    Type: Grant
    Filed: June 14, 1985
    Date of Patent: October 21, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Norbert Dereu, Andre Welter, Albrecht Wendel, Sigurd Leyck, Michael Parnham, Erich Graf, Helmut Sies, Hans Betzing, Hartmut Fischer
  • Patent number: 4610979
    Abstract: The invention relates to new O-acyl-alkanediol-phospholipids of the general formula I ##STR1## processes for their preparation and process for the treatment of certain diseases in humans.
    Type: Grant
    Filed: February 27, 1984
    Date of Patent: September 9, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Erich Graf, Sigurd Leyck
  • Patent number: 4600722
    Abstract: The invention relates to new 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazolines of the Formula I ##STR1## and acid addition salts thereof and a process for the treatment of inflammatory and allergic processes in humans.
    Type: Grant
    Filed: February 26, 1985
    Date of Patent: July 15, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Joachim Uhlendorf, Harald O. Borbe, Sigurd Leyck, Michael J. Parnham, Helmut Wetzig
  • Patent number: 4550168
    Abstract: The invention relates to new benzisoselenazolones of the general formula I ##STR1## and a process for the treatment of humans suffering from inflammatory diseases of the rheumatic type.
    Type: Grant
    Filed: July 12, 1983
    Date of Patent: October 29, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Andre Welter, Sigurd Leyck, Eugen Etschenberg
  • Patent number: 4464379
    Abstract: The present invention is related to new indol acetic acid derivatives having the general formula ##STR1## the salts thereof, processes for producing the same and pharmaceutical preparations comprising the same as well as their use as drugs having antithrombotic, antiarteriosclerotic and antiphlogistic activity.
    Type: Grant
    Filed: June 1, 1981
    Date of Patent: August 7, 1984
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans Betzing, Sigurd Leyck
  • Patent number: 4454068
    Abstract: The invention relates to new benzisoselenazolones of the general formula I ##STR1## and to the use thereof in the treatment of inflammatory diseases in humans.
    Type: Grant
    Filed: July 12, 1983
    Date of Patent: June 12, 1984
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Andre Welter, Sigurd Leyck, Eugen Etschenberg
  • Patent number: 4397858
    Abstract: The invention relates to the new use of certain benzisothiazoles corresponding to the following general formula: ##STR1## wherein R.sub.1 represents chlorine, fluorine or bromine, and R.sub.2 represents hydrogen, chlorine, fluorine or bromine, in the treatment of phlogistic and/or arteriosclerotic processes.
    Type: Grant
    Filed: October 22, 1981
    Date of Patent: August 9, 1983
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Andre Welter, Hans-Heiner Lautenschlager, Eugen Etschenberg, Sigurd Leyck