Patents by Inventor Silvana Konermann

Silvana Konermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL CRISPR ENZYMES AND SYSTEMS
    Publication number: 20210348157
    Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
    Type: Application
    Filed: April 30, 2021
    Publication date: November 11, 2021
    Inventors: Eugene Koonin, Feng Zhang, Yuri I. Wolf, Sergey Shmakov, Konstantin Severinov, Ekaterina Semenova, Leonid Minakhin, Kira S. Makarova, Silvana Konermann, Julia Joung, Jonathan S. Gootenberg, Omar O. Abudayyeh
  • NOVEL CRISPR ENZYMES AND SYSTEMS
    Publication number: 20210348156
    Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
    Type: Application
    Filed: April 30, 2021
    Publication date: November 11, 2021
    Inventors: Eugene Koonin, Feng Zhang, Yuri I. Wolf, Sergey Shmakov, Konstantin Severinov, Ekaterina Semenova, Leonid Minakhin, Kira S. Makarova, Silvana Konermann, Julia Joung, Jonathan S. Gootenberg, Omar O. Abudayyeh
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20210344627
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 21, 2021
    Publication date: November 4, 2021
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20210344630
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 21, 2021
    Publication date: November 4, 2021
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20210344626
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 21, 2021
    Publication date: November 4, 2021
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20210344629
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 21, 2021
    Publication date: November 4, 2021
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20210344628
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 21, 2021
    Publication date: November 4, 2021
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20210344631
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 21, 2021
    Publication date: November 4, 2021
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • CRISPR enzymes and systems
    Patent number: 11060115
    Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: July 13, 2021
    Assignees: The Broad Institute, Inc., Massachusetts Institute of Technology, President and Fellows of Harvard College, Rutgers, the State University of New Jersey, Skolkovo Institute of Science and Technology, The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Konstantin Severinov, Feng Zhang, Yuri I. Wolf, Sergey Shmakov, Ekaterina Semenova, Leonid Minakhin, Kira S. Makarova, Eugene Koonin, Silvana Konermann, Julia Joung, Jonathan S. Gootenberg, Omar O. Abudayyeh, Eric S. Lander
  • RNA targeting methods and compositions
    Patent number: 11032224
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: June 8, 2021
    Assignee: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA targeting methods and compositions
    Patent number: 11032225
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: June 8, 2021
    Assignee: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA targeting methods and compositions
    Patent number: 11025574
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: June 1, 2021
    Assignee: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • Functional screening with optimized functional CRISPR-Cas systems
    Patent number: 11001829
    Abstract: The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the Cas protein of the CRISPR-Cas system, use of this information in generating modified components of the CRISPR complex, vectors and vector systems which encode one or more components or modified components of a CRISPR complex, as well as methods for the design and use of such vectors and components. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system. In particular the present invention comprehends optimized functional CRISPR-Cas enzyme systems.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: May 11, 2021
    Assignees: The Broad Institute, Inc., Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Feng Zhang, Silvana Konermann, Mark D. Brigham, Alexandra Trevino
  • RNA targeting methods and compositions
    Patent number: 11005799
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: May 11, 2021
    Assignee: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA targeting methods and compositions
    Patent number: 10931613
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: February 23, 2021
    Assignee: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20200351231
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 3, 2020
    Publication date: November 5, 2020
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20200351232
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 3, 2020
    Publication date: November 5, 2020
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20200322297
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: June 3, 2020
    Publication date: October 8, 2020
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20200252359
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: March 17, 2020
    Publication date: August 6, 2020
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann
  • RNA TARGETING METHODS AND COMPOSITIONS
    Publication number: 20200244609
    Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.
    Type: Application
    Filed: January 30, 2020
    Publication date: July 30, 2020
    Applicant: Salk Institute for Biological Studies
    Inventors: Patrick D. Hsu, Silvana Konermann