Patents by Inventor Silin Pang

Silin Pang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical compound of isocitrate dehydrogenase inhibitor, and application thereof
    Patent number: 10961222
    Abstract: Provided are a chemical compound of an isocitrate dehydrogenase inhibitor, and an application thereof, belonging to the field of medicinal chemistry; specifically provided is the chemical compound represented by formula I, or its isomer, pharmaceutically acceptable salt, crystal, solvate, or prodrug, as well as their preparation methods and pharmaceutical compositions containing said chemical compound, and an application of said chemical compound or composition. The chemical compound has very good ability to inhibit mutant IDH2 enzyme activity and to inhibit mutant IDH2 neoplastic cells, and may be used for preventing and/or treating a tumor characterized by the presence of mutant IDH2.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: March 30, 2021
    Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong Wang, Liwen Zhao, Xiaorong Liu, Yan Zhang, Dandan Huang, Chunhuan Jiang, Xinsheng Shi, Hongfeng Gu, Silin Pang, Wei Hai, Bingyang Ge
  • CHEMICAL COMPOUND OF ISOCITRATE DEHYDROGENASE INHIBITOR, AND APPLICATION THEREOF
    Publication number: 20190161473
    Abstract: Provided are a chemical compound of an isocitrate dehydrogenase inhibitor, and an application thereof, belonging to the field of medicinal chemistry; specifically provided is the chemical compound represented by formula I, or its isomer, pharmaceutically acceptable salt, crystal, solvate, or prodrug, as well as their preparation methods and pharmaceutical compositions containing said chemical compound, and an application of said chemical compound or composition. The chemical compound has very good ability to inhibit mutant IDH2 enzyme activity and to inhibit mutant IDH2 neoplastic cells, and may be used for preventing and/or treating a tumor characterized by the presence of mutant IDH2.
    Type: Application
    Filed: July 20, 2017
    Publication date: May 30, 2019
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong WANG, Liwen ZHAO, Xiaorong LIU, Yan ZHANG, Dandan HUANG, Chunhuan JIANG, Xinsheng SHI, Hongfeng GU, Silin PANG, Wei HAI, Bingyang GE
  • APPLICATION OF FLUOXETINE TO TREATMENT OF DEPIGMENTATION DISEASES
    Publication number: 20160256419
    Abstract: The present disclosure provides methods and pharmaceutical compositions for treating depigmentation diseases such as vitiligo or leukoctricia. The pharmaceutical composition contains a therapeutically effective amount of fluoxetine.
    Type: Application
    Filed: May 17, 2016
    Publication date: September 8, 2016
    Inventors: Jing SHANG, Sha LIAO, Yu JIN, Xiaoli TIAN, Guorui ZHAO, Jia ZHOU, Qian WANG, Silin PANG
  • APPLICATION OF FLUOXETINE TO TREATMENT OF DEPIGMENTATION DISEASES
    Publication number: 20150065580
    Abstract: The present invention relates to the field of medicine and particularly relates to the application of fluoxetine to the treatment of depigmentation diseases. Pharmacodynamic tests have demonstrated that fluoxetine has the effects of treating depigmentation diseases especially leukotrichia and vitiligo.
    Type: Application
    Filed: December 5, 2012
    Publication date: March 5, 2015
    Applicant: SHANDONG RUNZE PHARMACEUTICALS CO., LTD.
    Inventors: Jing Shang, Sha Liao, Yu Jin, Xiaoli Tian, Guorui Zhao, Jia Zhou, Qian Wang, Silin Pang